Design and development of supported catalysts due to computational physics and experiments for save and reuse of rare elements for catalyst

• Project/Area Number: 23246013
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Thin film/Surface and interfacial physical properties
• Research Institution: Tottori University
• Principal Investigator: ISHII Akira 鳥取大学, 工学(系)研究科(研究院), 教授 (70183001)
• Co-Investigator(Kenkyū-buntansha): OKUMURA Kazu 工学院大学, 工学部応用化学科, 教授 (30294341) ; ARISAWA Mitsuhiro 大阪大学, 薬学研究科(研究院), 准教授 (40312962)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥49,790,000 (Direct Cost: ¥38,300,000、Indirect Cost: ¥11,490,000); Fiscal Year 2014: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000); Fiscal Year 2013: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000); Fiscal Year 2012: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000); Fiscal Year 2011: ¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
• Keywords: 環境対応 / 計算物理 / 合成化学 / 触媒・化学プロセス / 薬学

Outline of Final Research Achievements

In this project, we investigate using compupuational physics and experiments for Pd catalyst on zeolite and on sulfer-covered gold plate.
Pd K-edge extended XAFS analysis for USY zeolite reveals the presence of molecular-like PdO and a mixture of Pd/PdO before and after the reaction, respectively.Pd stabilized by Al sites is present at the II sites of the Y-type zeolite, as estimated using first-principles calculations. The structure of the Pd catalyst, named sulfur-modified gold-supported palladium (SAPd), has been determined to be composed of multi-layered Pd nanoparticles. NEXAFS analysis revealed that the organic matter containing sulfate and xylene as a major ingredient is distributed between Pd nanoparticles.The computational physics approach find the suitable sites on zeolite inner space for Pd catalyst. Moreover,we find the role of SO4 in the case of SAPd that SO4 on gold surface leave gold and adsorb on Pd nano particles. The same mechanism will occor for Ni, also.

Research Products

• [Journal Article] Suzuki Coupling Reactions Catalyzed by PdO Dispersed on Dealuminated Y Zeolite in Air under Ambient Conditions (2015)
  • Author(s): Kazu Okumura, Takumi Mushiake, Yu Matsui, Akira Ishii
  • Journal Title: ChemPhycChem Volume: 未定 Issue: 8 Pages: 1719-1726
  • DOI: 10.1002/cphc.201500118
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Relationship between activation energy and pre-exponential factor normalized by the number of Bronsted acid sites in cracking of short chain alkanes on zeolites (2015)
  • Author(s): Naonobu Katada, Satoko Sota, Nami Morishita, Kazu Okumura, Miki Niwa
  • Journal Title: Catal. Sci. Technol. Volume: 5 Issue: 3 Pages: 1864-1869
  • DOI: 10.1039/c4cy01483a
  • Peer Reviewed
• [Journal Article] Post-synthesized zirconium-containing Beta zeolite in Meerwein-Ponndorf-Verley reduction: Pros and cons (2015)
  • Author(s): Jie Wang,Kazu Okumura, Stephan Jaenicke, Gaik-Khuan Chuah
  • Journal Title: Appl. Catal. A Volume: 493 Pages: 112-120
  • DOI: 10.1016/j.apcata.2015.01.001
  • Peer Reviewed
• [Journal Article] Hydrodeoxygenation of Vicinal OH Groups over Heterogeneous Rhenium Catalyst Promoted by Palladium and Ceria Support (2015)
  • Author(s): Nobuhiko Ota, Masazumi Tamura, Yoshinao Nakagawa, Kazu Okumura, Keiichi Tomishige
  • Journal Title: Angew. Chem. Volume: 54 Issue: 6 Pages: 1897-1900
  • DOI: 10.1002/anie.201410352
  • Peer Reviewed
• [Journal Article] Selective hydrogenation of lactic acid to 1,2-propanediol over highly active Ru-MoOx catalysts (2015)
  • Author(s): Y. Takeda, T. Shoji, H. Watanabe, M. Tamura, Y. Nakagawa, K. Okumura and K. Tomishige
  • Journal Title: ChemSusChem Volume: 8 Issue: 7 Pages: 1170-1178
  • DOI: 10.1002/cssc.201403011
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Formation of self-assembled multi-layer stable palladium nanoparticles for ligand-free coupling reactions (2015)
  • Author(s): Mitsuhiro Arisawa, Mohammad Al-Amin, Tetsuo Honma, Yusuke Tamenori, Satoshi Arai, Naoyuki Hoshiya, Takatoshi Sato, Mami Yokoyama, Akira Ishii, Masaki Takeguchi, Tsuyoshi Miyazaki, Masashi Takeuchi, Tomohiro Maruko, Satoshi Shuto
  • Journal Title: RSC Adv. Volume: 5 Issue: 1 Pages: 676-683
  • DOI: 10.1039/c4ra11215f
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Nickel-Catalyzed Suzuki-Miyaura Coupling of a Tertiary Iodocyclopropane with Wide Boronic Acid Substrate Scope: Coupling Reaction Outcome Depends on Radical Species Stability (2015)
  • Author(s): Keisuke Yotsuji, Naoyuki Hoshiya, Takaaki Kobayashi, Hayato Fukuda, Hiroshi Abe, Mitsuhiro Arisawa and Satoshi Shuto
  • Journal Title: Adv. Synth. Catal. Volume: 357 Issue: 5 Pages: 1022-1028
  • DOI: 10.1002/adsc.201401000
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Double Carbonylation of Aryl Iodides with Amines under an Atmospheric Pressure of Carbon Monoxide Using Sulfur- Modified Au-Supported Palladium (2015)
  • Author(s): Nozomi Saito Takahisa Taniguchi, Naoyuki Hoshiya, Satoshi Shuto, Mitsuhiro Arisawa, Yoshihiro Sato
  • Journal Title: Green Chem. Volume: 17 Issue: 4 Pages: 2358-2361
  • DOI: 10.1039/c4gc02469a
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 芳香族エナミドメタセシス反応の開発：生物活性多置換インドール化合物の設計・合成・機能評価 (2015)
  • Author(s): 有澤光弘、西田篤司、周東智
  • Journal Title: 有機合成化学協会誌 Volume: 73 Pages: 254-265
  • NAID: 130005065812
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Safe Removal of the Allyl Protecting Groups of Allyl Esters using a Recyclable, Low-leaching and Ligand-free Palladium Nanoparticle Catalyst (2015)
  • Author(s): Koji Takagi, Hayato Fukuda, Satoshi Shuto, Akira Otaka, Mitsuhiro Arisawa
  • Journal Title: Adv. Synth. Catal. Volume: 357
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Catalytic Cracking of Methyl tert-Butyl Ether to Isobutene over Bronsted and Lewis Acid Siteson Solid-state Molybdenum Sulfide Clusters with an Octahedral Metal Framework (2014)
  • Author(s): Satoshi Kamiguchi, Yasunari Seki, Akiharu Satake, Kazu Okumura, Sayoko Nagashima, Teiji Chihara
  • Journal Title: J. Clust. Sci. Volume: 25 Issue: 3 Pages: 1203-1224
  • DOI: 10.1007/s10876-014-0781-6
  • Peer Reviewed
