Development of methodology to quantify electron transfer between single molecules
| Project/Area Number |
23550103
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
NISHINO Tomoaki 大阪府立大学, 工学(系)研究科(研究院), 准教授 (80372415)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 走査型トンネル顕微鏡 / 分子探針 / 相互作用 / 電子移動 / 分子エレクトロニクス / DNA / バイオセンサ |
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| Research Abstract |
In the present research project, we developed the first methodology by using molecular tip of scanning tunneling microscopy to quantify electron transfer taking place between a single molecule and adjacent another single molecule. This methodology allowed us to, for example, reveal that a hydrogen bond conducts electrons better than a covalent bond at short range. Moreover, we systematically investigated the electron transfer between single molecules mediated by a variety of chemical interactions. These studies provided novel insights and phenomena mandatory for the future realization of molecular electronics.
In addition, we demonstrated that single-molecule detection of DNA can be achieved based on the methodology for the measurement of the electron transfer between single molecules. Single-stranded DNA was utilized as a probe tip, and hybridization of this DNA tip and target DNA induce electron tunneling through the resulting DNA duplex.
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Report
(4 results)
Research Products
(85 results)
