| Project/Area Number |
23592360
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YOKOYAMA Osamu 福井大学, 医学部, 教授 (90242552)
KUSAKA Yukinori 福井大学, 医学部, 教授 (70135680)
MATSUTA Yosuke 福井大学, 医学部, 助教 (90345687)
TSUCHIYAMA Katsuki 福井大学, 医学部附属病院, 助教 (90464073)
MATSUMOTO Chieko 福井大学, 教育地域科学部, 准教授 (80377043)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 夜間頻尿 / 高血圧 / 肥満 / 糖尿病 / 脂質異常 / 高血糖 / 脂質代謝異常 |
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| Research Abstract |
We hypothesized that nocturia may be associated with the incidence of MetS and conducted a 4-year longitudinal study that investigated the possible association. We collected data on 5,701 individuals who participated in a multiphasic health screening in Fukui, Japan, in 2003 (baseline) and 2007, and were 65 years and less at baseline. After excluding participants with MetS at baseline, data from 5,234 participants were subjected to analysis. The participants' mean age was 55.6 years at baseline. A total of 210 participants (4%) developed MetS during the four-year study period. After adjusting for age and gender, a significant association was observed between the incidence of MetS and nocturia (experienced "sometimes" or "always"). For the incidence of MetS, the multivariate odds ratios (95% CI) of "sometimes" and "always" nocturia were 2.3 (1.1-4.7) and 2.9 (1.1-7.9), respectively. The results of our epidemiological study indicate that nocturia can be a precursor of MetS.
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