• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Computer-aided diagnosis of lung cancers based on quantitative analysis of time-interval changes on thoracic CT images

Research Project

Project/Area Number 23500518
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionThe University of Tokushima

Principal Investigator

KAWATA Yoshiki  徳島大学, ソシオテクノサイエンス研究部, 准教授 (70274264)

Co-Investigator(Kenkyū-buntansha) NIKI Noboru  徳島大学, 大学院・ソシオテクノサイエンス研究部, 教授 (80116847)
OHMATSU Hironobu  国立がん研究センター, 東病院, 副科長 (40415518)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords肺がん / CT画像 / CT値ヒストグラム / 経過観察支援 / 経過支援観察 / 予後予測 / 拡大CT / 経時変化 / 4次元CT
Research Abstract

Lung cancer is the most common cause of cancer death worldwide. CT is the modality of choice for lung imaging because this modality is the most sensitive way for imaging lung in vivo currently. Some evidences suggested that CT with a low-dose imaging protocol may improve pulmonary nodule sensitivity relative to radiography. While this study does show the efficacy of CT based screening, physicians often face the problem of deciding an appropriate management strategies for maximizing patient survival and preserving lung function. This study focuses on a framework within which CT value histograms is used to represent internal structures of pulmonary nodules, aiming at classifying patients between those at high risk of disease progression (high-risk group) and those at low risk of disease progression (low-risk group).

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (28 results)

All 2014 2013 2012

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (15 results) (of which Invited: 3 results) Book (4 results)

  • [Journal Article] 胸部マルチスライス CT 画像における葉間裂抽出法2013

    • Author(s)
      松廣幹雄, 鈴木秀宣, 河田佳樹, 仁木登, 上野淳二, 中野恭幸, 小川惠美子, 室繁郎, 大松広伸, 森山紀之
    • Journal Title

      電子情報通信学会論文誌

      Volume: Vol.J.96-D, No.4 Pages: 834-843

    • NAID

      110009596331

    • URL

      http://ci.nii.ac.jp/naid/110009596331

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 胸部マルチスライスCT画像における葉間裂抽出法2013

    • Author(s)
      松廣幹雄,鈴木秀宣,河田佳樹,仁木登,上野淳二,中野恭幸,小川惠美子,室繁郎,大松広伸,森山紀之
    • Journal Title

      電子情報通信学会論文誌

      Volume: J.96-D Pages: 834-843

    • NAID

      110009596331

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 胸部マルチスライスCT 画像を用いた骨粗鬆症診断支援システム2013

    • Author(s)
      高橋英治
    • Journal Title

      電子情報通信学会論文誌

      Volume: Vol.J.96-D,No.4 Pages: 892-900

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 胸部マルチスライスCT画像における葉間裂抽出法2013

    • Author(s)
      松廣幹雄
    • Journal Title

      電子情報通信学会論文誌

      Volume: Vol.J.96-D,No.4 Pages: 834-843

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] A method for determining the modulation transfer function from thick microwire profiles measured with x-ray microcomputed tomography2012

    • Author(s)
      Y.Nakaya, Y.Kawata, N.Niki, K.Umetani, H.Ohmatsu, N.Moriyama
    • Journal Title

      Medical Physics

      Volume: Vol.39, No.7 Issue: 7Part1 Pages: 4347-4364

    • DOI

      10.1118/1.4729711

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Quantitative classification based on CT histogram analysis of non-small cell lung cancer: Correlation with histopathological characteristics and recurrence-free survival2012

    • Author(s)
      Y.Kawata, N.Niki, H.Ohmatsu, M.Kusumoto, T.Tsuchida, K.Eguchi, M.Kaneko, N.Moriyama
    • Journal Title

      Medical Physics

      Volume: Vol.39, No.2 Issue: 2 Pages: 988-1000

    • DOI

      10.1118/1.3679017

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative classification based on CT histogram analysis of non-small cell lung cancer: Correlations with histopathological characteristics and recurrence-free survival2012

    • Author(s)
      Yoshiki Kawata
    • Journal Title

      Medical Physics

      Volume: Vol.39, No.2 Pages: 988-1000

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Image-based computer-aided prognosis of lung cancer: Predicting patient recurrent-free survival via a variational Bayesian mixture modeling framework for cluster analysis of CT histograms2012

    • Author(s)
      Yoshiki Kawata
    • Journal Title

      Proc. SPIE Medical Imaging

      Volume: Vol.8315

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] A method for modulation transfer function determination from blood vessel profiles measured in computed tomography2012

    • Author(s)
      Yoshihiro Nakaya
    • Journal Title

      Proc. SPIE Medical Imaging

      Volume: Vol.8313

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Potential usefulness of a topic model-based categorization of lung cancers as quantitative CT biomarkers for predicting the recurrence risk after curative resection2014

    • Author(s)
      Y.Kawata, N.Niki, H.Ohmtsu, et al
    • Organizer
      Proc. SPIE Medical Imaging
    • Place of Presentation
      Town & Country Resort and Convention Center (San Diego, California, United States )
    • Related Report
      2013 Final Research Report
  • [Presentation] Potential usefulness of a topic model-based categorization of lung cancers as quantitative CT biomarkers for predicting the recurrence risk after curative resection2014

    • Author(s)
      Y.Kawata, N.Niki, H.Ohmatsu, K.Aokage, M.Satake, M.Kusumoto, T.Tsuchida, K.Eguchi, M.Kaneko, N.Moriyama
    • Organizer
      Proc. SPIE Medical Imaging
    • Place of Presentation
      Town & Country Resort and Convention Center(San Diego, California, United States )
    • Related Report
      2013 Annual Research Report
  • [Presentation] Stochastic tracking of small pulmonary vessels in human lung alveolar walls using synchrotron radiation micro CT images2013

