Development of oncolytic virotherapy using live attenuated poliovirus for human bone and soft tissue sarcomas.

• Project/Area Number: 23592183
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: Mie University
• Principal Investigator: MATSUMINE Akihiko 三重大学, 医学(系)研究科(研究院), 准教授 (00335118)
• Co-Investigator(Kenkyū-buntansha): ASANUMA Kunihiro 三重大学, 大学院医学系研究科, 助教 (20378285) ; MATSUBARA Takao 三重大学, 医学系研究科, 講師 (30422827) ; NAKAMURA Tomoki 三重大学, 医学部附属病院, 助教 (50467362) ; TOYODA Hidemi 三重大学, 大学院医学系研究科, 助教 (60525327) ; KOMADA Yoshihiro 三重大学, 大学院医学系研究科, 教授 (80186791)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 弱毒化ポリオウイルス / 悪性骨軟部腫瘍 / 細胞融解療法 / CD155 / ポリオウイルス / ポリオ生ワクチン / 肉腫 / 細胞死 / アポトーシス / ポリオウイルスレセプター

Research Abstract

The poliovirus receptor CD155, is essential for poliovirus to induce cell-death in neural cells. Recently, CD155 has been shown to be selectively expressed on certain types of tumor cells originating from the neural crest. We first examined CD155 expression in sarcoma cell lines, and found the expression of CD155 in all of 10 sarcoma cell lines. Furthermore, we found that live-attenuated polio viruses (LAPV) induced apoptosis. In nude mice transplanted with HT1080, administration of live attenuated poliovirus caused growth suppression of the tumors. Next, the CD155 expression levels in 43 surgically resected soft tissue tumors were evaluated. The local recurrence free survival rate for patients with a high CD155 expression level was significantly poorer compared with that of patients with low CD155 expression levels.
These results suggest that oncolytic therapy using a LAPV may represent a new option for the treatment of sarcomas.

Research Products

• [Journal Article] Role of High-sensitivity C-reactive Protein in the Differentiation of Benign and Malignant Soft Tissue Tumors (2014)
  • Author(s): Nakamura T, Matsumine A, Iino T, Matsubara T, Asanuma K, Uchida A, Sudo A
  • Journal Title: Anticancer Res Volume: 34 Pages: 933-936
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=Role+of+High-sensitivity+C-reactive+Protein+in+the+Differentiation+of+Benign+and+Malignant+Soft+Tissue+Tumors
  • Peer Reviewed
• [Journal Article] Radiofrequency ablation for the treatment of recurrent bone and soft-tissue sarcomas in non-surgical candidates (2014)
  • Author(s): Yamakado K, Matsumine A, Nakamura T, Nakatsuka A, Takaki H, Matsubara T, Asanuma K, Sudo A, Sugimura Y, Sakuma H.
  • Journal Title: Int J Clin Oncol. Volume: 印刷中
  • DOI: 10.1007/s10147-013-0640-8
  • Peer Reviewed
• [Journal Article] Clinical outcomes of Kyocera Modular Limb Salvage system after resection of bone sarcoma of the distal part of the femur : the Japanese Musculoskeletal Oncology Group study (2013)
  • Author(s): Nakamura T, Matsumine A, Uchida A, Kawai A, Nishida Y, Kunisada T, Araki N, Sugiura H, Tomita M, Yokouchi M, Ueda T, Sudo A
  • Journal Title: Int Orthop
  • DOI: 10.1007/s00264-013-2151-7
  • Peer Reviewed
• [Journal Article] The combined use of the neutrophil-lymphocyte ratio and C-reactive protein level as prognostic predictors in adult patients with soft tissue sarcoma (2013)
  • Author(s): Nakamura T, Matsumine A, Matsubara T, Asanuma K, Uchida A, Sudo A.
  • Journal Title: J Surg Oncol. Volume: 108(7) Pages: 481-485
  • DOI: 10.1002/jso.23424
  • Peer Reviewed
• [Journal Article] Deep-vein thrombosis after resection of musculoskeletal tumours of the lower limb (2013)
  • Author(s): Yamaguchi T, Matsumine A, Niimi R, Nakamura T, Matsubara T, Asanuma K,Hasegawa M, Sudo A.
  • Journal Title: Bone Joint J. Volume: 95(9) Pages: 1280-1284
  • DOI: 10.1302/0301-620x.95b9.30905
  • Peer Reviewed
• [Journal Article] Ewing's sarcoma with an uncommon clinical course : A case report (2013)
  • Author(s): Niimi R, Matsumine A, Nakamura T, Morimoto R, Murata T, Suzuki T, Nakashima Y, Nojima T, Uchida A, Sudo A
  • Journal Title: Oncol Lett Volume: 6 Pages: 9-12
  • DOI: 10.3892/ol.2013.1320
  • Peer Reviewed
• [Journal Article] Prognostic significance of CD155 mRNA expression in soft tissue sarcomas (2013)
  • Author(s): Atsumi S, Matsumine A, Toyoda H, Niimi R, Iino T, Sudo A
  • Journal Title: Oncol Lett Volume: 5(6) Pages: 1771-1776
  • DOI: 10.3892/ol.2013.1280
  • Peer Reviewed
• [Journal Article] Soluble Neural-cadherin as a novel biomarker for malignant bone and soft tissue tumors (2013)
  • Author(s): Niimi R, Matsumine A, Iino T, Nakazora S, Nakamura T, Uchida A, Sudo A
  • Journal Title: BMC Cancer Volume: 26
  • DOI: 10.1186/1471-2407-13-309
  • Peer Reviewed
• [Journal Article] Clinical significance of radiofrequency ablation and metastasectomy in elderly patients with lung metastases from musculoskeletal sarcomas. (2013)
  • Author(s): Nakamura T, Matsumine A, Yamakado K, Takao M, Uchida A, Sudo A
  • Journal Title: J Cancer Res Ther. Volume: 9(2)(PMID:23771362, PubMed - indexed for MEDLINE) Pages: 219-223
  • DOI: 10.4103/0973-1482.113358
  • Peer Reviewed
• [Journal Article] Can a less radical surgery using photodynamic therapy with acridine orange be equal to a wide-margin resection? (2013)
  • Author(s): Matsubara T, Kusuzaki K, Matsumine A, Nakamura T, Sudo A.
  • Journal Title: Clin Orthop Relat Res. Volume: 471(3) Pages: 729-802
  • DOI: 10.1007/s11999-012-2616-9
  • Peer Reviewed
• [Journal Article] The thrombin inhibitor, argatroban, inhibits breast cancer metastasis to bone (2013)
  • Author(s): Asanuma K, Wakabayashi H, Okamoto T, Asanuma Y, Akita N, Yoshikawa T, Hayashi T, Matsumine A, Uchida A, Sudo A.
