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Comparison of endrine disruption activities of urban wastewater by reporter gene assay considering difference in speices sensitivities

Research Project

Project/Area Number 23254003
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Risk sciences of radiation/Chemicals
Research InstitutionKyoto University

Principal Investigator

TANAKA Hiroaki  京都大学, 工学(系)研究科(研究院), 教授 (70344017)

Co-Investigator(Kenkyū-buntansha) YAMASHITA Naoyuki  京都大学, 大学院・工学研究科, 講師 (90391614)
NAKADA Norihide  京都大学, 大学院・工学研究科, 助教 (00391615)
IHARA Masaru  京都大学, 大学院・工学研究科, CREST研究員 (70450202)
IGUCHI Taisen  大学共同利用機関, 法人自然科学研究機構, 教授 (90128588)
MIYAGAWA Shiniti  大学共同利用機関, 法人自然科学研究機構, 助教 (30404354)
NAGAE Masaki  長崎大学, 環境科学部, 准教授 (00315227)
YASOJIMA Makoto  京都大学, 大学院・工学研究科, 特定准教授 (10541021)
VIMAL Kumar  京都大学, 工学(系)研究科(研究院), 研究員 (00605230)
VIMAL Kumar  京都大学, 工学研究科, GCOE研究院
Co-Investigator(Renkei-kenkyūsha) JOHNSON Andrew  Center for Ecology and Hydrology, Professor
JUERGENS Monika D.  Center for Ecology and Hydrology Scientist, Scientist
ZHANG Jinson  深圳水務集団, 総工程師, 教授
HAN Inhsup  韓国ソウル市立大学, 環境工学科, 教授
KIM Ilho  韓国建設技術院, 主任研究員
HANAMOTO Seiya  京都大学, 特定研究員 (10727580)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥53,170,000 (Direct Cost: ¥40,900,000、Indirect Cost: ¥12,270,000)
Fiscal Year 2013: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2012: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2011: ¥32,110,000 (Direct Cost: ¥24,700,000、Indirect Cost: ¥7,410,000)
Keywords海外調査 / エストロゲン / 医薬品類 / エストロゲン様作用 / 抗エストロゲン作用 / 下水処理場 / 河川 / モデル / 海外現地調査 / 英国 / 韓国 / 中国 / 下水処理 / エストロゲン エストロゲン / 生理活性物質 / 内分泌かく乱 / 下水処理水 / レポータージーンアッセイ / 流域比較 / 生物多様性
Research Abstract

Bioactive activities and compounds such as pharmaceuticals, personal care products as well as estrogens of sewage, treated sewage, and receiving water were compared among Japan, United Kingdom, China and Korea whose sewerage coverage levels are diffrent through field surveys . River basin information was collected and the fates of the bioactive compounds in river trnsformation process were modeled to estimate their sources and to predict future trends of the river basins. Further, reporter gene assays emplolying estrogen recepters derived from diffrent fish speices and human were adapted to enmvironmental water samples. The samples collected in the UK, China and Korea were measured with the developed assay.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (73 results)

All 2014 2013 2012 2011 Other

All Journal Article (23 results) (of which Peer Reviewed: 20 results,  Open Access: 1 results) Presentation (46 results) (of which Invited: 5 results) Book (1 results) Remarks (3 results)

  • [Journal Article] Elevated risk from estrogens in the Yodo River basin (Japan) in winter and ozonation as a management option2014

    • Author(s)
      V. Kumar, S. Hanamoto, A. C. Johnson, N. Yamashita, N. Nakada, H. Tanaka
    • Journal Title

      Environ. Aci. Process Impacts

      Volume: 16 Pages: 232-238

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] Differing species responsiveness of estrogenic contaminants in fish is conferred by the ligand binding domain of the estrogen receptor2014

    • Author(s)
      Miyagawa, S., Lange, A., Hirakawa, I., Tohyama, S., Ogino, Y., Mizutani, T., Kagami, Y., Kusano, T., Ihara, M., Tanaka, H., Tatarazako, N., Ohta, Y., Katsu, Y., Tyler, C.R. and Iguchi, T.
    • Journal Title

      Environ. Sci. Technol.