• [Journal Article] Rational hopping of a peptidic scaffold into non-peptidic scaffolds: structurally novel potent proteasome inhibitors derived from a natural product, belactosin A (2014)
  • Author(s): Shuhei Kawamura, Yuka Unno, Takatsugu Hirokawa, Akira Asai, Mitsuhiro Arisawa and Satoshi Shuto
  • Journal Title: Chem. Commun. Volume: 50 Pages: 2445-2447
  • NAID: 120005525210
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Palladium-Nanoparticle-Catalyzed Direct Ethynylation of Aliphatic Carboxylic Acid Derivatives via C(sp3)-H Bond Functionalization (2014)
  • Author(s): Mohammad Al-Amin, Mitsuhiro Arisawa, Satoshi Shuto, Yusuke Ano, Mamoru Tobisu, Naoto Chatani
  • Journal Title: Adv. Synth. Catal. Volume: 356 Issue: 7 Pages: 1631-1637
  • DOI: 10.1002/adsc.201301180
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Ligandーfree Suzuki-Miyaura Coupling with Sulfur-modified Gold-supported Palladium in the Synthesis of a Conformationally-Restricted Cyclopropane Compound Library with Three-Dimensional Diversity (2014)
  • Author(s): Mitsuhiro ARISAWA
  • Journal Title: ACS Combi. Sci. Volume: 16 Issue: 5 Pages: 215-220
  • DOI: 10.1021/co4001138
  • Peer Reviewed / Open Access
• [Journal Article] Palladium-Nanoparticle-Catalyzed 1,7-Palladium Migration Involving C-H Activation, Followed by Intramolecular Amination: Regioselective Synthesis of N1-Arylbenzotriazoles and an Evaluation of Their Inhibitory Activity Towards Indoleamine 2,3-Dioxygenase (2014)
  • Author(s): Koji Takagi, Mohammad Al-Amin, Naoyuki Hoshiya, Johan Wouters, Hiroshi Sugimoto, Yoshitsugu Shiro, Hayato Fukuda, Satoshi Shuto, Mitsuhiro Arisawa
  • Journal Title: J. Org. Chem. Volume: 79 Issue: 13 Pages: 6366-6371
  • DOI: 10.1021/jo5009838
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Development of a New Class of Proteasome Inhibitors with an Epoxyketone Warhead: Rational Hybridization of Non-peptidic Belactosin Derivatives and Peptide Epoxyketones (2014)
  • Author(s): Shuhei Kawamura, Yuka Unno, Akira Asai, Mitsuhiro Arisawa, Satoshi Shuto
  • Journal Title: Bioorg. Med. Chem. Volume: 22 Issue: 12 Pages: 3091-3095
  • DOI: 10.1016/j.bmc.2014.04.032
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor (2014)
  • Author(s): Takaaki Kobayashi, Akihiro Suemasa, Arisa Igawa, Soichiro Ide, Hayato Fukuda, Hiroshi Abe, Mitsuhiro Arisawa, Masabumi Minami, Satoshi Shuto
  • Journal Title: ACS Med. Chem. Lett. Volume: 5 Issue: 8 Pages: 889-893
  • DOI: 10.1021/ml500134k
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Density functional theory calculation for Pd adsorption on adsorbed SO4 on Graphene. (2014)
  • Author(s): M.Yokoyama, K.Nakada and A.Ishii
  • Journal Title: Comput. Material Sci. Volume: 83 Pages: 418-425
  • DOI: 10.1016/j.commatsci.2013.11.004
  • Peer Reviewed
• [Journal Article] Density functional theory calculations for Pd adsorption on SO4 adsorbed on h-BN. (2014)
  • Author(s): M.Yokoyama, K.Nakada and A.Ishii
  • Journal Title: Comput.Material Sci. Volume: 82 Pages: 231-236
  • DOI: 10.1016/j.commatsci.2013.08.058
  • Peer Reviewed
• [Journal Article] Investigation of the Non-Covalent Binding Mode of Covalent Proteasome Inhibitors around the Transition State by Combined Use of Cyclopropylic Strain-Based Conformational Restriction and Computational Modeling (2013)
  • Author(s): Shuhei KAWAMURA
  • Journal Title: J. Med. Chem. Volume: 56 Issue: 14 Pages: 5829-5842
  • DOI: 10.1021/jm400542h
  • Peer Reviewed / Open Access
• [Journal Article] One-Pot Ring-Closing Metathesis/1, 3-Dipolar Cycloaddition through Assisted Tandem Ruthenium Catalysis: Synthesis of a Dye with Isoindolo[2, 1-a]quinoline Structure (2013)
  • Author(s): Mitsuhiro Arisawa, Yuki Fujii, Hiroshige Kato, Hayato Fukuda, Takashi Matsumoto, Mika Ito, Hiroshi Abe, Yoshihiro Ito, and Satoshi Shuto
  • Journal Title: Angewandte Chemie International Edition Volume: 51 Issue: 3 Pages: 1003-1007
  • DOI: 10.1002/anie.201206765
  • Peer Reviewed
• [Journal Article] Three-Dimensional Structural Diversity-Oriented Peptidomimetics Based on the Cyclopropylic Strain. (2013)
  • Author(s): Akira MIZUNO
  • Journal Title: Org.Lett. Volume: 15 Pages: 1686-1689
  • Peer Reviewed
• [Journal Article] Conformational Restriction Approach to BACE1 InhibitorsII:SAR Study of the Isocytosine Derivatives Fixed with a cis-Cyclopropane Ring. (2013)
  • Author(s): Shuji YONEZAWA
  • Journal Title: Bioorg.Med.Chem.Lett. Volume: 23 Issue: 10 Pages: 2912-2915
  • DOI: 10.1016/j.bmcl.2013.03.056
  • Peer Reviewed
• [Journal Article] Suzuki-Miyaura cross-coupling reactions using a low-leaching and highly recyclable gold-supported palladium material and two types of microwave equipments (2013)
  • Author(s): M. Al-Amin, M. Akimoto, T. Tameno, X. Ohoki, N. Takahashi, N. Hoshiya, S. Shuto, M. Arisawa
  • Journal Title: Green Chemistry Volume: 16 Issue: 5 Pages: 1142-1145
  • DOI: 10.1039/c3gc00063j
  • Peer Reviewed
• [Journal Article] Potent Proteasome Inhibitors Derived from the Unnatural Cis-Cyclopropane Isomer of Belactosin A: Synthesis, Biological Activity, and Mode of Action. (2013)
  • Author(s): Shuhei KAWAMURA
  • Journal Title: J. Med. Chem. Volume: 56 Issue: 9 Pages: 3689-3700
  • DOI: 10.1021/jm4002296
  • Peer Reviewed
• [Journal Article] Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger. (2013)
  • Author(s): Tsuzuki, T., Sakaguchi, N., Kudoh, T., Takano, S., Uehara, M., Murayama, T., Sakurai, T., Hashii, M., Higashida, H., Weber, K., Guse, A.H., Kameda, T., Hirokawa, T., Kumaki, Y., Potter, B.V., Fukuda, H., Arisawa, M., Shuto, S.
  • Journal Title: Angew. Chem. Int. Ed. Engl Volume: 52 Issue: 26 Pages: 6633-6637
  • DOI: 10.1002/anie.201302098
  • Peer Reviewed
• [Journal Article] Design Synthesis, and Validation of Peptidomimetics with Three-dimentional Structure Diversity (2013)
  • Author(s): Akira MIZUMO
  • Journal Title: Peptide Science Volume: 49 Pages: 9-10
  • Peer Reviewed
• [Journal Article] DJ-1 cooperates with PYCR1 in cell protection against oxidative stress (2013)
  • Author(s): Tatsuki YASUDA
  • Journal Title: Biochem. Biophys. Res. Commun. Volume: 436 Pages: 289-294
  • Peer Reviewed
