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Life-span-development research on the neural base of relaxation effects by a physical exercise

Research Project

Project/Area Number 23300247
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionNihon University

Principal Investigator

SAKATANI Kaoru  日本大学, 工学部, 教授 (90244350)

Co-Investigator(Kenkyū-buntansha) OKAMOTO Masako  東京大学, 大学院・農学生命科学研究科, 特任准教授 (00391201)
小林 寛道  日本大学, 国際関係学部, 教授 (60023628)
辻井 岳雄  日本大学, 医学部, 研究員 (80424216)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Keywordsストレスマネージメント / NIRS / 前頭前野 / 高次脳機能 / 運動 / 補完代替療法 / 予防医学 / 健康科学 / ストレス / prefrontal cortex / stress / working memory / cognitive function / physical exercise / aging / depression / 脳機能 / 近赤外分光法 / 生涯発達研究
Research Abstract

The stress in the modern society is one of the major causes of various diseases. In this study, in order to evaluate stress objectively, we have developed a new system, which employs near-infrared spectroscopy (NIRS), psychological tests and the techniques of evaluating the autonomic nervous system and endocrine system function. Furthermore, using this system, we evaluated the relaxation effect of the physical exercise in middle and old aged people, and revealed that even mild exercise had a relaxation effect. In addition, such mild exercise improved working memory performance associated with an increase of the prefrontal cortex activity to working memory tasks. We suggest that combination of the present stress monitoring system and physical exercise may prevent various stress-induced diseases.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (62 results)

All 2014 2013 2012 2011 Other

All Journal Article (26 results) (of which Peer Reviewed: 13 results) Presentation (30 results) (of which Invited: 5 results) Book (3 results) Remarks (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Bayesian Prediction of Anxiety Level in Aged People at Rest Using 2-Channel NIRS Data from Prefrontal Cortex2014

    • Author(s)
      Fukuda Y, Ishikawa W, Kanayama R, Matsumoto T, Takemura N, Sakatani K
    • Journal Title

      Adv Exp Med Biol

      Volume: 812 Pages: 303-308

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] Ginkobiloba extract improves working memory performance in middle-aged women : role of asymmetry of prefrontal cortex activity during a working memory task2014

    • Author(s)
      Sakatani K, Tanida M, Hirao N, Takemura N
    • Journal Title

      Adv Exp Med Biol

      Volume: 812 Pages: 295-301

    • Related Report
      2013 Final Research Report
  • [Journal Article] Asymmetrical changes in cerebral blood oxygenation induced by an active standing test in children with postural tachycardia syndrome2014

    • Author(s)
      Kamiyama Y, Fujita Y, Fuchigami T, Kamiyama H, Takahashi S, Sakatani K
    • Journal Title

      Adv Exp Med Biol

      Volume: 812 Pages: 271-278

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] Physiological Mechanism of Increase in Deoxy-hemoglobin Concentration During Neuronal Activation in Patients with Cerebral Ischemia : A Simulation Study with the Balloon Model2014

    • Author(s)
      Takemura N, Sakatani K, Yoshino A, Hirayama T, Katayama Y
    • Journal Title

      Adv Exp Med Biol

      Volume: 812 Pages: 225-231

    • Related Report
      2013 Final Research Report
  • [Journal Article] Correlation between asymmetry of spontaneous oscillation of hemodynamic changes in the prefrontal cortex and anxiety levels : a near-infrared spectroscopy study2014

    • Author(s)
      Ishikawa W, Sato M, Fukuda Y, Matsumoto T, Takemura N, Sakatani K
    • Journal Title

      J Biomed Opt

      Volume: 19(2) Pages: 27005-27005

    • Related Report
      2013 Final Research Report
  • [Journal Article] Ginkobiloba extract improves working memory performance in middle-aged women: role of asymmetry of prefrontal cortex activity during a working memory task2014

