Double Potential Mapping: Development of a novel method to verify conduction block

• Project/Area Number: 23592050
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Thoracic surgery
• Research Institution: Nippon Medical School
• Principal Investigator: NITTA Takashi 日本医科大学, 医学部, 教授 (40256954)
• Co-Investigator(Kenkyū-buntansha): ISHII Yosuke 日本医科大学, 医学部, 准教授 (10307895) ; SAKAMOTO Shun-ichiro 日本医科大学, 医学部, 講師 (50398872)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 高周波アブレーション / ダブルポテンシャル / 伝導ブロック

Research Abstract

Double potential mapping using bipolar electrodes that straddle the ablation line should identify the site of incomplete ablation as a conduction gap without constructing the activation maps.
Bipolar electrograms were recorded during pacing using 11 custom-made bipolar electrodes straddling the ablation line created by a bipolar radiofrequency ablation device on the lateral right atrium in seven canines. The lateral right atrium was mapped simultaneously with 45 different bipolar electrodes to construct the activation maps and the earliest activation site across the ablation line was determined. The double potential mapping located the conduction gap on a real-time basis without displaying any maps. There was no significant change in the accuracy between the different times after ablation and different pacing cycle lengths.
Double potential mapping locates the conduction gap on a real-time basis and would be useful in beating-heart epicardial ablation in off-pump setting.

Research Products

• [Journal Article] Double Potential Mapping: A Novel Technique for Locating the Site of Incomplete Ablation (2013)
  • Author(s): Nitta T, Wakita M, Watanabe Y, et al.
  • Journal Title: Innovations Volume: 7 Pages: 429-434
  • Peer Reviewed
• [Journal Article] Double potential mapping : A novel technique for locating the site of incomplete ablation (2012)
  • Author(s): Nitta T, Wakita M, Watanabe Y, Ohmori H, Sakamoto S, Ishii Y, Ochi M
  • Journal Title: Innovations Volume: 7 Pages: 429-434
• [Presentation] Double Potential Mapping : A Novel Technique for Locating the Site of Incomplete Ablation (2011)
  • Author(s): Wakita M, Nitta T, Watanabe Y, Sakamoto S, Ohmori H, Ishii Y, Ochi M, Shimizu K
  • Organizer: Tenth Annual Meeting ISMICS
• [Presentation] ダブルポテンシャルマッピング:心房自由壁の不完全焼灼部位検出の新しい方法 (2011)
  • Author(s): 新田隆、脇田真希、坂本俊一郎、渡邊嘉之、高橋賢一郎、田上素子、栗田二郎、大森裕也、藤井正大、織井恒安、落雅美、清水一雄
  • Organizer: 第64回日本胸部外科学会総会
• [Presentation] Double Potential Mapping: A Novel Technique ... (2011)
  • Author(s): Wakita M, Nitta T, Sakamoto S, et al
  • Organizer: 10th Annual Meeting of ISMICS
  • Place of Presentation: Washington, DC
• [Presentation] ダブルポテンシャルマッピング：心房自由壁の不完全焼灼部位検出の新しい方法 (2011)
  • Author(s): 新田 隆、脇田真希、坂本俊一郎、他
  • Organizer: 第64回日本胸部外科学会総会
  • Place of Presentation: 名古屋