• [Journal Article] Development of Second Generation Gold-Supported Palladium Material with Low-Leaching and Recyolable Characteristics in Aromatic Amination (2013)
  • Author(s): M. Al-Amin, S. Arai, N. Hashiya, T. Honma, Y. Tamenori, T. Sato, M. Yokoyama, A. Ishii, M. Takeuchi, T. Maruko, S. Shuto, M. Arisawa
  • Journal Title: Journal of Organic Chemistry Volume: 78 Issue: 15 Pages: 7575-7581
  • DOI: 10.1021/jo4011415
  • Peer Reviewed
• [Journal Article] Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: Identification of an efficient lead for potent inhibitors of GABA transports (2013)
  • Author(s): Kazuaki NAKADA
  • Journal Title: Bioorg. Med. Chem. Volume: 21 Pages: 4938-4950
  • Peer Reviewed
• [Journal Article] A fluorescence-based method for evaluating inositol 1,4,5-trisphosphate receptor ligands: Determination of subtype selectivity and partial agonist effects (2013)
  • Author(s): Akihiko TANIMURA
  • Journal Title: Journal of Biotechnology Volume: 167 Issue: 3 Pages: 248-254
  • DOI: 10.1016/j.jbiotec.2013.06.012
  • Peer Reviewed
• [Journal Article] Design and synthesis of the stabilized analogs of belactosin A with the unnatural cis-cyclopropane structure (2013)
  • Author(s): Shuhei KAWAMURA
  • Journal Title: Org. Biomol. Chem Volume: 11 Issue: 38 Pages: 6615-6622
  • DOI: 10.1039/c3ob41338a
  • Peer Reviewed
• [Journal Article] Conformational restriction approach toβ-secretase (BACE1) inhibitors III: Effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations (2013)
  • Author(s): Shuji YONEZAWA
  • Journal Title: Bioorg. Med. Chem. Volume: 21 Pages: 6506-6522
  • Peer Reviewed
• [Journal Article] Preparation of nonracemic bromomethylenecyclopropane and its use in Suzuki-Miyaura coupling; synthesis of the arylmethyl-cis-cyclopropane structure core. (2013)
  • Author(s): Makoto TANABE
  • Journal Title: J. Org. Chem. Volume: 78 Issue: 23 Pages: 11714-11720
  • DOI: 10.1021/jo401675z
  • Peer Reviewed
• [Journal Article] Palladium-Catalyzed Arylation of Cyclopropanes via Directing Group-Mediated C(sp3)&H Bond Activation To Construct Quaternary Carbon Centers: Synthesis of cis- and trans-1,1,2-Trisubstituted Chiral Cyclopropanes (2013)
  • Author(s): Naoyuki HOSHIYA
  • Journal Title: Org. Lett. Volume: 15 Issue: 17 Pages: 6203-6205
  • DOI: 10.1021/ja00772a052
  • Peer Reviewed
• [Journal Article] Dependence of cracking activity on the Brønsted acidity of Y zeolite: DFT study and experimental confirmation (2013)
  • Author(s): Miki Niwa, Katsuki Suzuki, Nami Morishita, German Sastre, Kazu Okumura, Naonobu Katada
  • Journal Title: Catalysis Science and Technology Volume: 8 Issue: 8 Pages: 1919-1927
  • DOI: 10.1039/c3cy00195d
  • Peer Reviewed
• [Journal Article] Structure and catalysis of layered Nb-W oxide constructed by the self-assembly of nanofibers (2013)
  • Author(s): Kazu Okumura, Soichiro Ishida, Ryota Takahata, Naonobu Katada
  • Journal Title: Catalysis Today Volume: 204 Pages: 197-203
  • DOI: 10.1016/j.cattod.2012.06.034
• [Journal Article] Fabrication and Catalytic Activity of Thermally Stable Gold Nanoparticles on Ultrastable Y (USY) Zeolites (2013)
  • Author(s): Takashi Sanada, Chika Murakami, Kinga Góra-Marek, Keiko Iida, Naonobu Katada, Kazu Okumura
  • Journal Title: Catalysts Volume: 3 Issue: 3 Pages: 599-613
  • DOI: 10.3390/catal3030599
• [Journal Article] Application of Solid-State Molybdenum Sulfide Clusters with an Octahedral Metal Framework to Catalysis: Ring-Opening of Tetrahydrofuran to Butyraldehyde (2013)
  • Author(s): Satoshi Kamiguchi, Kazu Okumura, Sayoko Nagashima, Teiji Chihara Kazu Okumura, Soichiro Ishida, Naonobu Katada
  • Journal Title: Journal of Cluster Science Volume: 24 Issue: 2 Pages: 559-574
  • DOI: 10.1007/s10876-012-0534-3
  • Peer Reviewed
• [Journal Article] Three-Dimensional Structural Diversity-Oriented Peptidomimetics Based on the Cyclopropylic Strain (2013)
  • Author(s): Akira Mizuno
  • Journal Title: Org. Lett. Volume: 15 Issue: 7 Pages: 1686-1689
  • DOI: 10.1021/ol400469w
  • Peer Reviewed
• [Journal Article] DFT Studies of S-Modified Au-Supported Pd with Hydroxyl Group (2012)
  • Author(s): Mami Yokoyama
  • Journal Title: e-Journal of Surface Science and Nanotechnology Volume: 10 Issue: 0 Pages: 630-632
  • DOI: 10.1380/ejssnt.2012.630
  • NAID: 130004933770
  • ISSN: 1348-0391
  • Peer Reviewed
• [Journal Article] Structure of ReOx Clusters Attached on the Ir Metal Surface in Ir-ReO_x/SiO_2 for the Hydrogenolysis Reaction (2012)
  • Author(s): Y. Amada, H. Watanabe, M. Tamura, Y. Nakagawa, K. Okumura and K. Tomishige
  • Journal Title: J. Phys. Chem. C Volume: 116 Issue: 44 Pages: 23503-23514
  • DOI: 10.1021/jp308527f
  • Peer Reviewed
• [Journal Article] Formation and catalysis of mesoporous Nb-Mo oxide generated by the self-assembly of nanoparticles (2012)
  • Author(s): Kazu Okumura
  • Journal Title: Chem. Lett. Volume: 41 Issue: 9 Pages: 947-949
  • DOI: 10.1246/cl.2012.947
  • NAID: 10031031290
  • Peer Reviewed
• [Journal Article] Comparative study of Rh-MoOx and Rh-ReOx supported on SiO2 for the hydrogenolysis of ethers and polyols (2012)
  • Author(s): Shuichi Koso
  • Journal Title: Appl. Catal. B Volume: 111 Pages: 23-37
  • Peer Reviewed
• [Journal Article] Stable Low-Valence ReO_x Cluster Attached on Rh Metal Particles Formed by Hydrogen Reduction and its Formation Mechanism (2012)
  • Author(s): Shuichi Koso, Hideo Watanabe, Kazu Okumura, Yoshinao Nakagawa, Keiichi Tomishige
  • Journal Title: Journal of Physical Chemistry C Volume: 116 Issue: 4 Pages: 3079-3090
  • DOI: 10.1021/jp2114225
  • Peer Reviewed
• [Journal Article] Formation of nanometer-sized Au particles on USY zeolites under hydrogen atmosphere (2012)
  • Author(s): Kazu Okumura
  • Journal Title: Gold Bulletin Volume: 45 Issue: 2 Pages: 83-90
  • DOI: 10.1007/s13404-012-0051-z
  • Peer Reviewed
• [Journal Article] Spontaneous Dispersion of Gold Nanoparticles Loaded on USY Zeolites as Analyzed by XAFS, XRD, and TEM (2012)
  • Author(s): Takashi Sanada, Kazu Okumura, Chika Murakami, Tetsuya Oyama, Ayano Isoda, Naonobu Katada
  • Journal Title: Chemistry Letters Volume: 41 Issue: 3 Pages: 337-339
  • DOI: 10.1246/cl.2012.337
  • NAID: 10030224846
