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The advanced study of the role of detoxification treatment of inorganic arsenic for the prevention of health disorders of arsenic and chronic arsenic poisoning

Research Project

Project/Area Number 23406003
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Environmental technology/Environmental materials
Research InstitutionKitasato University

Principal Investigator

YAMAUCHI Hiroshi  北里大学, 医療衛生学部, 教授 (90081661)

Co-Investigator(Kenkyū-buntansha) YOSHIDA Takahiko  旭川医科大学, 医学部, 教授 (90200998)
高田 礼子  聖マリアンナ医科大学, 医学部, 教授 (30321897)
Co-Investigator(Renkei-kenkyūsha) TAKATA Ayako  聖マリアンナ医科大学, 医学部, 教授 (30321897)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2013: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Keywords慢性ヒ素中毒 / ヒ素 / 無毒化 / 無毒化ヒ素 / アルセノベタイン / 飲料水 / 汚染土壌 / 無毒化処理 / ヒ素化学兵器 / ジメチルアルシン酸 / 安全性試験 / 二酸化チタン / 触媒サイクル / ヒ素汚染
Research Abstract

Chronic arsenic poisoning, currently, inorganic arsenic (iAs) contamination of drinking water causes the victim of more than 50 million has been identified in Asia. We have developed a synthesis technology simple to detoxification process the iAs is a causative agent of arsenic poisoning. Establishing the non-toxicity of arsenobetaine (AsB) on scientific and legal grounds will expedite the application of arsenic detoxification in many areas as a safe and eco-friendly way to treat iAs in the natural environment. The presence of titanium oxide photocatalyst, acetic acid, by light irradiation, the iAs is converted to AsB. Examination of the behavior in seawater of AsB as ocean dumping model, was present in a stable manner to reach the (2ppb) arsenic concentration originally present in seawater within 24 hours. It was able to ocean dumping of toxic arsenic and establishment of low- cost process of ultimate propose a possible conditions.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (19 results)

All 2013 2012 2011 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (14 results) (of which Invited: 4 results)

  • [Journal Article] ヒトにおけるブロッコリー摂取後のヒ素化合物の代謝と排泄について2013

    • Author(s)
      水津珠世、井上葉子、伊与亨、吉田貴彦、伊藤俊宏、中木良彦、長谷川理恵、塙由布子、山内博
    • Journal Title

      臨床環境医学

      Volume: 22 Pages: 59-65

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rare metal recycling and arsenic detoxification by TiO_2 photocatalyst2012

    • Author(s)
      Nakamura K., Yamauchi H
    • Journal Title

      Abstracts of 92nd Annual Meeting of the Chemical Society of Japan

      Volume: Vol.I, 3PD-041 Pages: 88-89

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Arsenic detoxification by TiO_2 photocatalyst2012

    • Author(s)
      Nakamura K., Yamauchi H
    • Journal Title

      Abstracts of 92nd Annual Meeting of the Chemical Society of Japan

      Volume: Vol.II, 3G1-29 Pages: 507-507

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 提言, 老朽・遺棄化学兵器の廃棄処理の実施における保安対策 : 中国の遺棄化学兵器処理の開始に当たって2011

    • Author(s)
      山内博
    • Journal Title

      日本学術会議

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Arsenic detoxification2011

    • Author(s)
      Yamauchi H., Nakamura K
    • Journal Title

      Abstracts of the 16th Arsenic Symposium

      Pages: 60-61

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] ヒ素中毒やヒ素汚染の検証に対するヒ素の同一性の検証2013

    • Author(s)
      山内博
    • Organizer
      日本学術会議
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 化学兵器廃棄と安全性 : ヒ素による被ばくの現状と防止対策2013

    • Author(s)
      山内博
    • Organizer
      日本学術会議安全工学シンポジウ
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] Detoxifying inorganic arsenic for benefit of human health and the enviroment2013

    • Author(s)
      Hiroshi Yamauchi
    • Organizer
      44th World Chemistry Congress
    • Place of Presentation
      Istanbul, Turkey, Congress Secretariat
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] ヒ素による被ばくの現状と防止対策2013

    • Author(s)
      山内博
    • Organizer
      日本学術会議安全工学シンポジウム
    • Place of Presentation
      日本学術会議講堂、乃木坂
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 酸化チタン光触媒を用いた無機ヒ素の無毒化処理技術の開発2012

    • Author(s)
      中村浩一郎、山内博
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶応義塾大学日吉キャンパス(横浜市)
    • Year and Date
      2012-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 酸化チタン光触媒を用いたヒ素の無毒化とレアメタルのリサイクル技術の開発2012

    • Author(s)
      中村浩一郎、山内博
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶応義塾大学日吉キャンパス(横浜市)
    • Year and Date
      2012-03-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] 無機ヒ素の無毒化処理に関する背景と展望2012

    • Author(s)
      山内博
    • Organizer
      日本水処理生物学会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 酸化チタン光触媒を用いた無機ヒ素の無毒化処理技術の開発2012

    • Author(s)
      中村浩一郎, 山内博
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] 酸化チタン光触媒を用いたヒ素の無毒化とレアメタルのリサイクル技術の開発2012

    • Author(s)
      中村浩一郎, 山内博
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] 無機ヒ素の無毒化処理技術2011

    • Author(s)
      山内博
    • Organizer
      資源素材学会2011
    • Place of Presentation
      大阪府立大学中百舌鳥キャンパス(大阪府堺市)(招待講演)
    • Year and Date
      2011-09-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 無機ヒ素の無毒化処理技術2011

    • Author(s)
      山内博
    • Organizer
      資源材料学会
    • Place of Presentation
      堺
    • Related Report
      2013 Final Research Report
  • [Presentation] 無機ヒ素の無毒化処理合成アルセノベタインの細胞毒性評価2011

    • Author(s)
      山内博, 中野瑞穂, 井上葉子, 中村浩一郎等
    • Organizer
      第81回日本衛生学会学術総会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 化学兵器廃棄事業の安全を目指して:ヒ素による被ばくの現状と防止対策

    • Author(s)
      山内博
    • Organizer
      日本学術会議安全工学シンポジウム2013
    • Place of Presentation
      日本学術会議本部講堂 東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 無機砒素の無毒化処理に関する背景と展望

    • Author(s)
      山内博
    • Organizer
      日本水処理生物学会
    • Place of Presentation
      東京都、北里大学白金コンベンションホール
    • Related Report
      2012 Annual Research Report
    • Invited

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Published: 2011-04-06   Modified: 2019-07-29  

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