| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
Mineral Trioxide Aggregate (MTA) has been in widespread use as endodontic cements. However, MTA has disadvantages: it does not have good handling property, and the setting time is relatively long. The aim of this study is to develope new endodontic cements.
Calcium phosphate cements (CPCs) has been improved for good handling property and short setting time; Premixed CPC and Fluorapatite forming CPC. Mineralizing ability in osteoblasts and rat subcutaneous tissue response of CPCs were evaluated when compared to MTA. These CPCs indicated the same cell proliferation, alkaline phosphatase activity, mineralized nodule formation, and calcium contents in nodules as those of MTA. Theese results suggest that these CPCs has the possibility of novel endodontic cement.
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