      Volume: 未定 Issue: 9 Pages: 5254-5263

    • DOI

      10.1021/es5002659

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Verification of responses of Japanese medaka (Oryzias latipes) to antiandrogens, vinclozolin and flutamide, in short-term assays2014

    • Author(s)
      Nakamura, A., Takanobu, H., Tamura, I., Yamamuro, M., Iguchi, T. and Tatarazako, N.
    • Journal Title

      J. Appl. Toxicol.,

      Volume: 35 Issue: 5 Pages: 545-553

    • DOI

      10.1002/jat.2934

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modeling the photochemical attenuation of down-the-drain chemicals during river transport by stochastic methods and field measurements of pharmaceuticals and personal care products, Environ2013

    • Author(s)
      S. Hanamoto, N. Nakada, N. Yamashita, H. Tanaka
    • Journal Title

      Sci. Technol

      Volume: 47 Pages: 13571-13577

    • Related Report
      2013 Final Research Report
  • [Journal Article] Modeling the Photochemical Attenuation of Down-the-Drain Chemicals during River Transport by Stochastic Methods and Field Measurements of Pharmaceuticals and Personal Care Products2013

    • Author(s)
      Hanamoto, S., Nakada, N., Yamashit a, N., Tanaka, H.
    • Journal Title

      Environmental Science and Technology

      Volume: 47 Issue: 23 Pages: 13571-13577

    • DOI

      10.1021/es4035478

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishment of transactivation assay systems using fish, amphibian, reptilian and human thyroid hormone receptors2013

    • Author(s)
      Oka, T., Mitsui-Watanabe, N., Tatarazako, N., Onishi, Y., Katsu, Y., Miyagawa, S., Ogino, Y., Yatsu, R., Kohno, S., Takase, M., Kawashima, Y., Aoki, Y., Guillette, L.J.Jr. and Iguchi, T.
    • Journal Title

      J. Appl. Toxicol

      Volume: 33 Issue: 9 Pages: 991-1000

    • DOI

      10.1002/jat.2825

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Developmental disorders and altered gene expression in the tropical clawed frog (Silurana tropicalis) exposed to 17-ethinylestradiol2013

    • Author(s)
      Hirakawa, I., Miyagawa, S., Mitsui, N., Miyahara, M., Onishi, Y., Kagami, Y., Kusano, T., Takeuchi, T., Ohta, Y. and Iguchi, T.
    • Journal Title

      J. Appl. Toxicol

      Volume: 33 Issue: 9 Pages: 1001-1010

    • DOI

      10.1002/jat.2836

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase distribution and removal of pharmaceuticals and personal care products during anaerobic sludge digestion2013

    • Author(s)
      Takashi Azuma, Norihide Nakada, Naoyuki Yamashita, Hiroaki Tanaka
    • Journal Title

      Journal of Hazardous Materials

      Volume: 260C Pages: 305-312

    • DOI

      10.1016/j.jhazmat.2013.05.032

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mass balance of anti-influenza drugs discharged into the Yodo River system, Japan, under an influenza outbreak2013

    • Author(s)
      Takashi Azuma, Norihide Nakada, Naoyuki Yamashita, Hiroaki Tanaka
    • Journal Title

      Chemosphere

      Volume: 93 Issue: 9 Pages: 1672-7

    • DOI

      10.1016/j.chemosphere.2013.05.025

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phytoremediation of 4,4’-thiodiphenol (TDP) and other bisphenol derivatives by Portulaca oleracea cv.2013

    • Author(s)
      Okuhata, H.
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: 115 Issue: 1 Pages: 55-57