  • Journal Title: Breast Cancer Volume: 20(3) Pages: 241-246
  • DOI: 10.1007/s12282-012-0334-5
  • NAID: 10031202704
  • Peer Reviewed
• [Journal Article] Ewing's sarcoma with an uncommon clinical course: A case report. (2013)
  • Author(s): Niimi R, Matsumine A, Nakamura T, Morimoto R, Murata T, Suzuki T, Nakashima Y,
  • Journal Title: Oncol Let Volume: 6(1) Pages: 9-12
  • Peer Reviewed
• [Journal Article] Soluble Neural-cadherin as a novel biomarker for malignant bone and soft tissue tumors. (2013)
  • Author(s): Niimi R, Matsumine A, Iino T, Nakazora S, Nakamura T, Uchida A, Sudo A.
  • Journal Title: BMC Cancer Volume: 26;13(1) Pages: 309-309
  • Peer Reviewed
• [Journal Article] Prognostic significance of CD155 mRNA expression in soft tissue sarcomas. (2013)
  • Author(s): Atsumi S, Matsumine A, Toyoda H, Niimi R, Iino T, Sudo A.
  • Journal Title: Oncol Lett Volume: 5(6) Pages: 1771-1776
  • Peer Reviewed
• [Journal Article] Novel p53 splicing site mutation in Li-Fraumeni-like syndrome with osteosarcoma. (2013)
  • Author(s): Sakurai N, Iwamoto S, Miura Y, Nakamura T, Matsumine A, Nishioka J, Nakatani K, Komada Y.
  • Journal Title: Pediatr Int Volume: 55(1) Pages: 107-111
  • DOI: 10.1111/j.1442-200x.2012.03641.x
  • Peer Reviewed
• [Journal Article] Neoadjuvant and adjuvant chemotherapy with high-dose ifosfamide, doxorubicin, cisplatin and high-dose methotrexate in non-metastatic osteosarcoma of the extremities: a phase II trial in Japan. (2013)
  • Author(s): Kudawara I
  • Journal Title: J Chemother Volume: 25 Pages: 41-48
  • DOI: 10.1179/1973947812y.0000000055
  • Peer Reviewed
• [Journal Article] 骨軟部腫瘍手術でFondaparinuxを使用した13例の検討 (2013)
  • Author(s): 淺沼邦洋、松峯昭彦、松原孝夫、中村知樹、長谷川正裕、須藤啓広
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 56(2) Pages: 497-498
  • NAID: 10031174953
  • Peer Reviewed
• [Journal Article] 橈骨遠位骨巨細胞腫による骨変形で生じた長母指伸筋腱断裂の1例 (2013)
  • Author(s): 塚本 正、辻井雅也、植村 剛、松峯昭彦、須藤啓広、森本政司
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 56(3) Pages: 601-602
  • NAID: 10031188808
  • Peer Reviewed
• [Journal Article] コンパートメント症候群様症状で発症した悪性リンパ腫の1例 (2013)
  • Author(s): 伊東直也、松峯昭彦、竹上徳彦、辻井雅也、須藤啓広
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 56(5) Pages: 1159-1160
  • NAID: 130004144044
  • Peer Reviewed
• [Journal Article] 【転移性肺腫瘍の外科治療】 骨・軟部悪性腫瘍肺転移例に対する治療 (2013)
  • Author(s): 天白宏典、高尾仁二、島本 亮、村嶋秀市、山門亨一郎、中村知樹、松峯昭彦、新保秀人
  • Journal Title: 胸部外科 Volume: 66(4) Pages: 311-314
  • Peer Reviewed
• [Journal Article] Clinical significance of pretreatment serum C-reactive protein level in soft tissue sarcoma. (2012)
  • Author(s): Nakamura T, Matsumine A, Matsubara T, Asanuma K, Uchida A, Sudo A
  • Journal Title: Cancer. Volume: 118(4) Pages: 1055-1061
  • DOI: 10.1002/cncr.26353
  • Peer Reviewed
• [Journal Article] Translational research of photodynamic therapy with acridine orange which targets cancer acidity. (2012)
  • Author(s): Kusuzaki K, Hosogi S, Ashihara E, Matsubara T, Satonaka H, Nakamura T, Matsumine A, Sudo A, Uchida A, Murata H, Baldini N, Fais S, Marunaka Y.
  • Journal Title: Curr Pharm Des Volume: 18 Pages: 1414-1420
  • DOI: 10.2174/138161212799504812
  • Peer Reviewed
• [Journal Article] Prosthetic limb salvage surgery for bone and soft tissue tumors around the knee (2012)
  • Author(s): Niimi R, Matsumine A, Hamaguchi T, Nakamura T, Uchida A, Sudo A.
  • Journal Title: Oncol Rep Volume: 28(6) Pages: 1984-1990
  • DOI: 10.3892/or.2012.2021
  • Peer Reviewed
• [Journal Article] Oncolytic virotherapy for human bone and soft tissue sarcomas using live attenuated poliovirus (2012)
  • Author(s): Atsumi S, Matsumine A, Toyoda H, Niimi R, Iino T, Nakamura T, Matsubara T, Asanuma K, Komada Y, Uchida A, Sudo A.
  • Journal Title: Int J Oncol Volume: 41(3) Pages: 893-902
  • DOI: 10.3892/ijo.2012.1514
  • Peer Reviewed
• [Journal Article] A novel hyperthermia treatment for bone metastases using magnetic materials (2011)
  • Author(s): Matsumine A, Takegami K, Asanuma K, Matsubara T, Nakamura T, Uchida A, Sudo A
  • Journal Title: Int J Clin Oncol Volume: 16 Pages: 101-108
  • NAID: 10029366305
  • Peer Reviewed
• [Journal Article] Japanese Musculoskeletal Oncology Group. Clinical outcomes of the KYOCERA Physio Hinge Total Knee System Type III after the resection of a bone and soft tissue tumor of the distal part of the femur. (2011)
  • Author(s): Matsumine A, Ueda T, Sugita T, Yazawa Y, Isu K, Kawai A, Abe S, Yakushiji T, Hiraga H, Sudo A, Uchida A
  • Journal Title: J Surg Oncol. Volume: 103(3) Pages: 257263-257263
  • DOI: 10.1002/jso.21823
  • Peer Reviewed
• [Journal Article] The adverse effect of an unplanned surgical excision of foot soft tissue sarcoma (2011)
  • Author(s): Nishimura A, Matsumine A, Asanuma K, Matsubara T, Nakamura T, Uchida A, Kato K, Sudo A
  • Journal Title: World J Surg Oncol Volume: 9 Pages: 160-160
  • DOI: 10.1186/1477-7819-9-160
  • Peer Reviewed
• [Journal Article] Transfection of NF-κB decoy oligodeoxynucleotide suppresses pulmonary metastasis by murine osteosarcoma (2011)
  • Author(s): Nishimura A, Akeda K, Matsubara T, Kusuzaki K, Matsumine A, Masuda K, Gemba T, Uchida A, Sudo A
  • Journal Title: Cancer Gene Ther Volume: 18(4) Pages: 250-259
  • DOI: 10.1038/cgt.2010.75
  • Peer Reviewed