    • Author(s)
      Kaoru Sakatani
    • Journal Title

      Adv Exp Med Biol

      Volume: 812 Pages: 295-301

    • DOI

      10.1007/978-1-4939-0620-8_39

    • ISBN
      9781493905836, 9781493906208
    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanism of Increase in Deoxy-hemoglobin Concentration During Neuronal Activation in Patients with Cerebral Ischemia: A Simulation Study with the Balloon Model2014

    • Author(s)
      Takemura N, Sakatani K, Yoshino A, Hirayama T, Katayama Y.
    • Journal Title

      Adv Exp Med Biol

      Volume: 812 Pages: 225-231

    • DOI

      10.1007/978-1-4939-0620-8_30

    • ISBN
      9781493905836, 9781493906208
    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Correlation between asymmetry of spontaneous oscillation of hemodynamic changes in the prefrontal cortex and anxiety levels: a near-infrared spectroscopy study2014

    • Author(s)
      Kaoru Sakatani
    • Journal Title

      J Biomed Opt

      Volume: 19(2) Issue: 2 Pages: 27005-27005

    • DOI

      10.1117/1.jbo.19.2.027005

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of experimentally deviated mandibular position on stress response2013

    • Author(s)
      Amemiya A, Takeda T, Nakajima K, Ishigami K, Tsujii T, Sakatani K
    • Journal Title

      Adv Exp Med Biol

      Volume: 765 Pages: 1-7

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
  • [Journal Article] New method of analyzing NIRS data from prefrontal cortex at rest2013

    • Author(s)
      Ishikawa W, Sato M, Fukuda Y, Matsumoto T, Takemura N, Tsujii T, Sakatani K
    • Journal Title

      Adv Exp Med Biol

      Volume: 789 Pages: 391-397

    • Related Report
      2013 Final Research Report
  • [Journal Article] NIRS-based neurofeedback learning systems for controlling activity of the prefrontal cortex2013

    • Author(s)
      Sakatani K, Takemoto N, Tsujii T, Yanagisawa K, Tsunashima H
    • Journal Title

      Adv Exp Med Biol

      Volume: 789 Pages: 449-454

    • Related Report
      2013 Final Research Report
  • [Journal Article] Acute effects of physical exercise on prefrontal cortex activity in older adults : a functional near-infrared spectroscopy study2013

    • Author(s)
      Tsujii T, Komatsu K, Sakatani K
    • Journal Title

      Adv Exp Med Biol

      Volume: 765 Pages: 293-298

    • Related Report
      2013 Final Research Report
  • [Journal Article] Bayesian STAI anxiety index predictions based on prefrontal cortex NIRS data for the resting state2013

    • Author(s)
      Sato M, Ishikawa W, Suzuki T, Matsumoto T, Tsujii T, Sakatani K
    • Journal Title

      Adv Exp Med Biol

      Volume: 765 Pages: 251-256

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
  • [Journal Article] Effects of occlusal disharmony on working memory performance and prefrontal cortex activity induced by working memory tasks measured by NIRS2013

    • Author(s)
      Sakatani K, Tsujii T, Hirayama T, Katayama Y, Takeda T, Amemiya A, IshigamiK
    • Journal Title

      Adv Exp Med Biol

      Volume: 765 Pages: 239-244

    • Related Report
      2013 Final Research Report
  • [Journal Article] 中高年女性の抑うつに対する運動のリラクセーション効果2013

    • Author(s)
      小松一俊 、辻井岳雄、酒谷薫
    • Journal Title

      自律神経

      Volume: 50 Pages: 219-223

    • NAID

      10031201791

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of occlusal disharmony on working memory performance and prefrontal2013

    • Author(s)
      Sakatani K
    • Journal Title

      Adv Exp Med Biol.