    • DOI

      10.1016/j.jbiosc.2012.08.025

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Endocrine Disrupting Activity and Interspecies Sensitivity of Wastewater : Evaluation by Reporter Gene Assay using Estrogen Receptor-α Derived from Multi-species2012

    • Author(s)
      Ihara M, M. Ohno, V. Kumar, M. Narumiya, S. Hanamoto, N. Nakada, N. Yamashita, S. Miyagawa, T. Iguchi, H. Tanaka
    • Journal Title

      Proceedings of IWA World Water Congress & Exhibition in Busan 2012

    • Related Report
      2013 Final Research Report
  • [Journal Article] De-conjugation behavior of conjugated estrogens in the raw sewage, activated sludge and river water2012

    • Author(s)
      Kumar, V
    • Journal Title

      Journal of Hazardous Materials

      Volume: 227-228 Pages: 49-54

    • DOI

      10.1016/j.jhazmat.2012.04.078

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 流水保全水路と河川における医薬品類の減衰の比較2012

    • Author(s)
      花本征也
    • Journal Title

      環境工学研究論文集

      Volume: 49 Pages: 193-203

    • NAID

      130004962397

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Occurrence of Pharmaceuticals and Personal Care Products in Aquatic Environment around Shenzhen: Comparison of Shenzhen and Japan2012

    • Author(s)
      S. Hanamoto
    • Journal Title

      Proceedings of IWA World Water Congress & Exhibition in Busan

      Volume: 2012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Endocrine Disrupting Activity and Interspecies Sensitivity of Wastewater: Evaluation by Reporter Gene Assay using Estrogen Receptor-α Derived from Multi-species2012

    • Author(s)
      Ihara M
    • Journal Title

      Proceedings of IWA World Water Congress & Exhibition in Busan

      Volume: 2012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative responsiveness to natural and synthetic estrogens of fish species commonly used in the laboratory and field monitoring2012

    • Author(s)
      Lange A, Katsu Y, Miyagawa S, Ogino Y, Urushitani H, Kobayashi T, Hirai T, Shears JA, Nagae M, Yamamoto J, Ohnishi Y, Oka T, Tatarazako N, Ohta Y, Tyler CR, Iguchi T
    • Journal Title

      Aquatic Toxicology

      Volume: 109 Pages: 250-258

    • DOI

      10.1016/j.aquatox.2011.09.004

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gene expression profiles in the testis associated with testis-ova in adult Japanese medaka exposed to 17-ethinylestradiol2012

    • Author(s)
      Hirakawa, I., Miyagawa, S., Katsu, Y., Kagami, Y., Tatarazako, N., Kobayashi, T., Kusano, T., Mizutani, T., Ogino, T., Ohta, Y., Iguchi, T.
    • Journal Title

      Chemosphere

      Volume: 87 Issue: 7 Pages: 668-674

    • DOI

      10.1016/j.chemosphere.2011.12.047

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cloning, expression and functional characterization of carp Cyprinus carpio estrogen receptors and their differential activations by estrogens2011

    • Author(s)
      Katsu, Y., Lange, A., Miyagawa, S., Urushitani, H., Tatarazako, N., Kawashima, Y., Tyler, C.R., Iguchi, T.
    • Journal Title

      J.Appl.Toxicol.

      Volume: 33 Issue: 1 Pages: 41-49

    • DOI

      10.1002/jat.1707

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Estrogen receptors in medaka (Oryzias latipes) and estrogenic environmental contaminants : An in vitro-in vivo correlation2011

    • Author(s)
      Charkraborty, T., Katsu, Y., Zhou, L.Y., Miyagawa, S., Nagahama, Y. and Iguchi, T
    • Journal Title

      J. Steroid Biochem. Mol. Biol.

      Volume: 123 Issue: 3-5 Pages: 115-121

    • DOI

      10.1016/j.jsbmb.2010.11.015

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential expression of three estrogen receptor subtype mRNAs in gonads and liver from embryos to adults of the medaka, Oryzias latipes2011