• [Journal Article] Recurrent ankle equinus deformity due to intramuscular hemangioma of the gastrocnemius : case report (2011)
  • Author(s): Nakamura T, Matsumine A, Nishiyama M, Uchida A, Sudo A
  • Journal Title: Foot Ankle Int Volume: 32 Pages: 905-907
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=Recurrent+ankle+equinus+deformity+due+to+intramuscular+hemangioma+of+the+gastrocnemius%3A+case+report
  • Peer Reviewed
• [Journal Article] Clinical impact of the tumor volume doubling time on sarcoma patients with lung metastases (2011)
  • Author(s): Nakamura T, Matsumine A, Matsubara T, Asanuma K, Uchida A, Sudo A
  • Journal Title: Clin Exp Metastasis Volume: 28 Pages: 819-825
  • DOI: 10.1007/s10585-011-9413-9
  • Peer Reviewed
• [Journal Article] The symptom-to-diagnosis delay in soft tissue sarcoma influence the overall survival and the development of distant metastasis (2011)
  • Author(s): Nakamura T, Matsumine A, Matsubara T, Asanuma K, Uchida A, Sudo A
  • Journal Title: J Surg Oncol. Volume: 104(7) Pages: 771-5
  • DOI: 10.1002/jso.22006
  • Peer Reviewed
• [Journal Article] Extraslkeletal subcutaneous osateosarcoma of the upper arm : A case report (2011)
  • Author(s): Nakamura T, Matsumine A, Nishimura K, Yokoyama H, Murata T, Uchida A, Sudo A
  • Journal Title: Oncology Letters Volume: 2 Pages: 75-77
  • DOI: 10.3892/ol.2010.204
  • Peer Reviewed
• [Journal Article] Retrospective analysis of metastatic sarcoma patients (2011)
  • Author(s): Nakamura T, Matsumine A, Matsubara T, Asanuma K, Niimi R, Uchida A, Sudo A
  • Journal Title: Oncology Letters Volume: 2 Pages: 315-318
  • DOI: 10.3892/ol.2011.238
  • Peer Reviewed
• [Journal Article] Acridine orange inhibits pulmonary metastasis of mouse osteosarcoma (2011)
  • Author(s): Satonaka H, Kusuzaki K, Akeda K, Tsujii M, Iino T, Uemura T, Matsubara T, Nakamura T, Asanuma K, Matsumine A, Sudo A
  • Journal Title: Anticancer Res Volume: 31 Pages: 4163-4168
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=Acridine+orange+inhibits+pulmonary+metastasis+of+mouse+osteosarcoma
  • Peer Reviewed
• [Journal Article] TNF inhibitor suppresses bone metastasis in a breast cancer cell line (2011)
  • Author(s): Hamaguchi T, Wakabayashi H, Matsumine A, Sudo A, Uchida A
  • Journal Title: Biochem Biophys Res Commun Volume: 407 Pages: 525-530
  • DOI: 10.1016/j.bbrc.2011.03.051
  • Peer Reviewed
• [Journal Article] Acridine orange inhibits pulmonary metastasis of mouse osteosarcoma. (2011)
  • Author(s): Satonaka H, Kusuzaki K, Akeda K, Tsujii M, Iino T, Uemura T, Matsubara T, Nakamura T, Asanuma K, Matsumine A, Sudo A.
  • Journal Title: Anticancer Res. Volume: 31(12) Pages: 4163-8
  • Peer Reviewed
• [Journal Article] The adverse effect of an unplanned surgical excision of foot soft tissue sarcoma. (2011)
  • Author(s): Nishimura A, Matsumine A, Asanuma K, Matsubara T, Nakamura T, Uchida A, Kato K, Sudo A.
  • Journal Title: World J Surg Oncol. Volume: 9 Pages: 160-160
  • Peer Reviewed
• [Journal Article] Recurrent ankle equinus deformity due to intramuscular hemangioma of the gastrocnemius: case report. (2011)
  • Author(s): Nakamura T, Matsumine A, Nishiyama M, Uchida A, Sudo A.
  • Journal Title: Foot Ankle Int. Volume: 32(9) Pages: 905-7
  • Peer Reviewed
• [Journal Article] Clinical impact of the tumor volume doubling time on sarcoma patients with lung metastases. (2011)
  • Author(s): Nakamura T, Matsumine A, Matsubara T, Asanuma K, Uchida A, Sudo A.
  • Journal Title: Clin Exp Metastasis. Volume: 28(8) Pages: 819-25
  • Peer Reviewed
• [Journal Article] TNF inhibitor suppresses bone metastasis in a breast cancer cell line. (2011)
  • Author(s): Hamaguchi T, Wakabayashi H, Matsumine A, Sudo A, Uchida A.
  • Journal Title: Biochem Biophys Res Commun. Volume: 407(3) Pages: 525-30
  • Peer Reviewed
• [Journal Article] A novel hyperthermia treatment for bone metastases using magnetic materials. (2011)
  • Author(s): Matsumine A, Takegami K, Asanuma K, Matsubara T, Nakamura T, Uchida A, Sudo A.
  • Journal Title: Int J Clin Oncol. Volume: 16(2) Pages: 101-8
  • NAID: 10029366305
  • Peer Reviewed
• [Journal Article] 環椎溶骨性変化に斜頸を合併したspinal osseous epidural AVFの1例. (2011)
  • Author(s): 奥野一真, 松原孝夫, 中村知樹, 浅沼邦洋, 松峯昭彦, 須藤啓広.
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 54(1) Pages: 147-148
  • Peer Reviewed
• [Journal Article] 当院における高齢者骨肉腫の予後規定因子の検討. (2011)
  • Author(s): 淺沼邦洋, 松峯昭彦, 松原孝夫, 中村知樹, 内田淳正, 須藤啓広
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 54(1) Pages: 81-82
  • NAID: 10029071256
  • Peer Reviewed
• [Journal Article] 下肢骨軟部腫瘍術後の深部静脈血栓症の発生率. (2011)
  • Author(s): 山口敏郎, 松峯昭彦, 長谷川正裕, 中村知樹, 須藤啓広 .
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 54(1) Pages: 79-80
  • NAID: 10029071248
  • Peer Reviewed
• [Journal Article] 骨肉腫・ユーイング肉腫に対するアクリジンオレンジ光線および放射線力学的療法の治療成績. (2011)
  • Author(s): 松原孝夫, 楠崎克之, 中村知樹, 松峯昭彦, 内田淳正, 須藤啓広 .
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 54(1) Pages: 73-74
  • NAID: 10029071238
  • Peer Reviewed
• [Journal Article] 肺転移に対しGemcitabineが有効であった骨肉腫の1例. (2011)
  • Author(s): 松原孝夫, 楠崎克之, 中村知樹, 松峯昭彦, 内田淳正, 須藤啓広 .
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 54(1) Pages: 59-60
  • NAID: 10029071197
  • Peer Reviewed
• [Journal Article] 軟部肉腫における不適切切除後の広範切除症例に対するMRIの有効性 (2011)
  • Author(s): 中村知樹, 松峯昭彦, 松原孝夫, 浅沼邦洋, 須藤啓広 .
