The treatment for cedar pollinosis and atopic dermatitis by the local induction of IL-10
| Project/Area Number |
23591643
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Dermatology
|
|---|
| Research Institution | Mie University |
|---|
Principal Investigator |
Yamanaka Keiichi 三重大学, 医学(系)研究科(研究院), 准教授 (70314135)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
水谷 仁 三重大学, 医学(系)研究科(研究院), 教授 (30115737)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Keywords | 花粉症 / アレルギー / アトピー性皮膚炎 / IL-10 / IL-10産生型抑制性T細胞 / パラインフルエンザウイルス / 免疫療法 / スギ花粉症 |
|---|
| Outline of Final Research Achievements |
The major goal of this proposal is to investigate when and where IL-10 is produced by repeated Cry j1 and Cry j2 challenge. We had analyzed IL-10 expression using IL-10tm1Flv/J mice in which the cells express GFP when they produce IL-10.
|
Report
(4 results)
Research Products
(26 results)
-
-
[Journal Article] Novel acoustic evaluation system for scratching behavior in itching dermatitis: Rapid and accurate analysis for nocturnal scratching of atopic dermatitis patients.2014
Author(s)
Noro Y, Omoto Y, Umeda K, Tanaka F, Shiratsuka Y, Yamada T, Isoda K, Matsubara K, Yamanaka K, Gabazza EC, Nishikawa M, Mizutani H.
-
Journal Title
J Dermatol.
Volume: 41
Issue: 3
Pages: 233-238
DOI
Related Report
Peer Reviewed
-
-
[Journal Article] Intranasally administered antigen 85B gene vaccine in non-replicating human Parainfluenza type 2 virus vector ameliorates mouse atopic dermatitis.2013
Author(s)
Kitagawa H, Kawano M, Yamanaka K, Kakeda M, Tsuda K, Inada H, Yoneda M, Sakaguchi T, Nigi A, Nishimura K, Komada H, Tsurudome M, Yasutomi Y, Nosaka T, Mizutani H.
-
Journal Title
PLoS One.
Volume: 8
Issue: 7
Pages: 66614-66614
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
[Journal Article] Intratumoral Injection of Propionibacterium acnes Suppresses Malignant Melanoma by Enhancing Th1 Immune Responses.2011
Author(s)
Tsuda K, Yamanaka K, Linan W, Miyahara Y, Akeda T, Nakanishi T, Kitagawa H, Kakeda M, Kurokawa I, Shiku H, Gabazza EC, Mizutani H.
-
Journal Title
PLoS ONE
Volume: 6
Pages: 29020-29020
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