    • Author(s)
      Charkraborty, T., Shibata, Y., Zhou, L.Y., Katsu, Y., Iguchi, T. and Nagahama, Y
    • Journal Title

      Mol. Cell. Endocrinol

      Volume: 333 Issue: 1 Pages: 47-54

    • DOI

      10.1016/j.mce.2010.12.002

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Implications of persistent exposure to treated wastewater effluent for breeding in wild roach (Rutilus rutilus) populations2011

    • Author(s)
      Lange, A., Paull, G.C., Hamilton, P.B., Iguchi, T., Tyler, C.R.
    • Journal Title

      Environ.Sci.Technol.

      Volume: 45 Issue: 4 Pages: 1673-1679

    • DOI

      10.1021/es103232q

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] How seasonality affects the flow of estrogens and their conjugates in one of Japan's most populous catchments2011

    • Author(s)
      V.Kumar, N.Nakada, N.Yamashita, A.C.Johnson, H.Tanaka
    • Journal Title

      Environmental Pollution

      Volume: 159 Issue: 10 Pages: 2906-2912

    • DOI

      10.1016/j.envpol.2011.04.038

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The arrival and discharge of conjugated estrogens from a range of different sewage treatment plants in the UK2011

    • Author(s)
      Kumar, V., Nakada, N., Yasojima, M., Yamashita, N., Johnson, A.C., Tanaka, H.
    • Journal Title

      Chemosphere

      Volume: 82 Issue: 8 Pages: 1124-1128

    • DOI

      10.1016/j.chemosphere.2010.11.040

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Fate of endocrine disrupting chemicals and emerging contaminants in the environment and their remediation2013

    • Author(s)
      H. TANAKA, et al.
    • Organizer
      15th Annual Scientific Workshop of UK-Japan Co-operation for Research on Endocrine Disrupters in the Aquatic Environment
    • Place of Presentation
      Nagoya
    • Year and Date
      2013-12-09
    • Related Report
      2013 Final Research Report
  • [Presentation] 河川流下過程における医薬品類の光分解に関する研究2013

    • Author(s)
      花本征也, 中田典秀, 山下尚之, 田中宏明
    • Organizer
      第35回京都大学環境衛生工学研究会シンポジウム
    • Place of Presentation
      京都、京都大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] 膜を用いた下水再生処理におけるエストロゲン様作用、抗エストロゲン作用の変化2013

    • Author(s)
      井原賢、大野満理子、李相重、Vimal Kumar、成宮正倫、花本征也、中田典秀、山下尚之、高畠寛生、小林憲太郎、田中宏明、田中祐之、宮川信一、井口泰泉、田中宏明
    • Organizer
      第35回京都大学環境衛生工学研究会シンポジウム
    • Place of Presentation
      京都、京都大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] 淀川水系における抗がん剤成分の挙動把握2013

    • Author(s)
      東剛志、井ノ山智美、寺西裕亮、石打浩隆、山岡美里、三野芳紀、中田典秀、,山下尚之、田中宏明
    • Organizer
      第35回京都大学環境衛生工学研究会シンポジウム
    • Place of Presentation
      京都、京都大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fate and occurrence of endocrine disrupting chemicals and emerging contaminants in the water environment and STP and their control2012

    • Author(s)
      H. Tanaka, et al.
    • Organizer
      14th Annual Scientific Workshop, UK-Japan Co-operation for Research on Endocrine Disrupters in the Aquatic Environment
    • Place of Presentation
      ウインザ,英国
    • Year and Date
      2012-10-31
    • Related Report
      2013 Final Research Report
  • [Presentation] 水環境保全に向けた微量化学物質の制御とその分析2012

    • Author(s)
      田中宏明
    • Organizer
      第55回日本環境化学会講演会
    • Place of Presentation
      タワーホール船堀(東京都)(招待講演)
    • Year and Date
      2012-02-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 淀川におけるPPCPs汚染と対策技術2012