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 54(1) Pages: 39-40
  • NAID: 10029071134
  • Peer Reviewed
• [Journal Article] 骨外性粘液型軟骨肉腫の治療成績． (2011)
  • Author(s): 中村知樹, 松峯昭彦, 松原孝夫, 淺沼邦洋, 楠崎克之, 須藤啓広
  • Journal Title: 整形外科 Volume: 62(6) Pages: 513-516
  • Peer Reviewed
• [Journal Article] 軟部腫瘍と鑑別を要した痛風結節の4例． (2011)
  • Author(s): 奥野一真, 中村知樹, 松原孝夫, 浅沼邦洋, 松峯昭彦, 須藤啓広．
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 54(4) Pages: 761-762
  • NAID: 10029661651
  • Peer Reviewed
• [Journal Article] 悪性骨軟部腫瘍における腫瘍細胞外pHと予後の検討． (2011)
  • Author(s): 松原孝夫, 楠崎克之, 中村知樹, 浅沼邦洋, 松峯昭彦, 須藤啓広．
  • Journal Title: 中部日本整形外科災害外科学会雑誌 Volume: 54(4) Pages: 745-746
  • NAID: 10029661608
  • Peer Reviewed
• [Presentation] Acridine Orange Therapy as a New Less-invasive Surgery for Recurrent or Aggressive Giant Cell Tumor of Bone (2014)
  • Author(s): Matsubara T, Kusuzaki K, Matsumine A, Asanuma K, Nakamura T, Sudo A
  • Organizer: American Academy of Orthopaedic Surgeons
  • Place of Presentation: New Orleans, USA
• [Presentation] Soluble N-cadherin as a Biomarker for Malignant Bone and Soft Tissue Tumors (2014)
  • Author(s): Matsumine A, Niimi R, Iino T, Nakamura T, Matsubara T, Asanuma K, Sudo A
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: New Orleans, USA
• [Presentation] Soluble cd155 As A Biomarker For Malignant Bone And Soft Tissue Tumors (2014)
  • Author(s): Goto M, Matsumine A, Nakamura T, Matsubara T, Asanuma K, Oi T, Sudo A
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: New Orleans, USA
• [Presentation] Carbonic Anhydrase iX has the Potential to Predict Preoperative chemotherapy effect (2014)
  • Author(s): Okuno K, Matsubara T, Matsumine A, Asanuma K, Nakamura T, Goto M, Oi T, Sudo A
  • Organizer: On human Osteosarcoma Patients. Orthopaedic Research Society
  • Place of Presentation: New Orleans, USA
• [Presentation] Cucurbitacin i (jsi-124) induces Apoptosis in human Osteosarcoma cells (2014)
  • Author(s): Oi T, Asanuma K, Nakamura T, Matsubara T, Matsumine A, Sudo A
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: New Orleans, USA
• [Presentation] Tumor Microenvironmental Factors and Acridine Orange intensity can Predict clinical Outcome in Soft Tissue Sarcoma Patients (2014)
  • Author(s): Matsubara T, Kusuzaki K, Matsumine A, Asanuma K, Nakamura T, Okuno K, Goto M, Oi T, Sudo A
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: New Orleans, USA
• [Presentation] The expression of Tissue Factor mRNA in bone and soft tissue sarcoma patients (2013)
  • Author(s): Asanuma K, Matsumine A, Matsubara T, Nakamura T, Ooi T, Asanuma Y, Sudo A
  • Organizer: European Musculo-Skeletal Oncolory Society
  • Place of Presentation: Gothenburg, Swedwn
• [Presentation] Clinical outcomes in the oldest old patients (85 years or old) with musuculoskeletal sarcomas (2013)
  • Author(s): Ooi T, Matsumine A, Goto M, Nakamura T, Matsubara T, Asanuma K, Sudo A
  • Organizer: European Musculo-Skeletal Oncolory Society
  • Place of Presentation: Gothenburg, Swedwn
• [Presentation] Acridine Orange Therapy as a New Less-invasive Limb Salvage Surgery for Rhabdomyosarcomas and Synovial Sarcomas (2013)
  • Author(s): Matsubara T, Kusuzaki K, Matsumine A, Asanuma K, Nakamura T, Sudo A
  • Organizer: American Academy of Orthopaedic Surgeons
  • Place of Presentation: Chicago, USA
• [Presentation] C-reactive Protein Level May be a Marker of Tumor Aggressiveness in Soft Tissue Sarcoma Patients (2013)
  • Author(s): Nakamura T, Matsumine A, Matsubara T, Asanuma K, Sudo A
  • Organizer: American Academy of Orthopaedic Surgeons
  • Place of Presentation: Chicago, USA
• [Presentation] Thrombomodulin and Tissue Factor mRNA Expression in 62 Soft Tissue Sarcoma Patients (2013)
  • Author(s): Asanuma K, Matsumine A, Matsubara T, Nakamura T, Yoshikawa T, Sudo A
  • Organizer: American Academy of Orthopaedic Surgeons
  • Place of Presentation: Chicago, USA
• [Presentation] Analysis of Tumor Metastatic Factor Using Coagulation Activity Model in Mice (2013)
  • Author(s): Asanuma K, Matsumine A, Asanuma Y, Akita N, Yoshikawa T, Matsubara T, Nakamura T, Okamoto T, Sudo A
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: San Antonio, USA
• [Presentation] New hyperthermic treatment with magnetic materials for metastatic bone tumor. (2013)
  • Author(s): Matsumine A, Matsubara T, Asanuma K, Nakamura T, Takegami K, Sudo A.
  • Organizer: 26th European Musculo-Skeletal Oncolory Society
  • Place of Presentation: Gothenburg, Swedwn
• [Presentation] The expression of Tissue Factor mRNA in bone and soft tissue sarcoma patients. (2013)
  • Author(s): Asanuma K, Matsumine A, Matsubara T, Nakamura T, Ooi T, Asanuma Y, Sudo A.
  • Organizer: 26th European Musculo-Skeletal Oncolory Society
  • Place of Presentation: Gothenburg, Swedwn
• [Presentation] Less Radical Resection for Tissue Sarcomas Combined with Chemotherapy and Acridine Orange Photodynamic Therapy Produced Excellent Local Control. (2013)
  • Author(s): Matsubara T, Kusuzaki K, Matsumine A, Asanuma K, Nakamura T, Uchida A, Sudo A.
  • Organizer: 26th European Musculo-Skeletal Oncolory Society
  • Place of Presentation: Gothenburg, Swedwn
• [Presentation] Clinical outcomes in the oldest old patients (85 years or old) with musuculoskeletal sarcomas. (2013)
  • Author(s): Ooi T, Matsumine A, Goto M, Nakamura T, Matsubara T, Asanuma K, Sudo A.
  • Organizer: 26th European Musculo-Skeletal Oncolory Society
  • Place of Presentation: Gothenburg, Swedwn
• [Presentation] Granular cell tumors of soft tissue :A report of five cases. (2013)
  • Author(s): Goto M, Matsumine A, Asanuma K, Matsubara T, Nakamura T, Ooi T, Sudo A.
  • Organizer: 26th European Musculo-Skeletal Oncolory Society
  • Place of Presentation: Gothenburg, Swedwn
• [Presentation] Clinical outcomes of revision surgery for failed tumor prostheses. (2013)
  • Author(s): Matsumine A, Asanuma K, Matsubara T, Nakamura T, Ooi T, Goto M, Sudo A.