    • Author(s)
      Y.Kawata, N.Niki, et al
    • Organizer
      Proc. SPIE Medical Imaging
    • Place of Presentation
      Disney Coronado Springs resort 国際会議場 (Lake Buena Vista, Florida USA)
    • Related Report
      2013 Final Research Report
  • [Presentation] Tracking time interval changes of pulmonary nodules on follow-up 3D CT images via image-based risk score of lung cancer2013

    • Author(s)
      Y.Kawata, N.Niki, H.Ohmatsu, et al
    • Organizer
      Proc. SPIE Medical Imaging
    • Place of Presentation
      Disney Coronado Springs resort 国 際 会 議 場 (Lake Buena Vista, Florida USA)
    • Related Report
      2013 Final Research Report
  • [Presentation] Tracking time interval changes of pulmonary nodules on follow-up 3D CT images via image-based risk score of lung cancer2013

    • Author(s)
      Yoshiki Kawata
    • Organizer
      Proc. SPIE Medical Imaging
    • Place of Presentation
      Florida Orland (Disney Coronado Springs Resort)
    • Related Report
      2012 Research-status Report
  • [Presentation] Stochastic tracking of small pulmonary vessels in human lung alveolar walls using synchrotron radiation micro CT images2013

    • Author(s)
      Yoshiki Kawata
    • Organizer
      Proc. SPIE Medical Imaging
    • Place of Presentation
      Florida Orland (Disney Coronado Springs Resort)
    • Related Report
      2012 Research-status Report
  • [Presentation] 【大会長講演】肺のCT画像解析2013

    • Author(s)
      仁木登
    • Organizer
      第5回呼吸機能イメージング研究会学術集会
    • Place of Presentation
      徳島大学(徳島県)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 拡大CT画像を用いた経時変化の解析に基づく肺がんのコンピュータ支援予後予測2013

    • Author(s)
      河田佳樹
    • Organizer
      第8回京滋呼吸器リサーチフォーラム
    • Place of Presentation
      京都リサーチパーク(京都府)
    • Related Report
      2012 Research-status Report
  • [Presentation] 胸部 3 次元 CT画像を用いた肺がんの鑑別診断支援2012

    • Author(s)
      河田佳樹
    • Organizer
      電子情報通信学会技術研究報告医用画像
    • Place of Presentation
      ぶんかテンブス館(沖縄県那覇市)
    • Year and Date
      2012-01-19
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Image-based computer-aided prognosis of lung cancer : Predicting patient recurrent-free survival via a variational Bayesian mixture modeling framework for cluster analysis of CT histograms2012

    • Author(s)
      Y.Kawata, N.Niki, H.Ohmtsu, et al
    • Organizer
      Proc. SPIE Medical Imaging
    • Place of Presentation
      Town & Country Resort and Convention Center (San Diego, California, United States )
    • Related Report
      2013 Final Research Report
  • [Presentation] A method for modulation transfer function determination from blood vessel profiles measured in computed tomography2012

    • Author(s)
      Y.Nakaya, Y.Kawata, N.Niki, et al
    • Organizer
      Proc. SPIE Medical Imaging
    • Place of Presentation
      Town & Country Resort and Convention Center (San Diego, California, United States )
    • Related Report
      2013 Final Research Report
  • [Presentation] 【教育講演】肺の画像解析-CADeとCADx2012

    • Author(s)
      仁木登
    • Organizer
      第21回日本コンピュータ外科学会大会
    • Place of Presentation
      あわぎんホール(徳島県)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 肺がん・COPD・骨粗鬆症のCT画像解析2012

    • Author(s)
      仁木 登
    • Organizer
      第4回呼吸機能イメージング研究会学術集会(招待講演)
    • Place of Presentation
      ピアザ淡海(滋賀県)
    • Related Report
      2011 Research-status Report
  • [Presentation] 胸部3次元CT画像を用いた肺がんの鑑別診断支援2012

    • Author(s)
      河田 佳樹
    • Organizer
      電子情報通信学会技術研究報告医用画像(招待講演)
    • Place of Presentation
      那覇市ぶんかテンブス館(沖縄県)
    • Related Report
      2011 Research-status Report
  • [Presentation] Computer aided diagnosis for chest CT images2012

    • Author(s)
      Noboru Niki
    • Organizer
      The 2012 International Workshop on Advanced Image Technology(招待講演)
    • Place of Presentation
      Hotel Majestic Saigon (Ho Chi Minh City, Vietnam)
    • Related Report
      2011 Research-status Report
  • [Book] 第6章コンピュータ支援検出/診断 2 CT 画像, 実践医用画像解析ハンドブック2012

    • Author(s)
      仁木登, 河田佳樹, 鈴木秀宣
    • Total Pages
      835
    • Publisher
      株式会社オーム社
    • Related Report
      2013 Final Research Report
  • [Book] II. 画像処理と解析 2.X 線 CT 画像 2.3 肺, 医用画像ハンドブック2012

    • Author(s)
      仁木登, 河田佳樹, 鈴木秀宣
    • Total Pages
      777
    • Publisher
      日本医用画像工学会
    • Related Report
      2013 Final Research Report
  • [Book] 実践医用画像解析ハンドブック(分担 第6章コンピュータ支援検出/診断)2012

    • Author(s)
      仁木登
    • Total Pages
      10
    • Publisher
      株式会社オーム社
    • Related Report
      2012 Research-status Report
  • [Book] 医用画像ハンドブック(分担 II.画像処理と解析 2.X線CT画像 2.3肺)2012

    • Author(s)
      仁木登
    • Total Pages
      7
    • Publisher
      日本医用画像工学会
    • Related Report
      2012 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi