Functional analysis of insect excretion through aquaporin water channel in insects
Project/Area Number |
23580071
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Applied entomology
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Research Institution | Tottori University |
Principal Investigator |
AZUMA Masaaki 鳥取大学, (連合)農学研究科(研究院), 教授 (20175871)
|
Co-Investigator(Kenkyū-buntansha) |
OBAYASHI Jun 神戸大学, 大学院理学研究科, GCOEリサー チアソシエイト (70242930)
|
Co-Investigator(Renkei-kenkyūsha) |
ISHIDA Yuko (90509861)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
Keywords | 浸透圧調節 / 原形質膜 / 水代謝 / 排泄 / カイコ / シロアリ / アクアポリン / 原形質膜機能 / 中腸 |
Research Abstract |
The regulation of body fluid composition and cellular and tissue osmolality through solute and water transport is fundamental for all terrestrial insects. Water transport across the plasma membrane is mediated through a water channel, called aquaporin (AQP), which regulates rapid water fluxes between cellular and tissue compartments. Advances in the functional characterization of AQPs in the vectorial fluid transport of liquid-feeding insects have led to the identification of three distinct AQPs in the digestive and excretory tissue of the silkworm, Bombyx mori. Evidence that several isoforms of AQP occur in one insect species is accumulating steadily. We have explored the physiological roles of the respective type of Bombyx AQP in other insect species such as the blowfly, the chafer larva and a termite. The molecular functional characterization of each AQP protein were explored to understand the physiological substrate (water only or further non-electrolyte solute) in each insect.
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Report
(4 results)
Research Products
(29 results)
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[Presentation] Aquaporins for water balance in Lepidopteran larvae2011
Author(s)
Masaaki Azuma
Organizer
Molecular Physiology of Epithelial Transport in Insects - A tribute to William R Harvey - Society for Experimental Biology Annual Main Meeting, 2011(招待講演)
Place of Presentation
Scottish Exhibition & Conference Centre (SECC at Glasgow, UK)
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