  • Peer Reviewed
• [Journal Article] リユース可能なスモールリリース型「硫黄修飾金に担持したパラジウム触媒」の開発 (2012)
  • Author(s): 有澤光弘
  • Journal Title: 触媒 Volume: 54 Pages: 197-202
  • NAID: 10030518650
  • Peer Reviewed
• [Journal Article] Design and Synthesis of Indomethacin Analogues That Inhibit P-Glycoprotein and/or Multidrug Resistant Protein without Cox Inhibitory Activity (2012)
  • Author(s): Mitsuhiro Arisawa, Yayoi Kasaya, Tohru Obata, Takuma Sasaki, Tomonori Nakamura, Takuya Araki, Koujirou Yamamoto, Akito Sasaki, Akihito Yamano, Mika Ito, Hiroshi Abe, Yoshihiro Ito, and Satoshi Shuto
  • Journal Title: Journal of Medicinal Chemistry Volume: 55 Issue: 18 Pages: 8152-8163
  • DOI: 10.1021/jm301084z
  • Peer Reviewed
• [Journal Article] Cyclopropane-Based Stereochemical Diversity-Oriented Conformational Restriction Strategy : Histamine Analog swith the4-Amino-2, 3-methano-1-(1H-imidazol-4-yl) butane Structure as Highly PotentHistamine H_3 and/or H4 Receptor Ligands. Org (2012)
  • Author(s): M. Watanabe, T. Kobayashi, T. Hirokawa, A. Yoshida, Y. Ito, S. Yamada, N. Orimoto, Y. Yamasaki, M. Arisawa, S. Shuto
  • Journal Title: Biomol. Chem Volume: 10 Issue: 4 Pages: 736-745
  • DOI: 10.1039/c1ob06496g
  • Peer Reviewed
• [Journal Article] Ligand-Free Buchwald-Hartwig Aromatic Aminations of Aryl Halides Catalyzed by Low-Leaching and Highly Recyclable Sulfur-Modified Gold-Supported Palladium Material (2012)
  • Author(s): Mohammad Al-Amin, Tetsuo Honma, Naoyuki Hoshiya, Takatoshi Sato, Satoshi Shuto, Mitsuhiro Arisawa
  • Journal Title: Adv.Synth.Catal. Volume: 354 Issue: 6 Pages: 1061-1068
  • DOI: 10.1002/adsc.201100761
  • Peer Reviewed
• [Journal Article] Ruthenium-catalyzed cycloisomerization of 1,3-dienes, for example, an N-dienyl-2-vinylaniline derivative, leading to a 3-Exomethylene-2-vinylindole derivative and its application to the synthesis of (±)-cinchonaminone (2012)
  • Author(s): Takao Ogawa
  • Journal Title: Eur. J. Org. Chem. Volume: - Issue: 16 Pages: 3084-3087
  • DOI: 10.1002/ejoc.201200260
  • Peer Reviewed
• [Journal Article] A Conformational Restriction Approach to β-secretase (BACE1) Inhibitors: Effect of a Cyclopropane Ring to Induce an Alternative Binding Mode (2012)
  • Author(s): Shuji Yonezawa
  • Journal Title: J. Med. Chem. Volume: 55 Issue: 20 Pages: 8838-8858
  • DOI: 10.1021/jm3011405
  • Peer Reviewed
• [Journal Article] Comparative study of Rh-MoOx and Rh-ReOx supported on SiO2 for the hydrogenolysis of ethers and polyols (2012)
  • Author(s): Shuichi Koso
  • Journal Title: Applied Catalysis B-Environmental Volume: 111 Pages: 27-37
  • Peer Reviewed
• [Journal Article] Ruthenium-catalyzed cycloisomerization of 1,3-dienes, for example, an N-dienyl-2-vinylaniline derivative. leading to a 3-Exomethylene-2-vinylindole derivative and its application to the synthesis of (±)-cinchonaminone (2012)
  • Author(s): Takao Ogawa
  • Journal Title: Eur.J.Org.Chem. Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Density Functional Theory for Green Chemical Catalyst Supported on S-Terminated GaN(0001) (2011)
  • Author(s): M.Yokoyama
  • Journal Title: AIP Conf.Proc. Volume: VOL.1399 Pages: 205-206
  • DOI: 10.1063/1.3666327
  • Peer Reviewed
• [Journal Article] DFT calculation for Green Chemical Catalyst with hydroxyl group supported on S-Terminated GaN(0001) (2011)
  • Author(s): M.Yokoyama
  • Journal Title: physica status solidi(c) Volume: VOL.8 Issue: 5 Pages: 1594-1596
  • DOI: 10.1002/pssc.201100003
  • Peer Reviewed
• [Journal Article] Evolution of strong acidity and high-alkane-cracking activity in ammonium-treated USY zeolites (2011)
  • Author(s): K.Okumura, T.Tomiyama, N.Morishita, T.Sanada, K.Kamiguchi, N.Katada, M.Niwa
  • Journal Title: Applied Catalysis, A : General Volume: 405 Issue: 1-2 Pages: 8-17
  • DOI: 10.1016/j.apcata.2011.07.007
  • Peer Reviewed
• [Journal Article] Addition of olefins to acetylacetone catalyzed by cooperation of Bronsted acid site of zeolite and gold cluster (2011)
  • Author(s): Ken-ichi Shimizu, Takumi Yamamoto, Yutaka Tai, Kazu Okumura, Atsushi Satsuma
  • Journal Title: Applied Catalysis A : General Volume: 400 Issue: 1-2 Pages: 171-175
  • DOI: 10.1016/j.apcata.2011.04.029
  • Peer Reviewed
• [Journal Article] Alkene isomerization/enamide-ene and diene metathesis for the construction of indoles, quinolines, benzofurans and chromenes with a chiral cyclopropane substituent (2011)
  • Author(s): Kobayashi, T., Arisawa, M., Shuto, S.
  • Journal Title: Organic & Biomolecular Chemistry Volume: 9 Issue: 4 Pages: 1219-1224
  • DOI: 10.1039/c0ob00597e
  • Peer Reviewed
• [Journal Article] The Actual Active Species of the Sulfur-modified Gold-supported Palladium as a Highly Effective Palladium Reservoir in the Suzuki-Miyaura Coupling (2011)
  • Author(s): Naoyuki Hoshiya, Satoshi Shuto, Mitsuhiro Arisawa
  • Journal Title: Adv.Synth.Catal. Volume: 353 Issue: 5 Pages: 743-748
  • DOI: 10.1002/adsc.201000820
  • Peer Reviewed
• [Journal Article] Design and Synthesis of Conformationally Restricted Indomethacin Analogues that Enhance Doxorubicin Cytotoxicity in Multidrug Resistant Cells without Cyclooxygenase Inhibitory Activity (2011)
  • Author(s): Mitsuhiro Arisawa, Yayoi Kasaya, Tohru Obata, Takuma Sasaki, Mika Ito, Hiroshi Abe, Yoshihiro Ito, Akihito Yamano, Satoshi Shuto
  • Journal Title: ACS Med.Chem.Lett. Volume: 2 Issue: 5 Pages: 353-357
  • DOI: 10.1021/ml100292y
  • Peer Reviewed
• [Journal Article] One-pot Ring-closing Metathesis (RCM)/oxidation by an Assisted Tandem Rutheniumcatalysis for the Synthesis of 2-Quinolones (2011)
  • Author(s): Hiroshige Kato, Tatsuya Ishigame, Nobuhiro Oshima, Ken Shimawaki, Mitsuhiro Arisawa, Satoshi Shuto
  • Journal Title: Adv.Synth.Catal. Volume: 353 Issue: 14-15 Pages: 2676-2680
  • DOI: 10.1002/adsc.201100303
  • Peer Reviewed
• [Journal Article] Synthesis of a series of 3,4-methanoarginines as side-chain conformationally restricted analogues of arginine (2011)
  • Author(s): Mizuki Watanabe, Kazuya Yamaguchi, W.Tang, Keisuke Yoshida, Richard B.Silverman, Mitsuhiro Arisawa, Satoshi Shuto
  • Journal Title: Bioorg.Med.Chem. Volume: 19 Issue: 20 Pages: 5984-5988
  • DOI: 10.1016/j.bmc.2011.08.049
