| Budget Amount *help |
¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000)
Fiscal Year 2013: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2012: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2011: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Research Abstract |
Membrane protein is an important target for drug discovery. In this study, using solid state NMR, we have developed a method to detect a signal from a target membrane protein expressed on the cell surface. Special isotope labeling technique enabled to suppress the background signals and enhanced the signal-to-noise ratio. Finally we succeeded to detect NMR signals of the target membrane protein using live cells.
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