Protection of ischemia-reperfusion injury in intestinal transplantation by EGF and ischemia preconditioning(IPC)
| Project/Area Number |
23592635
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatric surgery
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| Research Institution | Kansai Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAIBORI Masaki 関西医科大学, 医学部, 准教授 (30333199)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 虚血再灌流障害 / 小腸移植 / EGF / ischemic preconditioning / 虚血再還流障害 / Ischemic preconditioning / ＥＧＦ |
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| Research Abstract |
Creation of rat model of isogeneic intestinal transplantation with ischemic preconditioning(IPC) failed, thus we performed another experiment that clamp of first branch of the superior mesenteric artery for 10 minutes followed by reperfusion of the artery for 30 minutes as an alternative method for IPC. In this alternative experimental methods, adequate timing or administration route of EGF were examined but no reliable stable data were not obtained so far.
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Report
(4 results)
Research Products
(72 results)
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[Journal Article] Extrahepatic bile duct measurement by using transabdominal ultrasound in Japanese adults : multi-center prospective study2013
Author(s)
Itoi T, Kamisawa T, Fujii H, Inui K, Maguchi H, Hamada Y, Nakano T, Ando H, Koshinaga T, Shibagaki K, Obayashi T, Miyazawa Y
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Journal Title
J Gastroenterol
Volume: 48
Pages: 1045-1050
NAID
Related Report
Peer Reviewed
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