  • Peer Reviewed
• [Presentation] ハイプシン結合RNAアプタマー取得を目的とするハイプシン誘導体の設計と合成 (2015)
  • Author(s): 阿部 敬介, 小黒 明広, 西村 和洋, 市川 哲也, 藤岡 弘道, 有澤 光弘
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学
  • Year and Date: 2015-03-28
• [Presentation] 硫黄修飾金担持型ニッケル触媒の開発とアルキンへの二酸化炭素固定化反応の利用 (2015)
  • Author(s): 谷口 敬寿, 齋藤 望, 星谷 尚亨, 周東 智, 本間 徹生, 藤岡 弘道, 有澤 光弘, 佐藤美洋
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学
  • Year and Date: 2015-03-26
• [Presentation] 硫黄修飾金担持型ニッケル触媒を用いたリガンドフリークロスカップリング反応の開発 (2015)
  • Author(s): 藤木 勝将, 星谷 尚亨, 谷口 敬寿, 周東 智, 藤岡 弘道, 斎藤 望, 佐藤 美洋, 有澤光弘
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学
  • Year and Date: 2015-03-26
• [Presentation] エインメタセシス/異性化/Diels-Alder ワンポット反応の開発 (2015)
  • Author(s): 山下 航平, 藤岡 弘道, 有澤 光弘
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学
  • Year and Date: 2015-03-26
• [Presentation] Ru錯体を用いて調製したRu/S12A7触媒上でのトルエンの水蒸気改質 (2015)
  • Author(s): 飯田肇, 野口和秀, 沼尭氏, 五十嵐哲, 奥村和
  • Organizer: 触媒討論会
  • Place of Presentation: 成蹊大学
  • Year and Date: 2015-03-23
• [Presentation] Ru錯体を前駆体とした担持Ru触媒の調製と触媒作用 ―熱処理温度がRu粒子径に及ぼす影響― (2015)
  • Author(s): 沼尭氏, 小林由紀子, 飯田肇, 奥村和
  • Organizer: 触媒討論会
  • Place of Presentation: 成蹊大学
  • Year and Date: 2015-03-23
• [Presentation] Pd および Ni 触媒によるシクロプロパン第三級炭素上への芳香環導入反応 ―効率的化学空間探索型創薬ライブラリーの構築を目指して― (2014)
  • Author(s): 星谷尚亨,四辻慶佑,小林嵩明,福田 隼,阿部 洋,有澤光弘,周東 智
  • Organizer: 第40回反応と合成の進歩シンポジウム
  • Place of Presentation: 東北大学萩ホール
  • Year and Date: 2014-11-11
• [Presentation] Pd ナノ粒子触媒 SAPd を用いたアリルエステルの脱アリル化反応の開発 (2014)
  • Author(s): 高木耕治,福田 隼,阿部 洋,周東 智,大高 章,有澤光弘
  • Organizer: 第40回反応と合成の進歩シンポジウム
  • Place of Presentation: 東北大学萩ホール
  • Year and Date: 2014-11-11
• [Presentation] Ligand-free Suzuki-Miyaura Coupling with Sulfur-modified Gold-supported Palladium in the Synthesis of a Conformationally-Restricted Cyclopropane Compound Library with Three-Dimensional Diversity (2014)
  • Author(s): Mitsuhiro Arisawa, Takatoshi Sato, Naoyuki Hoshiya, Mohammad Al-Amin, Yuji Kogami and Satoshi Shuto
  • Organizer: The 2nd International Conference on Organometallics and Catalysis
  • Place of Presentation: Todaiji Temple Cultural Center Nara, Japan
  • Year and Date: 2014-10-27
• [Presentation] 硫黄修飾ガラス担持型パラジウムの開発:リガンドフリーBuchwald-Hartwig 反応 (2014)
  • Author(s): XiaoMincen、星谷尚亨、周東 智、藤岡弘道、 有澤光弘
  • Organizer: 第64回 日本薬学会近畿支部総会・大会
  • Place of Presentation: 京都薬科大学
  • Year and Date: 2014-10-11
• [Presentation] 有機金属触媒を用いた機能性分子の創製 (2014)
  • Author(s): 有澤光弘
  • Organizer: 名城大学特別講演会
  • Place of Presentation: 名城大学
  • Year and Date: 2014-10-10
  • Invited
• [Presentation] Ring-closing metathesis (RCM)/1,3-dipolar cycloaddition for the synthesis of isoindolo[2,1-a]quinolone structure dye (2014)
  • Author(s): Mitsuhiro Arisawa
  • Organizer: ETH Zuich-Osaka University Joint-symposium
  • Place of Presentation: 大阪大学基礎工学部Σホール
  • Year and Date: 2014-10-09
  • Invited
• [Presentation] クラウンエーテルを構造指向剤として合成したFAUゼオライトの酸性質 (2014)
  • Author(s): 石橋嵩史, 奥村和, 片田直伸
  • Organizer: 触媒討論会
  • Place of Presentation: 広島大学
  • Year and Date: 2014-09-27
• [Presentation] 物理混合・熱処理によるPdナノ粒子の調製 (2014)
  • Author(s): 奥田章仁, 奥村和, 片田直伸
  • Organizer: 触媒討論会
  • Place of Presentation: 広島大学
  • Year and Date: 2014-09-27
• [Presentation] 金錯体を前駆体とする物理混合・熱処理による担持金ナノ粒子の調製 (2014)
  • Author(s): 川口 侑亮, 奥村和, 片田直伸
  • Organizer: 触媒討論会
  • Place of Presentation: 広島大学
  • Year and Date: 2014-09-26
• [Presentation] Pd0-PdO/USY 触媒による空気中・室温での鈴木カップリング反応 (2014)
  • Author(s): 奥村和, 虫明琢海, 片田直伸
  • Organizer: 触媒討論会
  • Place of Presentation: 広島大学
  • Year and Date: 2014-09-25
• [Presentation] MSE型チタノシリケートTi-YNU-2でのフェノール酸化の活性点構造の考察 (2014)
  • Author(s): 稲垣怜史, 佐々木麻希子, 佐藤裕哉, 奥村和, 窪田好浩
  • Organizer: 触媒討論会
  • Place of Presentation: 広島大学
  • Year and Date: 2014-09-25
• [Presentation] 硫黄修飾ガラス担持型パラジウムの開発:リガン ドフリーBuchwald-Hartwig 反応 (2014)
  • Author(s): 肖王文岑・星谷 尚亨・周東 智・藤岡 弘 道・有澤 光弘
  • Organizer: 第61回有機金属化学討論会
  • Place of Presentation: 九州大学病院キャンパス 医学部 百年講堂
  • Year and Date: 2014-09-25
• [Presentation] Grubbs 触媒を用いたアレンーエンの分子内[2+2]環 化反応:アザビシクロ[3.1.1]ヘプタン骨格の合成 (2014)
  • Author(s): 米重 勇祐・名田 智美・周東 智・ 藤岡 弘道・有澤 光弘
  • Organizer: 第61回有機金属化学討論会
  • Place of Presentation: 九州大学病院キャンパス 医学部 百年講堂
  • Year and Date: 2014-09-24
• [Presentation] 第一原理計算による表面ナノ構造の解析と予測 (2014)
  • Author(s): 石井 晃,藤原 史明,松井 優
  • Organizer: 2014年度精密工学会秋季大会学術講演会
  • Place of Presentation: 鳥取大学
  • Year and Date: 2014-09-16
  • Invited
• [Presentation] ルテニウムカルベン錯体を用いたワンポット反応の開発と新規多環性複素環骨格の構築 (2014)
  • Author(s): 藤居 由基 ・加藤 宏茂・福田 隼・阿部 洋 ・藤岡 弘道 ・周東 智 ・有澤 光弘
  • Organizer: 第 44 回 複素環化学討論会
  • Place of Presentation: 札幌市民ホール
  • Year and Date: 2014-09-11
• [Presentation] 硫黄修飾金に担持した有機合成用金属ナノ粒子触媒の開発 (2014)
  • Author(s): 有澤光弘
  • Organizer: 第11回Spring-8産業利用報告会
  • Place of Presentation: 姫路商工会議所
  • Year and Date: 2014-09-04
  • Invited
• [Presentation] Th - B3 - 341 - Design of reusable Pd catalyst on adsorbed SO4 on graphene and h-BN using DFT calculation for green chemistry (2014)
  • Author(s): Akira Ishii
  • Organizer: ecoss30
  • Place of Presentation: Kervansaray Lara Convention Center, Turkey
  • Year and Date: 2014-09-04
• [Presentation] ゼオライトを担体とした金属ナノ粒子の調製，キャラクタリゼーションと触媒作用 (2014)
  • Author(s): 奥村和
  • Organizer: ゼオライト夏の学校
  • Place of Presentation: 成蹊大学 箱根寮
  • Year and Date: 2014-09-03
  • Invited
• [Presentation] Design of reusable Pd catalyst on adsorbed SO4 on graphene and h-BN using DFT calculation for green chemistry (2014)
  • Author(s): Akira Ishii
  • Organizer: IUMRS-ICA2014
  • Place of Presentation: Fukuoka University
  • Year and Date: 2014-08-25
• [Presentation] 硫黄修飾金に担持したニッ ケルナノ粒子触媒の開発 (2014)
  • Author(s): 藤木勝将、星谷尚之、谷口敬寿、 藤岡弘道、周東智、齋藤望、佐藤美洋、有澤光弘
  • Organizer: 第３４回有機合成若手セミナー「明日の有機合成を担う人のために」
  • Place of Presentation: 大阪大学会館
  • Year and Date: 2014-08-05
• [Presentation] One-Pot Ring-Closing Metathesis (RCM)/1,3-Dipolar Cycloaddition by an Assisted Tandem Ruthenium Catalysis for the Synthesis of an Isoindolo[2,1-a]quinoline Structure Dye (2014)
  • Author(s): Mitsuhiro Arisawa, Yuki Fujii, Hiroshige Kato, Hayato Fukuda, Hiroshi Abe, Hiromichi Fujioka, Satoshi Shuto
  • Organizer: XXVI International Conference on Organometallic Chemistry (ICOMC 2014)
  • Place of Presentation: Royton Sapporo, Sapporo, Japan.
  • Year and Date: 2014-07-14
• [Presentation] レゾルビンE2の安定化を指向した構造活性相関研究 (2014)
  • Author(s): 高倉 夕季 福田 隼 石村 航平 田辺 真人 有澤 光弘 周東 智
  • Organizer: 日本薬学会北海道支部 第141回例会
  • Place of Presentation: 札幌コンベンションセンター
  • Year and Date: 2014-05-24
• [Presentation] レゾルビンE2のシクロプロパン環導入による安定等価体の創製 (2014)
  • Author(s): 高倉夕季
  • Organizer: 日本薬学会第１３４年会
  • Place of Presentation: 熊本大学（熊本県）
• [Presentation] Pdナノパーティクルを用いたC(sp2)-H結合活性化反応によるベンゾトリアゾール骨格の構築 (2014)
  • Author(s): 高木耕治
  • Organizer: 日本薬学会第１３４年会
  • Place of Presentation: 熊本大学（熊本県）
• [Presentation] SAPd触媒を用いたヨウ化アリールへのダブルカルボニル化反応の開発 (2014)
  • Author(s): 谷口敬寿
  • Organizer: 日本薬学会第１３４年会
  • Place of Presentation: 熊本大学（熊本県）
• [Presentation] GABAトランスポーターサブタイプ特異的な新規阻害剤候補化合物の薬理活性評価 (2014)
  • Author(s): 井川ありさ
  • Organizer: 日本薬学会第１３４年会
  • Place of Presentation: 熊本大学（熊本県）
• [Presentation] 疎水性相互作用に基づく機能性核酸の開発 (2013)
  • Author(s): 遠藤秀幸
  • Organizer: 日本薬学会北海道支部第140年会
  • Place of Presentation: 札幌コンベンションセンター（北海道）
• [Presentation] One-pot Ring-Closing Metathesis (RCM)/1,3-Dipolar Cycloaddition by an Assisted Tandem Ruthenium Catalysis for the Synthesis of an ISonidolo[2,1-a]quinoline Structure Dye (2013)
  • Author(s): Mitsuhiro ARISAWA
  • Organizer: International Symposium on Olefin Metathesis and Related Chemistry
  • Place of Presentation: Todaiji-temple Lecture Hall（奈良県）
• [Presentation] One-pot Ring-closing Metathesis (RCM)/1,3-Dipolar Cycloaddition by an Assisted Tandem Ruthenium Catalysis for the Synthesis of Pyrrolo[1,2-a]quinolines (2013)
  • Author(s): Mitsuhiro ARISAWA
  • Organizer: The 3rd International Symposium on Molecular Activation
  • Place of Presentation: Sheraton Steamboat Resort（米国）
  • Invited
• [Presentation] Transition-Metal Nanosazied Palladium Particles for Organic Reaction (2013)
  • Author(s): Naoyuki HOSHIYA
  • Organizer: The 3rd International Symposium on Molecular Activation
  • Place of Presentation: Sheraton Steamboat Resort（米国）
• [Presentation] One-pot Ring-closing Metathesis (RCM)/1,3-Dipolar Cycloaddition by an Assisted Tandem Ruthenium Catalysis for the Synthesis of Pyrrolo[1,2-a]quinolines (2013)
  • Author(s): Mitsuhiro ARISAWA
  • Organizer: 17th International Symposium on Organometallic Chemistry directed toward Organic Synthesis
  • Place of Presentation: Colorado State University（米国）
• [Presentation] Palladium(0)-catalyzed Regioselective Intermolecular Direct Arylation of Tertiary Carbon on Cyclopropane (2013)
  • Author(s): Naoyuki HOSHIYA
  • Organizer: 17th International Symposium on Organometallic Chemistry directed toward Organic Synthesis
  • Place of Presentation: Colorado State University（米国）
• [Presentation] Sulfu-modified Au-supported Palladium-catalyzed Double Carbonylation Reaction under Ligand-Free Conditions (2013)
  • Author(s): Takahisa TANIGUCHI
  • Organizer: 17th International Symposium on Organometallic Chemistry directed toward Organic Synthesis
  • Place of Presentation: Colorado State University（米国
• [Presentation] Development of sulfur-modified Au-supported palladium and its use in medicinal research (2013)
  • Author(s): Koji TAKAGI
  • Organizer: The Sixteenth International Symposium on Relations between Homogeneous and Heterogeneous Catalysis (ISHHC-16)
  • Place of Presentation: Hokkaido University（北海道）
• [Presentation] 硫黄修飾金に担持したパラジウム触媒によるリ ガンドフリー条件でのダブルカルボニル化反応の開発 (2013)
  • Author(s): 谷口 敬寿
  • Organizer: 第 60 回 有機金属化学討論会
  • Place of Presentation: 学習院大学（東京都）
• [Presentation] 光学活性第三級ヨードシクロプロパンとニッケル触媒を用いた鈴木－宮浦カップリング反応の開発 (2013)
  • Author(s): 四辻慶佑
  • Organizer: 第43回複素環化学討論会
  • Place of Presentation: 長良川国際会議場（岐阜県）
• [Presentation] ペプチド性天然物ベラクトシン A をプロトタイプとする高活性非ペプチド性プロテアソーム 阻害剤の創 製:“Scaffold Hopping” に基づく論理的分子設計と合成 (2013)
  • Author(s): 川村周平
  • Organizer: 第39回反応と合成の進歩シンポジウム
  • Place of Presentation: 九州大学医学部百年講堂（福岡県）
• [Presentation] Design and synthesis of indomethacin analogues that inhibit P-glycoprotein and/or multi-drug resistant protein without cox inhibitory activity (2013)
  • Author(s): Mitsuhiro ARISAWA
  • Organizer: Asian Federation for Pharmaceutical Sciences Conference
  • Place of Presentation: Ramada Plaza Jeju Hotel（韓国）
  • Invited
• [Presentation] USYゼオライトの触媒作用と貴金属に対する担体効果 (2013)
  • Author(s): 奥村和
  • Organizer: 第 34 回 触媒学会若手会「夏の研修会」
  • Place of Presentation: 平野屋（愛知県）
  • Invited
• [Presentation] 光学活性ブロモメチレンシクロプロパンを用いる鈴木-宮浦クロスカップリングとTNF-α阻害剤合成への応用 (2012)
  • Author(s): 田辺真人
  • Organizer: 日本薬学会第132年会
  • Place of Presentation: 北海道大学(北海道)
  • Year and Date: 2012-03-30
• [Presentation] アンモニウム塩水溶液処理によるUSYゼオライトでの強酸点の発現およびY型ゼオライトのクラッキング活性と酸強度の相関 (2012)
  • Author(s): 奥村和
  • Organizer: 第109回触媒討論会
  • Place of Presentation: 東京工業大学(東京都)
  • Year and Date: 2012-03-29
• [Presentation] がん細胞の多剤耐性克服作用を有する新規インドール化合物の創製 (2012)
  • Author(s): 名田智美
  • Organizer: 日本薬学会第132年会
  • Place of Presentation: 北海道大学(北海道)
  • Year and Date: 2012-03-29
• [Presentation] 三次元構造制御型Grb2-SH2ドメインリガンドの創製研究 (2012)
  • Author(s): 荒川和人
  • Organizer: 日本薬学会第132年会
  • Place of Presentation: 北海道大学(北海道)
  • Year and Date: 2012-03-29
• [Presentation] DFT calculation for OH group around Pd on S-modified Au(111) (2012)
  • Author(s): Mami Yokoyama
  • Organizer: CRC International Symposium on Green & Sustainable Catalysis : from Theoretical and Fundamental Aspects to Catalyst Design
  • Place of Presentation: 北海道大学触媒研究センター(北海道)
  • Year and Date: 2012-01-26
• [Presentation] DFT calculation for Pd catalyst on S-terminated Au(111) (2011)
  • Author(s): Mami Yokoyama
  • Organizer: 2nd nanotoday CONFERENCE
  • Place of Presentation: Marriott Waikoloa Beach (Hawaii)
  • Year and Date: 2011-12-14
• [Presentation] Acid properties, catalysis and support effects of USY zeolites (2011)
  • Author(s): Kazu Okumura
  • Organizer: International Meeting on Novel Catalyst Design and Surface Science
  • Place of Presentation: 姫路イーグレ(兵庫県)
  • Year and Date: 2011-12-09
• [Presentation] アデノホスチン型新規IP3バイオセンサーの開発 (2011)
  • Author(s): 大浦泰
  • Organizer: 日本薬学会北海道支部第137回例会
  • Place of Presentation: 北海道大学(北海道)
  • Year and Date: 2011-12-03
• [Presentation] Suzuki-Miyaura reactions catalyzed by Pd/USY zeolites (2011)
  • Author(s): Kazu Okumura
  • Organizer: Pre-symposium of C&FC2011
  • Place of Presentation: 龍谷大学・響都ホール(京都府)(招待講演)
  • Year and Date: 2011-12-02
• [Presentation] メタンを還元剤としたPd/モルデナイト触媒によるNO還元反応-シリカCVDによる耐久性の向上- (2011)
  • Author(s): 吉田浩之
  • Organizer: 第41回石油化学討論会
  • Place of Presentation: 山口県教育会館(山口県)
  • Year and Date: 2011-11-10
• [Presentation] Synthesis of 5'-Modified Adenophostin A as a Biological Tool for Investigating IP_3-Mediated Ca_<2+>-Mobilization (2011)
  • Author(s): 大浦泰
  • Organizer: 第38回国際核酸化学シンポジウム