  • Organizer: International Society of Limb Salvage 17th General Meeting
  • Place of Presentation: Bologna, Italy
• [Presentation] Clinical outcome of the KLS total Knee system after resection of bone sarcomas of the distal part of the femur: Japanese musculoskeletal oncology group (JMOG) study. (2013)
  • Author(s): Nakamura T, Matsumine A, Uchida A, Kawai A, Nishida Y, Kunisada T, Araki N, Sugiura H, Ueda T, Sudo A.
  • Organizer: International Society of Limb Salvage 17th General Meeting
  • Place of Presentation: Bologna, Italy
• [Presentation] 骨軟部肉腫に他悪性腫瘍を合併した多重癌の検討 (2013)
  • Author(s): 浅沼邦洋、松峯昭彦、松原孝夫、中村知樹、大井徹、須藤啓広
  • Organizer: 第120回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 和歌山市
• [Presentation] 化学療法感受性腫瘍に対するアクリジンオレンジ療法の検討 (2013)
  • Author(s): 松原孝夫、楠崎克之、松峯昭彦、浅沼邦洋、中村知樹、須藤啓広
  • Organizer: 第120回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 和歌山市
• [Presentation] 腫瘍切除後に自家処理骨を用いて再建を行った大腿骨骨幹部Ewing肉腫の治療成績 (2013)
  • Author(s): 中村知樹、Abudu Adesegun、松峯昭彦、松原孝夫、浅沼邦洋、須藤啓広
  • Organizer: 第120回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 和歌山市
• [Presentation] 上腕骨近位原発性骨悪性腫瘍に対する治療成績 (2013)
  • Author(s): 大井 徹、中村知樹、松原孝夫、浅沼邦洋、松峯昭彦、須藤啓広
  • Organizer: 第120回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 和歌山市
• [Presentation] 肋骨原発悪性骨腫瘍の治療成績 (2013)
  • Author(s): 後藤幹伸、松峯昭彦、中村知樹、松原孝夫、浅沼邦洋、須藤啓広
  • Organizer: 第120回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 和歌山市
• [Presentation] コンパートメント症候群様症状で発症した悪性リンパ腫の1例 (2013)
  • Author(s): 伊東直也、松峯昭彦、竹上德彦、辻井雅也、須藤啓広
  • Organizer: 第120回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 和歌山市
• [Presentation] アクリジンオレンジ治療法 (2013)
  • Author(s): 楠崎克之、松原孝夫、松峯昭彦、須藤啓広
  • Organizer: 第86回日本整形外科学会学術総会
  • Place of Presentation: 広島市
• [Presentation] 骨腫瘍に対する磁性体温熱療法 (2013)
  • Author(s): 松峯昭彦、淺沼邦洋、松原孝夫、中村知樹、後藤幹伸、大井 徹、須藤啓広
  • Organizer: 第86回日本整形外科学会学術総会
  • Place of Presentation: 広島市
• [Presentation] 高悪性軟部腫瘍に対するアクリジンオレンジ療法の検討 (2013)
  • Author(s): 松原孝夫、楠崎克之、松峯昭彦、淺沼邦洋、中村知樹、内田淳正、須藤啓広
  • Organizer: 第86回日本整形外科学会学術総会
  • Place of Presentation: 広島市
• [Presentation] 地域在住高齢者に対するロコモ25とロコモティブシンドロームとの関係 (2013)
  • Author(s): 西村明展、松峯昭彦、長谷川正裕、若林弘樹、明田浩司、淺沼邦洋、辻井雅也、里中東彦、松原孝夫、加藤公、須藤啓広
  • Organizer: 第86回日本整形外科学会学術総会
  • Place of Presentation: 広島市
• [Presentation] 脊椎椎体骨折の追跡調査―既存骨折に対する新規骨折の発生様式― (2013)
  • Author(s): 加藤俊宏、明田浩司、西村明展、松峯昭彦、長谷川正裕、若林弘樹、辻井雅也、淺沼邦洋、松原孝夫、中村知樹、須藤啓広
  • Organizer: 第86回日本整形外科学会学術総会
  • Place of Presentation: 広島市
• [Presentation] 腫瘍用人工関節再置換の手技的問題点－感染症例に対する治療を中心に－ (2013)
  • Author(s): 松峯昭彦、淺沼邦洋、松原孝夫、中村知樹、大井 徹、後藤幹伸、須藤啓広
  • Organizer: 第46回日本整形外科学会骨・軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 膝蓋骨-膝蓋腱-脛骨近位の術中加温/放射線処理により膝伸展機構を再建した膝前面軟部肉腫の3例 (2013)
  • Author(s): 松峯昭彦、辻井雅也、植村 剛、松原孝夫、淺沼邦洋、中村知樹、大井 徹、後藤幹伸、須藤啓広
  • Organizer: 第46回日本整形外科学会骨・軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 骨・軟部腫瘍手術でDVT予防の抗凝固療法は必要か (2013)
  • Author(s): 淺沼邦洋、松峯昭彦、山口敏郎、長谷川正裕、松原孝夫、中村知樹、宮本 憲、須藤啓広
  • Organizer: 第46回日本整形外科学会骨・軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 軟部肉腫に対するアクリジンオレンジ療法および術前化学療法兼用療法の治療成績 (2013)
  • Author(s): 松原孝夫、楠崎克之、松峯昭彦、淺沼邦洋、中村知樹、内田淳正、須藤啓広
  • Organizer: 第46回日本整形外科学会骨・軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 多発肺転移に対してラジオ波焼灼術を行い長期生存が得られている軟骨肉腫の1例 (2013)
  • Author(s): 中村知樹、松峯昭彦、松原孝夫、淺沼邦洋、須藤啓広
  • Organizer: 第46回日本整形外科学会骨・軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 超高齢発症の悪性骨・軟部腫瘍の治療成績 (2013)
  • Author(s): 大井 徹、松峯昭彦、後藤幹伸、中村知樹、松原孝夫、淺沼邦洋、須藤啓広
  • Organizer: 第46回日本整形外科学会骨・軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 血清可溶型CD155量は、悪性骨・軟部腫瘍患者の予後予測に有用である (2013)
  • Author(s): 後藤幹伸、松峯昭彦、淺沼邦洋、松原孝夫、中村知樹、大井 徹、須藤啓広
  • Organizer: 第46回日本整形外科学会骨・軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 転移性骨・軟部腫瘍に対するCT透視下凍結療法の初期経験 (2013)
  • Author(s): 中塚豊真、山門享一郎、高木治行、浦城淳二、山中隆嗣、藤森将志、長谷川貴章、佐久間肇、松峯昭彦、須藤啓広
  • Organizer: 第46回日本整形外科学会骨・軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 右胸壁に生じた放射線皮膚潰瘍に対して対側の内胸動脈穿通枝皮弁で加療した1例 (2013)
  • Author(s): 横山弘和、辻井雅也、國分直樹、大角秀彦、松峯昭彦、須藤啓広
  • Organizer: 日本マイクロサージャリー学会40周年記念学術集会
  • Place of Presentation: 盛岡市
• [Presentation] 放射線処理脛骨の近位骨端線離開に対して逆行性血管柄付き大腿骨内顆骨弁を施行した1例 (2013)
  • Author(s): 萩 智仁、辻井雅也、里中東彦、植村 剛、國分直樹、横山弘和、松峯昭彦、須藤啓広