      Volume: 765 Pages: 239-244

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute effects of physical exercise onprefrontal cortex activity in older adults: a functional near-infrared spectroscopy study2013

    • Author(s)
      Tsujii T
    • Journal Title

      Adv Exp Med Biol

      Volume: 765 Pages: 293-298

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optical diagnosis of mental stress2012

    • Author(s)
      Sakatani K
    • Journal Title

      Adv Exp Med Biol

      Volume: 737(review) Pages: 89-95

    • Related Report
      2013 Final Research Report
  • [Journal Article] Relation between working memory performance and evoked cerebral blood oxygenation changes in the prefrontal cortex evaluated by quantitative time-resolved near-infrared spectroscopy2012

    • Author(s)
      Tanida M, Sakatani K, Tsujii T
    • Journal Title

      Neurol Res

      Volume: 34(2) Pages: 114-119

    • Related Report
      2013 Final Research Report
  • [Journal Article] Optical diagnosis of mental stress: review2012

    • Author(s)
      Sakatani K
    • Journal Title

      Adv Exp Med Biol.

      Volume: 737 Pages: 89-95

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relation between working memory performanceand evoked cerebral blood oxygenation changes in the prefrontal cortex evaluated by quantitative time-resolved near-infrared spectroscopy2012

    • Author(s)
      Tanida M
    • Journal Title

      Neurol Res

      Volume: 34 Pages: 114-119

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relation between working memory performance and evoked cerebral blood oxygenation changes in the prefrontal cortex evaluated by quantitative time-resolved near infrared spectroscopy2012

    • Author(s)
      Tanida M., Sakatani K, Tsujii T.
    • Journal Title

      Neurological Research

      Volume: 34 Pages: 114-119

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optical diagnosis of mental stress : review2012

    • Author(s)
      Sakatani K
    • Journal Title

      Adv Exp Med Biol

      Volume: 737 Pages: 89-95

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluating the roles of the inferior frontal gyrus and superior parietal lobule in deductive reasoning : an rTMS study2011

    • Author(s)
      Tsujii T, Sakatani K, Masuda S, Akiyama T, Watanabe S
    • Journal Title

      Neuroimage

      Volume: 15 Pages: 640-646

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Progress in NIRS monitoring of cerebral blood flow2011

    • Author(s)
      Sakatani K, Yokose N, Katagiri A, Hoshino T, Fujiwara N, Murata Y, Hirayamama T, Katayama Y
    • Journal Title

      Brain Nerve

      Volume: 63 Pages: 955-961

    • NAID

      40018968217

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of the acute effects of alcohol on asymmetry of inferior frontal cortex activity during a Go/No-Go task using functional near-infrared spectroscopy2011

    • Author(s)
      Tsujii T, Sakatani K, Nakashima E, Igarashi T, Katayama Y
    • Journal Title

      Psychopharmacology (Berl)

      Volume: 217 Pages: 595-603

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 脳神経外科領域における光学的計測法の応用2013

    • Author(s)
      酒谷 薫
    • Organizer
      STR Medical Conference
    • Place of Presentation
      郡山
    • Year and Date
      2013-12-20
    • Related Report
      2013 Final Research Report
  • [Presentation] 近赤外分光法(NIRS)を用いたストレス評価法2013

    • Author(s)
      酒谷 薫
    • Organizer
      第16回福島神経疾患治療研究会
    • Place of Presentation
      郡山
    • Year and Date
      2013-12-14
    • Related Report
      2013 Final Research Report
  • [Presentation] 光学的脳機能計測法による脳と心の健康状態(ストレス, 認知機能)の評価法2013

    • Author(s)
      酒谷 薫
    • Organizer
      第8回日本大学先端バイオフォーラム
    • Place of Presentation
      東京
    • Year and Date
      2013-11-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 脳虚血患者の神経活動における脱酸素化ヘモグロビン増加の生理メカニズム2013

    • Author(s)
      酒谷 薫, 他
    • Organizer
      第20回医用近赤外線分光法研究会
    • Place of Presentation
      東京
    • Year and Date
      2013-10-12
    • Related Report
      2013 Final Research Report
  • [Presentation] NIRSの予防医学への応用-NIRSによる脳と心の健康評価-2013

    • Author(s)
      酒谷 薫
    • Organizer
      第14回早期認知症学会
    • Place of Presentation
      浜松
    • Year and Date
      2013-09-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 高齢社会を豊かにする脳と心の健康増進支援システム2013

    • Author(s)
      酒谷 薫
    • Organizer
      神戸市北区医師会創立40周年記念講演会
    • Place of Presentation
      神戸
    • Year and Date
      2013-08-31
    • Related Report
      2013 Final Research Report
  • [Presentation] Monitoring of Brain Function by Near Infrared Spectroscopy for Prevention of Brain Diseases2013

    • Author(s)
      Sakatani K. et al
    • Organizer
      The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'13)
    • Place of Presentation
      大阪
    • Year and Date
      2013-07-03
    • Related Report
      2013 Final Research Report
  • [Presentation] 未来型脳機能診断システムと未病治療2013

    • Author(s)
      酒谷 薫
    • Organizer
      2013年度ICTスマート医療
    • Place of Presentation
      東京
    • Year and Date
      2013-06-15
    • Related Report
      2013 Final Research Report
  • [Presentation] 現代科学から見た中国伝統医学の基礎理論2013

    • Author(s)
      酒谷 薫
    • Organizer
      日本医工学治療学会第29回学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2013-04-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 福島県の医療福祉産業は今, 何をやるべきか?被災者のストレス問題2012

    • Author(s)
      酒谷 薫
    • Organizer
      第2回医療福祉機器事業創出研究会
    • Place of Presentation
      郡山
    • Year and Date
      2012-12-20
    • Related Report
      2013 Final Research Report
  • [Presentation] 香り刺激によるストレス反応の変化 : NIRS による検討2012

    • Author(s)
      酒谷 薫
    • Organizer
      第42回日本臨床神経生理学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-11-09
    • Related Report
      2013 Final Research Report
  • [Presentation] 時間分解スペクトロスコピーによる脳虚血の検出2012

    • Author(s)
      酒谷 薫
    • Organizer
      第42回日本臨床神経生理学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-11-08
    • Related Report
      2013 Final Research Report
  • [Presentation] NIRSの予防医学への応用-NIRSによる脳と心の健康評価-2012

    • Author(s)
      酒谷 薫
    • Organizer
      第19回医用近赤外分光法研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-10-13
    • Related Report
      2013 Final Research Report
  • [Presentation] NIRSを用いた脳機能に対する薬物効果の評価法2012

    • Author(s)
      酒谷 薫
    • Organizer
      第15回日本薬物脳波学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2012-06-09
    • Related Report
      2013 Final Research Report
  • [Presentation] NIRSによる認知機能の定量的評価法の開発2012

    • Author(s)
      酒谷 薫
    • Organizer
      第51回日本生体医工学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-05-10
    • Related Report
      2013 Final Research Report
  • [Presentation] 脳腫瘍, 脳血管障害における脳機能イメージングのピットフォール2012

    • Author(s)
      酒谷 薫
    • Organizer
      Fujita Neuroscience Seminar
    • Place of Presentation
      名古屋
    • Year and Date
      2012-01-27
    • Related Report
      2013 Final Research Report
  • [Presentation] NIRSを用いた薬物効果の判定2012

    • Author(s)
      酒谷 薫
    • Organizer
      第15回日本薬物脳波学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] NIRSの予防医学への応用-NIRSによる脳と心の健康評価-2012

    • Author(s)
      酒谷 薫
    • Organizer
      第20回医用近赤外線分光法研究会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 香り刺激によるストレス反応の変化:NIRS による検討2012

    • Author(s)
      酒谷 薫
    • Organizer
      第42回日本臨床神経生理学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] NIRS-based neurofeedback learning systems for controlling activity of the prefrontal cortex2012

    • Author(s)
      Sakatani K
    • Organizer
      ISOTT 2012
    • Place of Presentation
      Bruges, Belgium
    • Related Report
      2012 Annual Research Report
  • [Presentation] New method of analysing NIRS data from prefrontal cortex at rest2012

