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Development of the microcirculation functional measuring method by pressurization optical sensing

Research Project

Project/Area Number 23650301
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical systems
Research InstitutionGunma University

Principal Investigator

YAMAKOSHI Yoshiki  群馬大学, 大学院・工学研究科, 教授 (10174640)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords生体光センシング / ランバートベアー則 / 末梢血管 / 血流依存性 / 微小循環 / 生体光計測 / 血流依存性血管拡張反応 / プレスチモグラフ / 加圧光センサ / 加圧光センサ法
Research Abstract

In order to measure the amount of blood of microcirculation in papillary layer of skin, a optical sensing with pressurization mechanism was proposed. As an application of the proposed method, the change of blood amount by flow mediated dilatation was measured. A parameter of pulsation origin of the arteriole obtained by this technique showed goodcorrelation with the conventional method. However, parameters about microcirculation indicated inherent responses which are different from the conventional method. This result shows a possibility that novel information about microcirculation will be acquired by the proposing method.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (6 results)

All 2013 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (4 results)

  • [Journal Article] Characterization of skin dermis microcirculation in flow-mediated dilation using optical sensor with pressurization mechanism2013

    • Author(s)
      Yamakoshi Y, Kotani K, Taniguchi N, Miwa T.
    • Journal Title

      Med Biol Eng Comput

      Volume: 51(5) Pages: 497-505

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of skin dermis microcirculation in flow-mediated dilation using optical sensor with pressurization mechanism2013

    • Author(s)
      Y. Yamakoshi, K. Kotani, N. Taniguchi and T. Miwa
    • Journal Title

      Med. Biol. Eng. Comput

      Volume: 51 Issue: 5 Pages: 497-505

    • DOI

      10.1007/s11517-012-1017-2

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 微小循環の評価を目的とした加圧光センサ法の提案2011

    • Author(s)
      中路祥彰,森村隆志,高橋直弘,山越芳樹
    • Organizer
      生体医工学シンポジューム2011
    • Place of Presentation
      長野
    • Year and Date
      2011-09-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 加圧光センサによる上腕部駆血解除前後の微小循環評価2011

    • Author(s)
      森村隆志,中路祥彰,高橋直弘,山越芳樹
    • Organizer
      生体医工学シンポジューム2011
    • Place of Presentation
      長野
    • Year and Date
      2011-09-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 微小循環の評価を目的とした加圧光センサ法の提案2011

    • Author(s)
      中路祥彰, 森村隆志, 高橋直弘, 山越芳樹
    • Organizer
      生体医工学シンポジウム2011
    • Place of Presentation
      長野
    • Related Report
      2011 Research-status Report
  • [Presentation] 加圧光センサによる上腕部駆血解除前後の微小循環評価2011

    • Author(s)
      森村隆志, 中路祥彰, 高橋直弘, 山越芳樹
    • Organizer
      生体医工学シンポジウム2011
    • Place of Presentation
      長野
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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