| Project/Area Number |
23650150
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | Tohoku University (2012)
The University of Tokyo (2011) |
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Principal Investigator |
NAGASAKI Masao 東北大学, 東北メディカル・メガバンク機構, 教授 (90396862)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 次世代シーケンサ / 次世代シークエンサ / トランスクリプトーム / RNA-Seq / lincRNA / ベイズ法 / スーパーコンピュータ / 高性能シークエンサ / 数理統計モデル |
|---|
| Research Abstract |
High performance sequencer (Hit-Seq) generates massive amounts of short reads. Hit-Seq is used for the analysis of transcriptome expressions. Especially, it is important to detect fusion transcripts and isoforms expression from overlapped region in a chromosome. This research developed a new method to detect isoform expressions from RNA-Seq data. By applying this method on supercomputer environment, more accurate expressions to unkown lincRNAs and mRNAs from thousands RNA-Seq data can be inferred.
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