    • Author(s)
      田中宏明
    • Organizer
      京都大学GCOE水処理技術に関する国際シンポジウム
    • Place of Presentation
      京都大学桂キャンパス(京都市)(招待講演)
    • Year and Date
      2012-02-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 微量化学物質による水環境問題とは?~内分泌かく乱物質から医薬品まで~2012

    • Author(s)
      田中宏明
    • Organizer
      第57回日本水環境学会セミナー「微量化学物質による水環境問題の最新動向」
    • Place of Presentation
      自動車会館大会議室(東京都)(招待講演)
    • Year and Date
      2012-01-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] イトヨ腎臓での男性ホルモン刺激によるスピギン合成にはARαが必須である2011

    • Author(s)
      長江真樹, 松尾昴, 瀬川卓也, 東藤孝, 勝義直, 井口泰泉, Alexander P.Scott, Ioanna Katsiadaki
    • Organizer
      第14回環境ホルモン学会研究発表会
    • Place of Presentation
      東京大学山上会館(東京都)
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] トビハゼを用いた干潟における環境ホルモン汚染の影響評価2011

    • Author(s)
      鈴木絢子, 長江真樹, 征矢野清
    • Organizer
      第14回環境ホルモン学会研究発表会
    • Place of Presentation
      東京大学山上会館(東京都)
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 下水高度処理による、エストロゲン・抗エストロゲン様作用の変化2011

    • Author(s)
      井原賢、大野満理子、Vimal Kumar、成宮正倫、花本征也、中田典秀、山下尚之、加藤康弘、青木未知子、宮川信一、井口泰泉、田中宏明
    • Organizer
      第14回環境ホルモン学会研究発表会
    • Place of Presentation
      東京大学山上会館(東京都)
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 種間差を考慮したレポータージーンアッセイによる、下水のエストロゲン様作用および抗エストロゲン様作用の評価2011

    • Author(s)
      大野満理子、井原賢、Vimal Kumar、成宮正倫、花本征也、中田典秀、山下尚之、宮川信一、井口泰泉、田中宏明
    • Organizer
      第14回環境ホルモン学会研究発表会
    • Place of Presentation
      東京大学山上会館(東京都)
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Evaluation of the endocrine disrupting activity of wastewater and reclaimed water2011

    • Author(s)
      Masaru Ihara, Mariko Ohno, Vimal Kumar, Masanori Narumiya, Seiya Hanamoto, Norihide Nakada, Naoyuki Yamashita, Yasuhiro Kato, Michiko Aoki, Shinichi Miyagawa, Taisen Iguchi, Hiroaki Tanaka
    • Organizer
      GCOE seminar on occurrence and management of emerging contaminants in Japan and UK
    • Place of Presentation
      流域圏総合環境質研究センター(大津市)
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fate of wastewater effluent estrogen/anti-estrogen activities during advanced wastewater treatment2011

    • Author(s)
      Masaru Ihara, Mariko Ohno, Vimal Kumar, Masanori Narumiya, Seiya Hanamoto, Norihide Nakada, Naoyuki Yamashita, Yasuhiro Kato, Michiko Aoki, Shinichi Miyagawa, Taisen Iguchi, Hiroaki Tanaka
    • Organizer
      13th UK-Japan Annual Scientific Workshop of the UK-Japan Partnership
    • Place of Presentation
      ANA Hotel NAGASAKI GLOVERHILL(長崎市)
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Evaluation of estrogenic and anti-estrogenic activity of wastewater by reporter gene assay considering interspecies sensitivity2011

    • Author(s)
      Mariko Ohno, Masaru Ihara, Vimal Kumar, Masanori Narumiya, Seiya Hanamoto, Norihide Nakada, Naoyuki Yamashita, Yasuhiro Kato, Michiko Aoki, Shinichi Miyagawa, Taisen Iguchi, Hiroaki Tanaka
    • Organizer
      13th UK-Japan Annual Scientific Workshop of the UK-Japan Partnership
    • Place of Presentation
      ANA Hotel NAGASAKI GLOVERHILL(長崎市)
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fate of endocrine disrupting chemicals and emerging contaminants in the environment and their remediation2011