  • Organizer: 日本マイクロサージャリー学会40周年記念学術集会
  • Place of Presentation: 盛岡市
• [Presentation] 軟部腫瘍における血中fibrinogen値の検討 (2013)
  • Author(s): 淺沼邦洋、中村知樹、松峯昭彦、松原孝夫、大井 徹、須藤啓広
  • Organizer: 第121回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 名古屋市
• [Presentation] 長管骨難治性骨巨細胞腫の治療成績 (2013)
  • Author(s): 松原孝夫、松峯昭彦、淺沼邦洋、中村知樹、奥野一真、須藤啓広
  • Organizer: 第121回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 名古屋市
• [Presentation] 肺転移に対してラジオ波焼灼術を行った高齢者（65歳以上）骨軟部肉腫の治療成績 (2013)
  • Author(s): 中村知樹、松峯昭彦、山門享一郎、松原孝夫、淺沼邦洋、須藤啓広
  • Organizer: 第121回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 名古屋市
• [Presentation] 超高齢発症の四肢悪性軟部腫瘍の治療成績 (2013)
  • Author(s): 大井 徹、松峯昭彦、淺沼邦洋、松原孝夫、中村知樹、須藤啓広
  • Organizer: 第121回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 名古屋市
• [Presentation] 肋骨を合併切除した胸壁発生軟部肉腫5例の治療成績 (2013)
  • Author(s): 後藤幹伸、松峯昭彦、中村知樹、松原孝夫、淺沼邦洋、須藤啓広
  • Organizer: 第121回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 名古屋市
• [Presentation] 骨外病変を伴った大腿骨近位悪性骨腫瘍における腫瘍用人工関節置換術後の患肢機能の検討 (2013)
  • Author(s): 奥野一真、松原孝夫、中村知樹、淺沼邦洋、松峯昭彦、須藤啓広
  • Organizer: 第121回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 名古屋市
• [Presentation] 上腕皮下に発生した骨外性骨肉腫の1例 (2013)
  • Author(s): 浅野貴裕、中村知樹、松原孝夫、淺沼邦洋、松峯昭彦、須藤啓広
  • Organizer: 第121回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 名古屋市
• [Presentation] 骨腫瘍と鑑別を要した特発性大腿骨頭壊死症の一例 (2013)
  • Author(s): 宮村 岳、長谷川正裕、吉田格之進、若林弘樹、松峯昭彦、須藤啓広
  • Organizer: 第121回中部日本整形外科災害外科学会学術集会
  • Place of Presentation: 名古屋市
• [Presentation] 薬物ライブラリを用いた骨肉腫に対する新規治療薬の探索 (2013)
  • Author(s): 大井 徹、淺沼邦洋、松峯昭彦、松原孝夫、中村知樹、飯野隆大、後藤幹伸、須藤啓広
  • Organizer: 第28回日本整形外科学会基礎学術集会
  • Place of Presentation: 千葉市
• [Presentation] 肉腫細胞においてCD155は細胞外に分泌されており、悪性骨･軟部腫瘍患者の有用なバイオマーカーとなりうる (2013)
  • Author(s): 後藤幹伸、松峯昭彦、飯野隆大、大井 徹、中村知樹、松原孝夫、淺沼邦洋、須藤啓広
  • Organizer: 第28回日本整形外科学会基礎学術集会
  • Place of Presentation: 千葉市
• [Presentation] 悪性骨･軟部腫瘍における血清中EXT1タンパクの意義 (2013)
  • Author(s): 飯野隆大、松峯昭彦、後藤幹伸、淺沼邦洋、松原孝夫、中村知樹、須藤啓広
  • Organizer: 第28回日本整形外科学会基礎学術集会
  • Place of Presentation: 千葉市
• [Presentation] 悪性軟部腫瘍に対するパゾパニブの治療効果 (2013)
  • Author(s): 松峯昭彦
  • Organizer: 第51回日本癌治療学会学術集会
  • Place of Presentation: 京都市
• [Presentation] Soluble N-cadherin as a Biomarker for Malignant Bone and Soft Tissue Tumor (2012)
  • Author(s): Matsumine A, Niimi R, Iino T, Nakazora S, Nakamura T, Matsubara T, Asanuma K, Uchida A, Sudo A
  • Organizer: 17) 9TH ASIS PACIFIC MUSCULOSKELETAL TUMOR SOCIETY MEETING 2012 Connectine Tissue Oncology Society
  • Place of Presentation: Czech Republic, Prague
• [Presentation] The Expression of Thrombomodulin Messenger RNA in 62 Soft Tissue Sarcoma Patients (2012)
  • Author(s): Asanuma K, Matsumine A, Matsubara T, Nakamura T, Uchida A, Sudo A
  • Organizer: 9TH ASIS PACIFIC MUSCULOSKELETAL TUMOR SOCIETY MEETING 2012 Connectine Tissue Oncology Society
  • Place of Presentation: Czech Republic, Prague
• [Presentation] A Minimally Invasive Surgery for Bone Metastases Using the Combination of Photodynamic Therapy and Hyperthermia Treatment (2012)
  • Author(s): Matsubara T, Kusuzaki K, Matsumine A, Asanuma K, Nakamura T, Uchida A, Sudo A
  • Organizer: 9TH ASIS PACIFIC MUSCULOSKELETAL TUMOR SOCIETY MEETING 2012 Connectine Tissue Oncology Society
  • Place of Presentation: Czech Republic, Prague
• [Presentation] Tissue Factor Mrna Expression in 68 Soft Tissue Sarcoma Patients (2012)
  • Author(s): Asanuma K, Matsumine A, Matsubara T, Atsumi S, Matsui Y, Nakamura T, Uchida A, Sudo A
  • Organizer: Combined 33rd SICOT & 17th PAOA Orthopaedic World Conference
  • Place of Presentation: Dubai, United Arab Emirates
• [Presentation] Analysis of tumor metastatic factor using low coagulation activity model in mice (2012)
  • Author(s): Asanuma K, Matsumine A, Asanuma Y, Akita N, Yoshikawa T, Yoshida K, Matsubara T, Nakamura T, Okamoto T, Hayashi T, Uchida A, Sudo A
  • Organizer: 13) Orthopaedic Research Society
  • Place of Presentation: San Francisco, USA
• [Presentation] A Novel Oncolytic Virotherapy Using Live-attenuated Poliovirus for Soft Tissue Sarcoma (2012)
  • Author(s): Atsumi S, Matsumine A, Nakamura T, Niini R, Matsubara T, Asanuma K, Uchida A, Sudo A
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: San Francisco, USA
• [Presentation] Acridine Orange Inhibits Pulmonary Metastasis and Invasion on Mouse Oseteosarcoma (2012)
  • Author(s): Satanaka H, Akeda K, Kusuzaki K, Tujii M, Iino T, Uemura T, Nakamura T, Matsubara T, Asanuma K, Matsumine A, Sudo A
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: San Francisco, USA
• [Presentation] Oncolytic virotherapy for human bone and soft tissue sarcomas using live-attenuated poliovirus (2012)
  • Author(s): Matsumine A
  • Organizer: 9TH ASIS PACIFIC MUSCULOSKELETAL TUMOR SOCIETY MEETING 2012
  • Place of Presentation: Kuala Lumpur
• [Presentation] 弱毒ポリオ生ワクチンによる骨･軟部肉腫に対する抗腫瘍効果の機序の検討 (2012)
  • Author(s): 渥美 覚、松峯昭彦、新美 塁、中村知樹、松原孝夫、淺沼邦洋、豊田秀実、駒田美弘、内田淳正、須藤啓広
  • Organizer: 第45回日本整形外科学会骨･軟部腫瘍学術集会
  • Place of Presentation: 東京都
• [Presentation] 弱毒ポリオ生ワクチンを用いた悪性骨軟部腫瘍に対する腫瘍融解療法 (2012)
  • Author(s): 松峯昭彦、渥美覚、新美塁、中村知樹、松原孝夫、淺沼邦洋、飯野隆大、豊田秀実、駒田美弘、内田淳正、須藤啓広
  • Organizer: 第71回日本癌学会学術総会
  • Place of Presentation: 札幌市
• [Presentation] 弱毒ポリオ生ワクチンを用いた悪性･骨軟部腫瘍に対する腫瘍融解療法 (2012)
  • Author(s): 松峯昭彦、渥美覚、新美塁、中村知樹、松原孝夫、淺沼邦洋、飯野隆大、豊田秀実、駒田美弘、内田淳正、須藤啓広
  • Organizer: 第27回日本整形外科学会基礎学術集会
  • Place of Presentation: 名古屋市
• [Presentation] A Novel Oncolytic Virotherapy Using Live-attenuated Poliovirus for Soft Tissue Sarcoma. (2012)
  • Author(s): S. Atsumi, A. Matsumine, Y. Asanuma, N. Akita, T. Yoshikawa, K. Yoshida, T. Matsubara, T. Nakamura, T. Okamoto, T. Hayashi, A. Uchida, A. Sudo.
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: California
• [Presentation] Analysis of tumor metastatic using low coagulation activity model in mice. (2012)
  • Author(s): K. Asanuma, A. Matsumine, Y. Asanuma, N. Akita, T. Yoshikawa, K. Yoshida, T. Matsubara, T. Nakamura, T. Okamoto, Tatsuya Hayashi, A. Uchida, A. Sudo.
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: California
• [Presentation] Acridine Orange Inhibits Pulmonary Metastasis and Invasion on Mouse Oseteosarcoma. (2012)
  • Author(s): H. Satanaka, K. Akeda, K. Kusuzaki, M. Tujii, T. Iino, T. Uemura, T. Nakamura, T. Matsubara, K. Asanuma, A. Matsumine, A. Sudo.
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: California
• [Presentation] Infliximab suppresses the lung metastasis in osteosarcoma cell line. (2012)
  • Author(s): H. Kato, H. Wakabayashi, A. Matsumine, A. Sudo.
  • Organizer: Orthopaedic Research Society
  • Place of Presentation: California
• [Presentation] The inhibition of lung metastasis by inactivation of coagulation activity may lead to dissemination of tumor cells. (2011)
  • Author(s): K. Asanuma, A. Matsumine, Y. Asanuma, T. Yoshikawa, K. Yoshida, T. Matsubara, T. Nakamura, A. Uchida, A. Sudo.
  • Organizer: EUROPEAN ORTHOPAEDIC RESEACH SOCIETY
  • Place of Presentation: Austria
• [Presentation] 軟部肉腫における診断の遅延が臨床経過に及ぼす影響. (2011)
  • Author(s): 中村知樹、松峯昭彦、松原孝夫、淺沼邦洋、渥美覚、内田淳正、須藤啓広.
  • Organizer: 第44回日本整形外科学会骨･軟部腫瘍学術集会
  • Place of Presentation: 京都市
• [Presentation] 低悪性度軟骨肉腫の治療成績. (2011)
  • Author(s): 渥美覚、松峯昭彦、淺沼邦洋、松原孝夫、中村知樹、内田淳正、須藤啓広.
  • Organizer: 第44回日本整形外科学会骨･軟部腫瘍学術集会
  • Place of Presentation: 京都市
• [Presentation] 下肢骨･軟部腫瘍術後の深部静脈血栓症の発生率と危険因子について. (2011)
  • Author(s): 山口敏郎、松峯昭彦、施徳全、新美塁、中村知樹、松原孝夫、淺沼邦洋、長谷川正裕、須藤啓広.
  • Organizer: 第44回日本整形外科学会骨･軟部腫瘍学術集会
  • Place of Presentation: 京都市
• [Presentation] アクリジンオレンジを用いた分子イメージングの低侵襲外科手術への応用. (2011)
  • Author(s): 楠崎克之、松原孝夫、里中東彦、中村知樹、松峯昭彦、須藤啓広、内田淳正.
  • Organizer: 第44回日本整形外科学会骨･軟部腫瘍学術集会
  • Place of Presentation: 京都市
• [Presentation] 京セラ腫瘍用人工膝関節:PHK IIIの治療成績に関する追加調査報告 ―骨軟部肉腫治療研究会(JMOG)による多施設共同研究― (2011)
  • Author(s): 松峯昭彦、上田孝文、杉田孝、矢澤康男、井須和男、平賀博明、川井章、阿部哲士、薬師寺俊剛、淺沼邦洋、松原孝夫、中村知樹、内田淳正、須藤啓広.
  • Organizer: 第44回日本整形外科学会骨･軟部腫瘍学術集会
  • Place of Presentation: 京都市
• [Presentation] 悪性骨･軟部腫瘍切除後の骨欠損に対する術中処理自家骨移植法の治療成績. (2011)
  • Author(s): 松原孝夫、松峯昭彦、楠崎克之、中村知樹、淺沼邦洋、渥美覚、内田淳正、須藤啓広.
  • Organizer: 第44回日本整形外科学会骨･軟部腫瘍学術集会
  • Place of Presentation: 京都市
• [Presentation] マグネタイト含有リン酸カルシウム骨ペーストを用いた難治性骨腫瘍に対する温熱療法. (2011)
  • Author(s): 松峯昭彦、淺沼邦洋、松原孝夫、中村知樹、渥美覚、内田淳正、須藤啓広.
  • Organizer: 日本ハイパーサミーア学会 第28回大会
  • Place of Presentation: 名古屋市
• [Presentation] 体外交流電磁場発生装置を用いた転移性骨腫瘍に対する電磁性体温熱療法. (2011)
  • Author(s): 松峯昭彦、中村知樹、松原孝夫、淺沼邦洋、内田淳正、須藤啓広.
  • Organizer: 日本ハイパーサミーア学会 第28回大会
  • Place of Presentation: 名古屋市
• [Presentation] Ewing肉腫における新規腫瘍マーカーの探索:ADAMTS4発現の診断的意義の解析. (2011)
  • Author(s): 美濃部こころ、松峯昭彦、小埜良一、飯野隆大、林泰秀、北村俊雄、内田淳正、須藤啓広、野板哲哉.
  • Organizer: 第26回日本整形外科学会基礎学術集会
  • Place of Presentation: 前橋市
• [Presentation] 血液凝固抑制マウスを用いた肺転移関連因子の解析 (2011)
  • Author(s): 淺沼邦洋、松峯昭彦、松原孝夫、中村知樹、吉川智朗、淺沼由美子、内田淳正、林辰弥、秋田展幸、岡本貴之、須藤啓広.
  • Organizer: 第26回日本整形外科学会基礎学術集会
  • Place of Presentation: 前橋市
• [Presentation] Dupuytren拘縮に対するアクリジンオレンジ光線力学的療法の殺細胞効果. (2011)
  • Author(s): 里中東彦、辻井雅也、飯田竜、堀和一郎、植村剛、長谷川正裕、飯野隆大、松峯昭彦、楠崎克之、須藤啓広.
  • Organizer: 第26回日本整形外科学会基礎学術集会
  • Place of Presentation: 前橋市
• [Presentation] 軟骨細胞分化にはN-カドヘリンの切断が必須である. (2011)
  • Author(s): 中空繁登、松峯昭彦、飯野隆大、若林徹、長谷川正裕、内田淳正、須藤啓広.
  • Organizer: 第26回日本整形外科学会基礎学術集会
  • Place of Presentation: 前橋市
• [Presentation] 高齢者の要介護認定に対する変形性膝関節症と骨粗鬆症の影響―旧宮川村検診より― (2011)
  • Author(s): 西村明展、松峯昭彦、長谷川正裕、若林弘樹、明田浩司、淺沼邦洋、辻井雅也、里中東彦、松原孝夫、中村知樹、山田知美、加藤公、内田淳正、須藤啓広.
  • Organizer: 第26回日本整形外科学会基礎学術集会
  • Place of Presentation: 前橋市
• [Presentation] 弱毒ポリオ生ワクチンによる悪性骨･軟部腫瘍の新しい腫瘍融解療法. (2011)
  • Author(s): 渥美覚、松峯昭彦、新美塁、中村知樹、松原孝夫、淺沼邦洋、豊田秀美、駒田美弘、内田淳正、須藤啓広.
  • Organizer: 第26回日本整形外科学会基礎学術集会
  • Place of Presentation: 前橋市
• [Presentation] 下腿遠位部悪性骨腫瘍に対する処理骨を用いた患肢温存の治療成績. (2011)
  • Author(s): 松井佑梨世、中村知樹、松原孝夫、淺沼邦洋、松峯昭彦、須藤啓広.
  • Organizer: 第117回中部日本整形外科災害外科学会･学術集会
  • Place of Presentation: 宇部市
• [Presentation] 大腿骨近位部の悪性骨軟部腫瘍に対する腫瘍用人工関節の治療成績. (2011)
  • Author(s): 淺沼邦洋、松峯昭彦、松原孝夫、中村知樹、内田淳正、須藤啓広.
  • Organizer: 第117回中部日本整形外科災害外科学会･学術集会
  • Place of Presentation: 宇部市
• [Presentation] 抗菌薬充填ハイドロキシアパタイトと有茎皮弁による脛骨慢性骨髄炎の治療. (2011)
  • Author(s): 辻井雅也、里中東彦、植村剛、松岡宏明、松峯昭彦、須藤啓広.
  • Organizer: 第117回中部日本整形外科災害外科学会･学術集会
  • Place of Presentation: 宇部市
• [Presentation] 血腫と診断された腫瘤の臨床および画像所見的特徴. (2011)
  • Author(s): 渥美覚、松峯昭彦、中村知樹、松原孝夫、淺沼邦洋、須藤啓広.
  • Organizer: 第117回中部日本整形外科災害外科学会･学術集会
  • Place of Presentation: 宇部市
• [Presentation] 膝蓋靱帯･アキレス腱周囲に発生した悪性軟部腫瘍手術における術中自家腱処理法. (2011)
  • Author(s): 松原孝夫、松峯昭彦、淺沼邦洋、中村知樹、渥美覚、須藤啓広.
  • Organizer: 第117回中部日本整形外科災害外科学会･学術集会
  • Place of Presentation: 宇部市
• [Presentation] 血管柄付き骨移植術を用いた上肢再建の経験. (2011)
  • Author(s): 辻井雅也、平田仁、里中東彦、植村剛、吉川智朗、海野宏至、石黒茂夫、飯田竜、中村知樹、松峯昭彦、須藤啓広.
  • Organizer: 第38回日本マイクロサージャリー学会学術集会
  • Place of Presentation: 新潟市
• [Presentation] 示指動静脈奇形に対して爪を含めたhemipulp flapにて再建した1例. (2011)
  • Author(s): 海野宏至、辻井雅也、森田哲正、植村剛、里中東彦、松峯昭彦、須藤啓広.
  • Organizer: 第38回日本マイクロサージャリー学会学術集会
  • Place of Presentation: 新潟市
• [Presentation] 軸椎に発生した原発性平滑筋肉腫の1例. (2011)
  • Author(s): 山田淳一、明田浩司、松峯昭彦、須藤啓広、榊原紀彦、笠井裕一、藤井渉、福島達樹.
  • Organizer: 第76回東海脊椎脊髄病研究会学術集会
  • Place of Presentation: 名古屋市
• [Book] 先端医療シリーズ44、臨床医のための最新整形外科、軟部肉腫に対するアクリジンオレンジ療法 (2013)
  • Author(s): 松峯昭彦、松原孝夫、楠崎克之
  • Total Pages: 570
  • Publisher: 先端医療技術研究所
• [Book] がん骨転移のバイオロジーとマネージメント、Part iiがん骨転移のマネージメント、疫学～骨関連事象、予後など～ (2012)
  • Author(s): 湏藤啓広、松峯昭彦
  • Total Pages: 400
  • Publisher: 医薬ジャーナル
• [Book] Chapter VI : New concept of limb salvage surgery in musculoskeletal sarcomas with acridine orange therapy (2012)
  • Author(s): Kusuzaki K, Hosogi S, Ashihara E, Matsubara T, Satonaka H, Nakamura T, Matsumine A, Sudo A, Uchida A, Murata H, Baldini N, Fais S, Marunaka Y
  • Total Pages: 179
  • Publisher: Nova Science Publishers
• [Book] 整形外科臨床パサージュ6、軟部腫瘍プラクティカルガイド、軟部腫瘍における生検の実際 (2011)
  • Author(s): 松峯昭彦
  • Total Pages: 240
  • Publisher: 中山書店
• [Book] 薬局増刊号、病気と薬パーフェクトBOOK,骨肉腫 (2011)
  • Author(s): 松原孝夫、松峯昭彦、須藤啓広
  • Total Pages: 1928
  • Publisher: 南山堂