    • Author(s)
      Ishikawa W
    • Organizer
      ISOTT 2012
    • Place of Presentation
      Bruges, Belgium
    • Related Report
      2012 Annual Research Report
  • [Presentation] Monitoring of hemodynamic change in patients with carotid artery stenosis during the tilt test using a wearable near- infrared spectroscopy2012

    • Author(s)
      Igarashi T
    • Organizer
      ISOTT 2012
    • Place of Presentation
      Bruges, Belgium
    • Related Report
      2012 Annual Research Report
  • [Presentation] Near infrared spectroscopy (NIRS) may be prognostication of neurological outcome in cardiac arrest patients2012

    • Author(s)
      Yagi T
    • Organizer
      ISOTT 2012
    • Place of Presentation
      Bruges, Belgium
    • Related Report
      2012 Annual Research Report
  • [Presentation] NIRSによる認知機能の定量的評価法の開発2012

    • Author(s)
      酒谷 薫
    • Organizer
      第19回日本生体医工学会・BME on Dementia研究会
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 前頭前野の安静時脳血流酸素代謝の 左右非対称性による不安心理状態の推定法2012

    • Author(s)
      石川わかな
    • Organizer
      第16回酸素ダイナミックス研究会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 抑うつの治療を目的としたニューロフィードバックシステムの開発2012

    • Author(s)
      柳沢一機
    • Organizer
      第14回日本ヒト脳機能マッピング学会
    • Place of Presentation
      札幌
    • Related Report
      2012 Annual Research Report
  • [Presentation] 福島県の医療福祉産業は、今、何をやるべきか「被災者のストレス問題」2012

    • Author(s)
      酒谷 薫
    • Organizer
      第2回医療福祉機器事業創出研究会
    • Place of Presentation
      郡山
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] NIRSの予防医学への応用2011

    • Author(s)
      酒谷薫
    • Organizer
      日本光学会(応用物理学会)生体医用光学研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-12-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] NIRSの健康科学への応用2011

    • Author(s)
      酒谷薫
    • Organizer
      NUBRAIN
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-11-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒト頭部の光路長およびヘモグロビン濃度のマッピング2011

    • Author(s)
      片桐彰久、岡本雅子、横瀬憲明、五十嵐崇浩、星野達哉、藤原徳生、村田佳宏、酒谷薫、片山容一、壇一平太
    • Organizer
      ヒト脳機能マッピング学会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-01
    • Related Report
      2011 Annual Research Report
  • [Book] NIRS-基礎と臨床-2012

    • Author(s)
      監修 : 酒谷 薫 編集 : 岡田英史 星 詳子 宮井一郎 渡辺英寿
    • Publisher
      新興医学出版社
    • Related Report
      2013 Final Research Report
  • [Book] NIRS-基礎と臨床-2012

    • Author(s)
      酒谷薫(監修、編著)
    • Total Pages
      277
    • Publisher
      新興医学出版社
    • Related Report
      2011 Annual Research Report
  • [Book] 東洋医学が教える脳の「養生法」2011

    • Author(s)
      酒谷薫
    • Total Pages
      255
    • Publisher
      実業之日本社
    • Related Report
      2011 Annual Research Report
  • [Remarks] 酒谷研究室

    • URL

      http://sakatani-lab.org/

    • Related Report
      2013 Final Research Report
  • [Remarks] 次世代工学技術研究センター

    • URL

      http://www.ce.nihon-u.ac.jp/ResearchCenter/newcat/newcat.html

    • Related Report
      2013 Final Research Report
  • [Patent(Industrial Property Rights)] 脳活動状態解析装置2011

    • Inventor(s)
      綱島均、酒谷薫、深井英幸、柳沢一機
    • Industrial Property Rights Holder
      日本大学
    • Industrial Property Number
      2011-193886
    • Filing Date
      2011-09-06
    • Related Report
      2011 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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