    • Author(s)
      Hiroaki TANAKA Kyoto University Mizuhiko MINAMIYAMA
    • Organizer
      13th UK-Japan Annual Scientific Workshop of the UK-Japan Partnership
    • Place of Presentation
      ANA Hotel NAGASAKI GLOVERHILL(長崎市)
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 水循環系における都市排水由来の新規汚染物質問題2011

    • Author(s)
      田中宏明
    • Organizer
      平成23年度水処理生物学会、シンポジウム『水の利用可能性と環境微生物』
    • Place of Presentation
      立命館大学びわこ・くさつキャンパス(草津市)(招待講演)
    • Year and Date
      2011-11-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 種間差を考慮した、下水試料および河川水のエストロゲン様作用の評価2011

    • Author(s)
      大野満理子、井原賢, Vimal Kumar, 花本征也, 成宮正倫, 宮川信一, 井口泰泉, 田中宏明
    • Organizer
      第48回環境工学研究フォーラム
    • Place of Presentation
      大同大学(名古屋市)
    • Year and Date
      2011-11-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Emerging pollution derived from daily life activities in the water environment2011

    • Author(s)
      Hiroaki Tanaka, Takashi Azuma, Ghosh Gopal Chandra, Norihide Nakada, Naoyuki Yamashita
    • Organizer
      Seoul International Symposium on Waterworks 2011
    • Place of Presentation
      大韓商工会議所(韓国)(招待講演)
    • Year and Date
      2011-09-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 使用方法の異なるPPCPsをマーカーとして用いた河川水の生活排水等による汚濁パターンの分類法の開発2011

    • Author(s)
      三浦嘉仁、山城詩織、山中潤二、久保隆、長江真樹、有薗幸司、高尾雄二
    • Organizer
      第20回環境化学討論会
    • Place of Presentation
      熊本県立大学(熊本市)
    • Year and Date
      2011-07-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Evaluation on endocrine disrupting activity and interspecies sensitivies of wastewater samples using the reporter gene assay derived from different organism2011

    • Author(s)
      Mariko Ohno, Masaru Ihara, Vimal Kumar, Masanori Narumiya, Seiya Hanamoto, Shinichi Miyagawa, Taisen Iguchi, Hiroaki Tanaka
    • Organizer
      IWA MICROPOL 2011
    • Place of Presentation
      ニューサウスウェールズ大学(オーストラリア)(招待講演)
    • Year and Date
      2011-07-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Occurrence of Pharmaceuticals and personal care products in aquatic environment around Shenzhen2011

    • Author(s)
      Seiya Hanamoto, Norihide Nakada, Naoyuki Yamashita, Makoto Yasojima, Hiroaki Tanaka
    • Organizer
      GCOE seminar on water and the environment in Asia and U.S.
    • Place of Presentation
      流域圈総合環境質研究センター(大津市)
    • Year and Date
      2011-06-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fate of endocrine disrupting chemicals and emerging contaminants in the environment and their remediation

    • Author(s)
      H. TANAKA, et al.
    • Organizer
      13th UK-Japan Annual Scientific Workshop of the UK-Japan Partnership
    • Place of Presentation
      長崎
    • Related Report
      2013 Final Research Report
  • [Presentation] Water Quality of a Municipal Wastewater Treatment Plant Damaged by Flooding Disaster on the Gyeongan-river, Korea

    • Author(s)
      SangJung Lee, Norihide NAKADA, Ihnsup HAN, Hiroaki TANAKA
    • Organizer
      WET2013
    • Place of Presentation
      東京、東京農工大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] 下水中のエストロゲン様作用と抗エストロゲン作用が互いの測定に与える影響の考察

