• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The effects of maternal exposure of persistent organochlorine pesticides on allergic and infection's symptoms in infancy

Research Project

Project/Area Number 23590769
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Public health/Health science
Research InstitutionHokkaido University (2012-2013)
Junior College, Asahikawa University (2011)

Principal Investigator

KANAZAWA Ayako  北海道大学, 環境健康科学研究教育センター, 客員研究員 (90201425)

Co-Investigator(Kenkyū-buntansha) HANDA Yasushi  北海道大学, 遺伝子病制御研究所, 客員研究員 (70571785)
MIYASHITA Chihiro  北海道大学, 環境健康科学研究教育センター, 特任助教 (70632389)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords母子保健 / ヒト次世代影響 / 難分解性有機塩素系農薬 / 喘息 / アトピー / 感染症
Research Abstract

Previous studies suggest that persistent organochlorine (POC) pesticides may contribute to endocrine disruption. The purpose of this study was to investigate the association between POCs levels in maternal blood and the risk of allergies in infancy. Between 2002 and 2005, 514 pregnant women were recruited in Sapporo Toho Hospital, and 29 POC pesticides in 320 whole blood samples were measured. No associations between POC pesticides levels and allergic symptoms at 18 month of age were observed in adjusted logistic regression analysis. At background levels, prenatal exposure to POC pesticides may alter immune function during childhood. Therefore, more long-term observations are needed to assess whether developmental exposure may result in allergic diseases in later childhood.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (24 results)

All 2014 2013 2012 2011 Other

All Journal Article (13 results) (of which Peer Reviewed: 11 results,  Open Access: 3 results) Presentation (6 results) Remarks (5 results)

  • [Journal Article] Association of Mechanical Ventilation and Flue Use in Heaters With Asthma Symptoms in Japanese Schoolchildren: A Cross-Sectional Study in Sapporo, Japan2014

    • Author(s)
      Cong S., Araki A., Ukawa S., Ait Bamai Y., Tajima S., Kanazawa A., Yuasa M., Tamakoshi A., Kishi R
    • Journal Title

      Journal of Epidemiology

      Volume: 24 Issue: 3 Pages: 230-238

    • DOI

      10.2188/jea.JE20130135

    • NAID

      130003392103

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Phosphorus flame retardants in indoor dust and their relation to asthma and allergies of inhabitants2014

    • Author(s)
      Araki A., Saito I., Kanazawa A., Morimoto K., Nakayama K., Shibata E., Tanaka M., Takigawa T., Yoshimura T., Chikara H., Saijo Y., Kishi R
    • Journal Title

      Indoor Air

      Volume: 24 Issue: 1 Pages: 3-15

    • DOI

      10.1111/ina.12054

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exposure to house dust phthalates in relation to asthma and allergies in both children and adults2014

    • Author(s)
      Ait Bamai Y., Shibata E., Saito I., Araki A., Kanazawa A., Morimoto K., Nakayama K., Tanaka M., Takigawa T., Yoshimura T., Chikara H., Saijo Y., Kishi R
    • Journal Title

      Sci Total Environ

      Volume: 485-486C Pages: 153-163

    • DOI

      10.1016/j.scitotenv.2014.03.059

    • NAID

      120005425358

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The association between mechanical ventilation, flue use in heaters and asthma symptoms in Japanese schoolchildren - A cross-sectional study in Sapporo, Japan2014

    • Author(s)
      Cong S., Araki A., Ukawa S., Ait Bamai Y., Tajima S., Kanazawa A., Yuasa M., Tamakoshi A., Kishi R.
    • Journal Title

      J Epidemiol

      Volume: in press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between atopic dermatitis and indoor environmental factors: a cross-sectional study among Japanese elementary school children2013

    • Author(s)
      Ukawa S, Araki A, Kanazawa A, Yuasa M, Kishi R
    • Journal Title

      Int Arch Occup Environ Health

      Volume: - Issue: 7 Pages: 777-787

    • DOI

      10.1007/s00420-012-0814-0

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Ten years of progress in the Hokkaido birth cohort study on environment and children's health : cohort profile--updated 2013.2013

    • Author(s)
      Kishi R, Kobayashi S, Ikeno T, Araki A, Miyashita C, Itoh S, Sasaki S, Okada E, Kobayashi S, Kashino I, Itoh K, Nakajima S ; Members of the Hokkaido Study on Environment and Children's Health.
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 18 Issue: 6 Pages: 429-450

    • DOI

      10.1007/s12199-013-0357-3

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 札幌市の小学生4,500名を対象とした住環境とアトピー性皮膚炎に関する調査2013

    • Author(s)
      鵜川重和, 荒木敦子, 金澤文子, 湯浅資之, 岸玲子
    • Journal Title

      北海道医学雑誌

      Volume: 88 Pages: 95-95

    • Related Report
      2013 Annual Research Report
  • [Journal Article] ハウスダスト中フタル酸エステルと住環境との関連2013

    • Author(s)
      アイツバマイゆふ, 荒木敦子, 河合俊夫, 坪井樹, 斎藤育江, 吉岡英治, 金澤文子, 多島秀司, 叢石, 玉腰暁子, 岸玲子
    • Journal Title

      北海道医学雑誌

      Volume: 88 Pages: 198-198

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Blood persistent organochlorine pesticides of pregnant women relating to their characteristics in the Hokkaido Study on environment and children's health2012

    • Author(s)
      Kanazawa A, Miyashita C, Okada E, Kobayashi S, Washino N, Sasaki S, Yoshioka E, Mizutani F, Chisaki Y, Saijo Y, Kishi R.
    • Journal Title

      Sci Total Environ.