  • Place of Presentation: 北海道大学(北海道)
  • Year and Date: 2011-11-10
• [Presentation] 三次元多用型配座制御法に基づくペプチドミメチィックの設計:メラノコルチン受容体リガンドの創製 (2011)
  • Author(s): 水野彰
  • Organizer: 第37回反応と合成のシンポシンポジウム
  • Place of Presentation: あわぎんホール(徳島県)
  • Year and Date: 2011-11-07
• [Presentation] 標的たんぱく質同定用バイオツールとしての4"分岐型サイクリックADPカーボサイクリックリボースの合成及び生物活性 (2011)
  • Author(s): 佐藤隆俊
  • Organizer: 第41回複素環化学討論会
  • Place of Presentation: 熊本市民会館(熊本県)
  • Year and Date: 2011-10-22
• [Presentation] アンモニウム塩水溶液処理によるUSYゼオライトの強酸点と高いアルカンクラッキング活性の発現 (2011)
  • Author(s): 奥村和
  • Organizer: 第108回触媒討論会
  • Place of Presentation: 北見工業大学(北海道)
  • Year and Date: 2011-09-20
• [Presentation] NH3 IRMS-TPD法によるUSYゼオライトの酸性質解析 (2011)
  • Author(s): 奥村和
  • Organizer: 第五回触媒道場
  • Place of Presentation: 関西セミナーハウス(京都府)(招待講演)
  • Year and Date: 2011-09-09
• [Presentation] 硫黄修飾金に担持したパラジウムSAPdによるリガンド非存在化でのBuchwald-Hartwig反応 (2011)
  • Author(s): アルアミン モハンマド
  • Organizer: 第58回有機金属化学討論会
  • Place of Presentation: 名古屋大学東山キャンパス(愛知県)
  • Year and Date: 2011-09-07
• [Presentation] DFT calculation for Pd catalyst on S-modified Au(111) (2011)
  • Author(s): Mami Yokoyama
  • Organizer: ISFM2011
  • Place of Presentation: 東北大学片平キャンパス(宮城県)
  • Year and Date: 2011-08-04
• [Presentation] GABAトランスポーターサブタイプ特異的な新規阻害薬候補化合物の薬理活性評価 (2011)
  • Author(s): 早川航
  • Organizer: 16th International Uuion of Pure and Applied Chemistry-Organometallic Chemistry toward Organic Synthesis (IUPAC-OMCOS 16)
  • Place of Presentation: Shanghai International Convention Center (China)
  • Year and Date: 2011-07-25
• [Presentation] Ruthenium-Catalyzed Ccycloisomerization of 1,3-Diene with Alkene of an N-Dienyl-2-vinylaniline Leading to a 3-Exomethylene-2-vinylindole and its Application to the synthesis of (±)-Cinchonanminone (2011)
  • Author(s): 有澤光弘
  • Organizer: 16th International Uuion of Pure and Applied Chemistry- Organometallic Chemistry toward Organic Synthesis (IUPAC-OMCOS 16)
  • Place of Presentation: Shanghai International Convention Center (China)
  • Year and Date: 2011-07-25
• [Presentation] Suzuki-Miyaura Cross Copling Using Chiral Bromomethylenecyclopropane (2011)
  • Author(s): 田辺真人
  • Organizer: 16th International Uuion of Pure and Applied Chemistry-Organometallic Chemistry toward Organic Synthesis (IUPAC-OMCOS 16)
  • Place of Presentation: Shanghai International Convention Center (China)
  • Year and Date: 2011-07-25
• [Presentation] DFT calculation for Pd catalyst on S-modified Au(111) (2011)
  • Author(s): Mami Yokoyama
  • Organizer: ICSFI-13
  • Place of Presentation: The Institute of Physics of the Academy of Sciences of the Czech Republic(Praha)
  • Year and Date: 2011-07-04
• [Presentation] 光学活性ブロモメチレンシクロプロパンを用いる鈴木-宮浦クロスカップリング (2011)
  • Author(s): 田辺真人
  • Organizer: 第23回万有札幌シンポジウム
  • Place of Presentation: 北海道大学(北海道)
  • Year and Date: 2011-07-02
• [Presentation] Pd/USYとNb-W積層ファイバーの構造と触媒作用 (2011)
  • Author(s): 奥村和
  • Organizer: ワークショップ「ナノ粒子触媒の構造制御と表面化学」
  • Place of Presentation: 定山渓万世閣ホテルミリオーネ(北海道)
  • Year and Date: 2011-06-29
• [Presentation] DFT calculation for green chemical catalyst with hydroxyl group supported on S-terminated GaN(0001) and GaAs(001) (2011)
  • Author(s): A.Ishii
  • Organizer: APWS2011
  • Place of Presentation: 鳥羽国際ホテル(三重県)
  • Year and Date: 2011-05-23
• [Presentation] DFT calculation for OH group around Pd on S-modified Au(111) (2011)
  • Author(s): Mami Yokoyama
  • Organizer: TNT2011
  • Place of Presentation: Hotel lberostar anthelia (Spain)
• [Presentation] クロスカップリング反応による芳香環直結型光学活性三置換シクロプロパンの合成
  • Author(s): 四辻 慶佑
  • Organizer: 25周年記念 万有札幌シンポジウム 未来を拓く創造有機化学
  • Place of Presentation: 北海道大学工学部オープンホール（北海道）
• [Presentation] Structure, acid property, and catalytic activity of hierarchical ultrastable Y
  • Author(s): Kazu Okumura, Jota Oyama, Naonobu Katada
  • Organizer: 7th International Symposium on Acid-Base Catalysis
  • Place of Presentation: TKP ガーデンシティ品川
• [Presentation] Ring-opening of tetrahydrofuran to butyraldehyde catalyzed by acid sites
  • Author(s): Satoshi Kamiguchi, Kazu Okumura, Sayoko Nagashima, Teiji Chihara
  • Organizer: 7th International Symposium on Acid-Base Catalysis
  • Place of Presentation: TKP ガーデンシティ品川
• [Presentation] Structure and catalysis of layered NbW oxide constructed by self-assembly of nanofibers
  • Author(s): Kazu Okumura, Soichiro Ishida, Naonobu Katada
  • Organizer: 8th International Mesostructured Materials Symposium
  • Place of Presentation: 淡路夢舞台国際会議場
• [Presentation] Formation and catalysis of thermally stable gold nanoparticles on ultrastable Y zeolites
  • Author(s): Kazu Okumura, Chika Murakami, Takashi Sanada, Naonobu Katada
  • Organizer: The Sixteenth International Symposium on Relations between
  • Place of Presentation: 北海道大学
• [Presentation] USYゼオライトの触媒作用と貴金属に対する担体効果
  • Author(s): 奥村和
  • Organizer: 第112回触媒討論会
  • Place of Presentation: 秋田大学
  • Invited
• [Presentation] USYゼオライトの触媒作用と貴金属に対する担体効果
  • Author(s): 奥村和
  • Organizer: 第22回グリーンケミストリーフォーラム
  • Place of Presentation: 大阪大学
  • Invited
• [Presentation] ゼオライトおよび金属酸化物の酸性質・触媒作用と貴金属に対する担体効果
  • Author(s): 奥村和
  • Organizer: JACI研究会
  • Place of Presentation: 新化学技術推進協会
  • Invited
• [Presentation] Suzuki Coupling Reactions Catalyzed by Pd/USY at Room Temperature
  • Author(s): Kazu Okumura, Takumi Mushiake, Naonobu Katada
  • Organizer: Novel Designed Surface and Catalysis for Greener Future: C&FC Pre-Symposium in Himeji
  • Place of Presentation: イーグレ姫路
• [Presentation] Preparation and catalyst activity of high dispersion metal which were supported to zeolite with the physical mixed method
  • Author(s): Takumi Mushiake, Akihiko Okuda, Kazu Okumura, Naonobu Katada
  • Organizer: Novel Designed Surface and Catalysis for Greener Future: C&FC Pre-Symposium in Himeji
  • Place of Presentation: イーグレ姫路
• [Presentation] XAFSによる金属触媒の構造および状態解析
  • Author(s): 奥村和
  • Organizer: 触媒学会第23回キャラクタリゼーション講習会
  • Place of Presentation: 九州大学
  • Invited
• [Presentation] PdO/USY触媒による空気中・室温での鈴木カップリング反応
  • Author(s): 奥村和・虫明琢海・片田直伸
  • Organizer: 第113回触媒討論会
  • Place of Presentation: ロワジールホテ豊橋
• [Presentation] SO4/Au(111) for support of Pd catalyst using DFT calculation
  • Author(s): Akira Ishii
  • Organizer: ICSFS16
  • Place of Presentation: The University of Genoa（Italy)
• [Presentation] DFT calculation for Pd catalyst on SO4/Au(111)
  • Author(s): Mami Yokoyama
  • Organizer: ＧＯＬＤ2012
  • Place of Presentation: 京王プラザホテル（東京都）
• [Presentation] Theory and Experiment of Palladium Catalysis for Ligand-free Coupling Reaction on Sulfur-modified Au
  • Author(s): Akira Ishii
  • Organizer: SSNS'13
  • Place of Presentation: ホテル樹林（山形市）
  • Invited
• [Presentation] Evolution of Strong Acidity in Ammonium-treated USY Zeolites and Correlation between Acid Strength and the Activation Energy of Alkane Cracking in Y-type Zeolites
  • Author(s): Kazu Okumura
  • Organizer: ZMPC2012
  • Place of Presentation: アステールプラザ（広島市）
• [Presentation] Detection of the local structure related to strong acid sites for high-alkane-cracking on ammonium-treated USY zeolite using 27Al and 17O MQMAS NMR
  • Author(s): Takashi Sanada
  • Organizer: ZMPC2012
  • Place of Presentation: アステールプラザ（広島市）
• [Presentation] Spontaneous Dispersion of Gold Nanoparticles Loaded on USY Zeolites as Analyzed by XAFS, XRD, and TEM
  • Author(s): Chika Murakami
  • Organizer: ZMPC2012
  • Place of Presentation: アステールプラザ（広島市）
• [Presentation] Suppression of Pd dissolution and side reaction in Suzuki coupling reaction catalyzed by Pd/USY
  • Author(s): Takanori Osaki
  • Organizer: ZMPC2012
  • Place of Presentation: アステールプラザ（広島市）
• [Presentation] Generation of nanoparticles of Y-type zeolites during treatment of USY zeolites with an aqueous solution of ammonium nitrate
  • Author(s): Jota Ohyama
  • Organizer: ZMPC2012
  • Place of Presentation: アステールプラザ（広島市）
• [Presentation] Relationship among Brønsted Acid Strength, Activation Energy and Pre-exponential Factor for Cracking of Linear Alkanes on Zeolitic and Non-zeolitic Solid Acid Catalysts
  • Author(s): Satoko Sota
  • Organizer: ZMPC2012
  • Place of Presentation: アステールプラザ（広島市）
• [Presentation] Spontaneous dispersion of gold nanoparticles on USY zeolites
  • Author(s): Kazu Okumura
  • Organizer: 15th International Congress on Catalysis (ICC)
  • Place of Presentation: International Congress Center（Germany)
• [Presentation] Formation of nanometer-sized Au particles on USY zeolites under hydrogen atmosphere
  • Author(s): Kazu Okumura
  • Organizer: GOLD2012
  • Place of Presentation: 京王プラザホテル（東京都）
• [Presentation] Y型ゼオライトを担体とする高分散Au触媒の調製と触媒作用
  • Author(s): 村上智郁
  • Organizer: 第110回触媒討論会
  • Place of Presentation: 九州大学（福岡市）
• [Presentation] Pd/USY触媒を用いた鈴木カップリング反応とPd溶出率の調査
  • Author(s): 大崎隆典
  • Organizer: 第42回石油・石油化学討論会
  • Place of Presentation: 秋田キャッスルホテル（秋田市）
• [Presentation] USYゼオライトのアンモニウム塩処理によるナノ結晶生成とその触媒作用
  • Author(s): 大山丈太
  • Organizer: 第28回ゼオライト研究発表会
  • Place of Presentation: タワーホール船堀（東京都）
• [Presentation] ゼオライトのイオン交換サイトを利用した高分散貴金属触媒の調製と触媒作用
  • Author(s): 奥村和
  • Organizer: 第14回規則性多孔体セミナー
  • Place of Presentation: 鳥取大学（鳥取市）
  • Invited
• [Presentation] 強酸点を有するUSYゼオライトの調製・触媒作用と担体効果
  • Author(s): 奥村和
  • Organizer: 第9回触媒相模セミナー
  • Place of Presentation: 相模中央研究所（綾瀬市）
  • Invited
• [Presentation] Pd/USY触媒を用いた鈴木カップリング反応
  • Author(s): 岡本洋貴
  • Organizer: 兵庫県立大学Cat-on-cat新規表面反応研究センターシンポジウム2012
  • Place of Presentation: 兵庫県立先端科学技術支援センター（赤穂郡）
• [Presentation] 芳香環直結型光学活性三置換シクロプロパン合成法の開発
  • Author(s): 四辻慶佑
  • Organizer: 第138回日本薬学会北海道支部支部例会 （第58回北海道薬学大会）
  • Place of Presentation: 札幌コンベンションセンター（札幌市）
• [Presentation] Structure-Activity Relationship Study of Unnatural cis-Isomer of Belactosin A, a Potent Proteasome Inhibitor
  • Author(s): 川村周平
  • Organizer: 第24回万有札幌シンポジウム
  • Place of Presentation: 北海道大学（札幌市）
• [Presentation] One-Pot Ring-Closing Metathesis (RCM)/Oxidation by an Assisted Tandem Ruthenium Catalysis for the Synthesis of 2-Quinolones
  • Author(s): 有澤光弘
  • Organizer: 2012 "Organometallic Chemistry" Gordon Research Conference
  • Place of Presentation: Salve Regina University（USA）
• [Presentation] One-pot Ring-closing Metathesis (RCM)/1,3-Dipolar Cycloaddition by an Assisted Tandem Ruthenium Catalysis for the Synthesis of Pyrrolo[1,2-a]quinolines
  • Author(s): 藤居由基
  • Organizer: 第59回有機金属化学討論会
  • Place of Presentation: 大阪大学（吹田市）
• [Presentation] Microwave-Assisted Suzuki-Miyaura Cross Coupling Reaction with a Low-Leaching and Highly Recyclable Gold-Supported
  • Author(s): Mohanmad Al-Amin
  • Organizer: 第59回有機金属化学討論会
  • Place of Presentation: 大阪大学（吹田市）
• [Presentation] 光学活性メチレンシクロプロパンを鍵ユニットとする低分子TNF-alpha阻害剤の創製研究
  • Author(s): 田辺真人
  • Organizer: 第42回複素環化学討論会
  • Place of Presentation: 京都テルサ（京都市）
• [Presentation] リガンドフリーPdクロスカップリングの開発と創薬研究への応用
  • Author(s): 有澤光弘
  • Organizer: 第3８回反応と合成のシンポシンポジウム
  • Place of Presentation: タワーホール船堀（東京都）
• [Presentation] Synthesis of novel indole derivatives as potent cancer MDR modulators in cancer chemotherapy.
  • Author(s): Tomomi Nada
  • Organizer: The 12th international Kyoto conference on new aspects of organic chemistry (OKCOC-12)
  • Place of Presentation: リーガロイヤルホテルホテル京都（京都市）
• [Presentation] A cross coupling for preparing chiral trisubstituted arylcyclppropanes
  • Author(s): Keisuke Yotsuji
  • Organizer: The 12th international Kyoto conference on new aspects of organic chemistry (OKCOC-12)
  • Place of Presentation: リーガロイヤルホテルホテル京都（京都市）
• [Presentation] 分指標的低分子化合物の創製を指向した新規三次元構造制御ユニットの開発
  • Author(s): 小國泰生
  • Organizer: 第139回日本薬学会北海道支部支部例会
  • Place of Presentation: 北海道大学（札幌市）
• [Presentation] ペプチドの多様な立体配座を模倣する配座制御型ペプチドミメティクスの創製
  • Author(s): 水野 彰
  • Organizer: 日本薬学会第133年会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] GAT-3選択的阻害を目的とした新規GABA配座制限誘導体の合成
  • Author(s): 末政亮大
  • Organizer: 日本薬学会第133年会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] ３次元構造制御型Grb2-SH2ドメインリガンドの創製研究
  • Author(s): 荒川和人
  • Organizer: 日本薬学会第133年会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] ルテニウム触媒を用いた閉環メタセシス(RCM)-[3+2]環化付加ワンポット反応
  • Author(s): 藤居由基
  • Organizer: 日本薬学会第133年会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Book] 表面科学 (2014)
  • Author(s): 奥村和
  • Total Pages: 6
  • Publisher: QXAFS 法によるUSY ゼオライトを担体としたパラジウムの動的挙動解析
• [Book] Palladium-Catalyzed Coupling Reactions, A. Molnáred. (2013)
  • Author(s): 奥村和
  • Total Pages: 26
  • Publisher: Wiley-vch
• [Remarks] 活性点の精密設計による高活性・高選択的触媒の創成
  • URL: http://katalab.org/okmr/okmr.htm
• [Remarks] 創薬有機化学研究室
  • URL: http://www.pharm.hokudai.ac.jp/yuuki/index.html
• [Remarks]
  • URL: http://www.pharm.hokudai.ac.jp/yuuki/index.html
• [Patent(Industrial Property Rights)] 触媒金属ナノ粒子含有複合体及びその利用 (2014)
  • Inventor(s): 有澤光弘，周東 智，星谷尚亨，新 井聡史
  • Industrial Property Rights Holder: 有澤光弘，周東 智，星谷尚亨，新 井聡史
  • Industrial Property Rights Type: 特許
  • Filing Date: 2014-03-28
  • Overseas
• [Patent(Industrial Property Rights)] ゼオライト触媒およびその製造方法 (2012)
  • Inventor(s): 大山丈太、奥村和
  • Industrial Property Rights Holder: 鳥取大学
  • Industrial Property Rights Type: 特許
  • Filing Date: 2012-11-22
• [Patent(Industrial Property Rights)] USYゼオライトを担体とした自発的高分散化による金ナノ粒子の調製方法、金ナノ粒子 (2012)
  • Inventor(s): 奥村和・村上智郁・小山哲矢
  • Industrial Property Rights Holder: 鳥取大学
  • Industrial Property Number: 2012-043861
  • Filing Date: 2012-02-29