    • Author(s)
      大野満理子、井原賢、Vimal Kumar、成宮正倫、花本征也、中田典秀、山下尚之、宮川信一、井口泰泉、田中宏明
    • Organizer
      第50回下水道研究発表会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 都市河川における医薬品類の雨天時存在実態の把握

    • Author(s)
      花本征也、中田典秀、山下尚之、田中宏明
    • Organizer
      第50回下水道研究発表会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Photolysis of PPCPs along the river stretch based on the stochastic model, laboratory experiment and the field survey

    • Author(s)
      Hanamoto S, Nakada N, Yamashita N, Tanaka H
    • Organizer
      IWA Micropol & Ecohazard 2013
    • Place of Presentation
      Zurich, Switzerland
    • Related Report
      2013 Annual Research Report
  • [Presentation] Occurrence and Removal of the Free and Conjugated Estrogens in Activated Sludge Processes

    • Author(s)
      V. Kumar, N. Yamashita, N. Nakada, A.C. Johnson, H. Tanaka
    • Organizer
      IWA Micropol & Ecohazard 2013
    • Place of Presentation
      Zurich, Switzerland
    • Related Report
      2013 Annual Research Report
  • [Presentation] 水環境改善に向けた取り組みについて

    • Author(s)
      田中宏明
    • Organizer
      全国建設技術協会第597回建設技術講習会上水道行政の課題・下水道行政の課題
    • Place of Presentation
      新潟市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 生活にからむ水環境汚染の課題と今後の展望

    • Author(s)
      田中宏明
    • Organizer
      京都大学公開講座「リサイクルシステム論-環境と資源の保全に向けた科学・技術・政策」
    • Place of Presentation
      京都、京都大学
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Fate of endocrine disrupting chemicals and emerging contaminants in the environment and their remediation

    • Author(s)
      Hiroaki TANAKA, Seiichiro OKAMOTO, Andrew JOHNSON, Monika JUERGENS
    • Organizer
      15th Annual Scientific Workshop of UK-Japan Co-operation for Research on Endocrine Disrupters in the Aquatic Environment
    • Place of Presentation
      Nagoya
    • Related Report
      2013 Annual Research Report
  • [Presentation] Occurrences and Fates of Emerging Contaminants in the Water Environment and their remediation

    • Author(s)
      Hiroaki TANAKA,Masaru IHARA, Seiichiro OKAMOTO, Andrew JOHNSON, Monika JÜRGENS
    • Organizer
      The 16th annual meeting of JSEDR
    • Place of Presentation
      Hongo Campus (Sanjo Conference Hall) ,THE UNIVERSITY OF TOKYO
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 下水からの水環境水質リスクとその低減化技術の最新動向

    • Author(s)
      田中宏明
    • Organizer
      造水シンポジウム2 0 1 3河川環境を健全に維持するための汚濁物質水質規制の最新動向と各種の造水技術
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Emerging Water Pollution Caused by Pharmaceuticals

    • Author(s)
      Tanaka H
    • Organizer
      2012 Seminar held at Hong Kong University of Science & Technology
    • Place of Presentation
      香港科学技術大学、香港
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 都市生活由来物質の流域水質管理

    • Author(s)
      田中宏明
    • Organizer
      流域水管理研究会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Fate and occurrence of endocrine disrupting chemicals and emerging contaminants in the water environment and STP and their control

    • Author(s)
      Tanaka H
    • Organizer
      14th Annual Scientific Workshop, UK-Japan Co-operation for Research on Endocrine Disrupters in the Aquatic Environment
    • Place of Presentation
      ウインザ、英国
    • Related Report
      2012 Annual Research Report
  • [Presentation] Comparison of the detection sensitivity of anti-androgenic potency of

    • Author(s)
      Nagae M
    • Organizer
      14th Annual Scientific Workshop, UK-Japan Co-operation for Research on Endocrine Disrupters in the Aquatic Environment
    • Place of Presentation
      ウインザ、英国
    • Related Report
      2012 Annual Research Report
  • [Presentation] Approaches for EDCs screening in vitro and for understanding molecular

    • Author(s)
      Miyagawa S
    • Organizer
      14th Annual Scientific Workshop, UK-Japan Co-operation for Research on Endocrine Disrupters in the Aquatic Environment
    • Place of Presentation
      ウインザ、英国
    • Related Report
      2012 Annual Research Report
  • [Presentation] The Basic Consideration for Identification of Anti-estrogenic Chemicals in Wastewater

    • Author(s)
      Ohno M
    • Organizer
      14th Annual Scientific Workshop, UK-Japan Co-operation for Research on Endocrine Disrupters in the Aquatic Environment
    • Place of Presentation
      ウインザ、英国
    • Related Report
      2012 Annual Research Report
  • [Presentation] Emerging pollution of PPCPs and estrogen and seasonal factors in Gyeongan River, South Korea

    • Author(s)
      SangJung Lee
    • Organizer
      4th IWA Young Water Professional Conference 2012
    • Place of Presentation
      ウインザ、英国
    • Related Report
      2012 Annual Research Report
  • [Presentation] Evaluation by Reporter Gene Assay using Estrogen Receptor-α Derived from Multi-species,

    • Author(s)
      Ihara M
    • Organizer
      14th Annual Scientific Workshop, UK-Japan Co-operation for Research on Endocrine Disrupters in the Aquatic Environment
    • Place of Presentation
      ウインザ、英国
    • Related Report
      2012 Annual Research Report
  • [Presentation] 下水試料および下水高度処理水のエストロゲン様作用・抗エストロゲン作用の評価

    • Author(s)
      井原賢
    • Organizer
      第15回環境ホルモン学会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 下水中の抗エストロゲン物質同定のための基礎検討

    • Author(s)
      大野満里子
    • Organizer
      第15回環境ホルモン学会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] Photolysis and toxicity changes of pharmaceuticals during the river transport

    • Author(s)
      Hanamoto S
    • Organizer
      Environmental Health 2013
    • Place of Presentation
      ボストン、米国
    • Related Report
      2012 Annual Research Report
  • [Presentation] Diagnosis of river basins: Concentration of pharmaceuticals and personal care products in river water tell us wastewater burden and treatment level in a river basin.

    • Author(s)
      Nakada N
    • Organizer
      Environmental Health 2013
    • Place of Presentation
      ボストン、米国
    • Related Report
      2012 Annual Research Report
  • [Presentation] 数理モデルと現地調査とに基づく河川流下過程における医薬品類の光分解に関する研究

    • Author(s)
      花本征也
    • Organizer
      第47回水環境学会年会
    • Place of Presentation
      大阪
    • Related Report
      2012 Annual Research Report
  • [Book] エストロゲン様作用,抗エストロゲン作用に関する下水処理の新たな視点からの評価、生物応答を用いた排水評価・管理手法の国内外最新動向2014

    • Author(s)
      田中宏明、井原賢
    • Total Pages
      10
    • Publisher
      NTS
    • Related Report
      2013 Annual Research Report
  • [Remarks] 環境質予見分野

    • URL

      http://www.eqc.kyoto-u.ac.jp/prediction_lab/index.html

    • Related Report
      2012 Annual Research Report
  • [Remarks] 京都大学-清華大学環境技術共同研究・教育センター

    • URL

      http://hse.gcoe.kyoto-u.ac.jp/jp/bases/shenzhen/web/index.html

    • Related Report
      2012 Annual Research Report
  • [Remarks] UK-Japan Joint Research on Endocrine Disrupters

    • URL

      http://www.uk-j.org/index.html

    • Related Report
      2012 Annual Research Report

URL: 

Published: 2011-04-06   Modified: 2021-04-07  

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