      Volume: (In press) Pages: 73-82

    • DOI

      10.1016/j.scitotenv.2012.02.073

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between exposure to microbial volatile organic compound and allergy prevalence in single-family homes2012

    • Author(s)
      Araki A., Kanazawa A., Kawai T., Eitaki Y., Morimoto K., Nakayama K., Shibata E., Tanaka M., Takigawa T., Yoshimura T., Chikara H., Saijo Y., Kishi R
    • Journal Title

      Sci Total Environ

      Volume: 423 Pages: 18-26

    • DOI

      10.1016/j.scitotenv.2012.02.026

    • NAID

      120004027252

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between exposure to microbial volatile organic compound and allergy prevalence in single-family homes.2012

    • Author(s)
      Araki A, Kanazawa A, Kawai T, Eitaki Y, Morimoto K, Nakayama K, Shibata E, Tanaka M, Takigawa T, Yoshimura T, Chikara H, Saijo Y, Kishi R.
    • Journal Title

      Sci Total Environ

      Volume: 423 Pages: 18-26

    • NAID

      120004027252

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Blood persistent organochlorine pesticides in pregnant women in relation to physical and environmental variables in The Hokkaido Study on Environment and Children's Health.2012

    • Author(s)
      Kanazawa A, Miyasita C, Okada E, Kobayashi S, Washino N, Sasaki S, Yoshioka E, Mizutani F, Chisaki Y, Saijo Y, Kishi R.
    • Journal Title

      Sci Total Environ.

      Volume: 426 Pages: 73-82

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 北海道の妊婦の全血中POPs系農薬の濃度環境と子どもの健康に関する北海道研究2011

    • Author(s)
      金澤文子, 宮下ちひろ, 岡田恵美子, 小林澄貴, 鷲野孝揚, 湯浅資之, 佐々木成子, 吉岡英治, 水谷太, 苣木洋一, 岸玲子
    • Journal Title

      日本衛生学雑誌

      Volume: 66 Pages: 95-107

    • NAID

      10029363979

    • URL

      http://search.jamas.or.jp/link/ui/2011192746

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] 札幌市内小学生の自宅における暖房、および機械換気の有無と児童の喘息2013

    • Author(s)
      叢石, 荒木敦子, 鵜川重和, アイツバマイゆふ, 多島秀司, 金澤文子, et al
    • Organizer
      第65回北海道公衆衛生学会
    • Place of Presentation
      札幌
    • Related Report
      2013 Final Research Report
  • [Presentation] 尿中フタル酸代謝物濃度とハウスダスト中フタル酸エステル濃度との関連:札幌市児童における調査2013

    • Author(s)
      アイツバマイゆふ, 荒木敦子, 河合俊夫, 坪井樹, 多島秀司, 叢石, 湯浅資之, 金澤文子, et al
    • Organizer
      第65回北海道公衆衛生学会
    • Place of Presentation
      札幌
    • Related Report
      2013 Final Research Report
  • [Presentation] 札幌市内小学生の自宅における暖房、および機械換気の有無と児童の喘息2013

    • Author(s)
      叢石, 荒木敦子, 鵜川重和, アイツバマイゆふ, 多島秀司, 金澤文子, 湯浅資之, 玉腰暁子, 岸玲子
    • Organizer
      第65回北海道公衆衛生学会
    • Place of Presentation
      札幌市生涯学習センター ちえりあ(札幌)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 尿中フタル酸代謝物濃度とハウスダスト中フタル酸エステル濃度との関連:札幌市児童における調査2013

    • Author(s)
      アイツバマイゆふ, 荒木敦子, 河合俊夫, 坪井樹, 多島秀司, 叢石, 湯浅資之, 金澤文子, 玉腰暁子, 岸玲子
    • Organizer
      第65回北海道公衆衛生学会
    • Place of Presentation
      札幌市生涯学習センター ちえりあ(札幌)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 自宅住環境とアトピー性皮膚炎に関する調査-札幌市の小学生4,500名を対象として-2011

    • Author(s)
      鵜川重和, 荒木敦子, 金澤文子, et al
    • Organizer
      第63回北海道公衆衛生学会
    • Place of Presentation
      札幌
    • Related Report
      2013 Final Research Report
  • [Presentation] 自宅住環境とアトピー性皮膚炎に関する調査-札幌市の小学生4,500名を対象として.2011

    • Author(s)
      鵜川重和、荒木敦子、金澤文子、湯浅資之、アイツバマイゆふ、吉岡英治、叢石、 多島秀司、岸玲子
    • Organizer
      第63回北海道公衆衛生学会
    • Place of Presentation
      札幌市
    • Related Report
      2011 Research-status Report
  • [Remarks] 環境健康科学研究教育センターwebサイト研究業績

    • URL

      http://www.cehs.hokudai.ac.jp/research/yearly/

    • Related Report
      2013 Final Research Report
  • [Remarks] 環境健康科学研究教育センター成果発信webサイト「環境と健康ひろば」

    • URL

      http://www.cehs.hokudai.ac.jp/hiroba/

    • Related Report
      2013 Final Research Report
  • [Remarks] 環境健康科学研究教育センター 研究業績

    • URL

      http://www.cehs.hokudai.ac.jp/research/yearly/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 環境と健康ひろば

    • URL

      http://www.cehs.hokudai.ac.jp/hiroba/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 北海道大学環境健康科学研究教育センター

    • URL

      http://www.cehs.hokudai.ac.jp/index.html

    • Related Report
      2012 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi