Development of contact less brain wave monitoring device using highly sensitiveMI sensor and its application for medical diagnosis

• Project/Area Number: 23650306
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Medical systems
• Research Institution: Nagoya University
• Principal Investigator: UCHIYAMA Tsuyoshi 名古屋大学, 工学研究科, 准教授 (00203555)
• Co-Investigator(Kenkyū-buntansha): NAKAYAMA Shinsuke 名古屋大学, 医学研究科, 准教授 (30192230)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 脳波 / 磁気センサ / 細胞組織

Research Abstract

We have developed a gradiometer based on highly sensitive magnetoimpedance (MI) sensor aiming for non-contact brain wave measurement. The measurement results of magnetic field at the back of head support that the developed prototype sensor system is useful for non-contact brain wave measurement or magnetoencephalography measurement without magnetic shielding. We investigated relation between electrical activity and magnetic activity in a smooth muscle tissue isolated from guinea pig.

Research Products

• [Journal Article] Human Biomagnetic Field Measurement Using Pico-Tesla Sentive Amorphous Wire Magentoimcedance Sensor (2013)
  • Author(s): T. Uchiyama , K. Mohri, S. Nakayama
  • Journal Title: Sensor Letter Volume: 11 Pages: 191-194
  • Peer Reviewed
• [Journal Article] MI素子を利用した高精度グラジオメータによる摘出細胞組織の活動計測 (2013)
  • Author(s): 内山 剛
  • Journal Title: 電気学会ﾏｸﾞﾈﾃｨｯｸｽ研究会資料 Volume: MAG-13-12 Pages: 49-54
• [Journal Article] Recent Advances of Pico-Tesla Resolution Magneto-Impedance Sensor Based on Amorphous Wire CMOS IC MI Sensor (2012)
  • Author(s): T. Uchiyama , K. Mohri, Y. Honkura, L. Panina
  • Journal Title: IEEE Trans.Magn Volume: 48 Pages: 3833-3889
  • Peer Reviewed
• [Journal Article] Physiological Magnetic Stimulation for Arousal of Elderly Car Driver Evaluated With Electro-Encephalogram and Spine Magnetic Field (2012)
  • Author(s): K. Mohri, T. Uchiyama , M. Yamada, Y. Mohri, K. Endo, T. Suzuki, Y. Inden
  • Journal Title: IEEE Trans.Magn Volume: 48 Pages: 3505-3508
  • Peer Reviewed
• [Journal Article] Super MI Sensor: Recent Advances of Amorphous Wire and CMOS-IC Magneto-Impedance Sensor (2012)
  • Author(s): K. Mohri , Y. Honkura,L Panina , T. Uchiyama
  • Journal Title: J. Nonosci Nonotecnol Volume: 12 Pages: 7491-7495
  • Peer Reviewed
• [Journal Article] MI素子による高性能グラジオメーターの開発と細胞組織活動計測への応用 (2012)
  • Author(s): 内山 剛, 中山 晋介,熱田 論志
  • Journal Title: 電気学会研究会資料 MAG-12-019
  • NAID: 10030328483
• [Journal Article] Recent Advances of Pico-Tesla Resolution Mangeto-impedance Sensor Based on Amorphous Wire CMOS IC MI Sensor (2012)
  • Author(s): T.Uchiyama
  • Journal Title: IEEE. Trans. Magn Volume: 48 Pages: 3833-3839
  • Peer Reviewed
• [Journal Article] Physiological Magnetic Stimulation for Arousal Elderly Car Driver Evaluation with Electro-Encephalogram and Spine Magnetic Field (2012)
  • Author(s): K. Mohri
  • Journal Title: IEEE. Trans. Magn Volume: 48 Pages: 3503-3508
  • Peer Reviewed
• [Journal Article] 医療技術における磁気応用研究の動向ー生体機能計測に於ける磁気応用技術ー (2012)
  • Author(s): 伊良皆啓二
  • Journal Title: 電気学会マグネティックスリニアドライブ合同研究会資料 Volume: MAG-12-13 Pages: 5-12
• [Journal Article] MI素子による高性能グラジオメーターの開発と細胞組織計測への応用 (2012)
  • Author(s): 内山 剛
  • Journal Title: 電気学会マグネティックスリニアドライブ合同研究会資料 Volume: MAG-12-19 Pages: 43-47
• [Journal Article] 医療技術における磁気応用研究の動向ー生体機能計測における磁気応用技術ー (2012)
  • Author(s): 伊良皆啓治、上原弦、内山剛、円福敬二
  • Journal Title: 電気学会マグネティックス研究会 Volume: MAG-12-13 Pages: 5-10
• [Journal Article] On the state-of-the-art in magnetic microwires and expected trends for scientific and technological studies (2011)
  • Author(s): M.Va´zquez, H. Chiriac, A. Zhukov, L. Panina, T. Uchiyama
  • Journal Title: Phys. Stat. Solid Volume: 208 Pages: 493-501
  • Peer Reviewed
• [Journal Article] Arousal Effect of Physiological Magnetic Stimulation on Elder Person's Spine for Prevention of Drowsiness During Car Driving (2011)
  • Author(s): K. Mohri, T. Uchiyama, M. Yamada, T. Watanabe, Y. Inden, T. Kato, S. Iwata
  • Journal Title: IEEE Trans. Magn Volume: 47 Pages: 3066-3069
  • Peer Reviewed
• [Journal Article] Measurement of spontaneous oscillatory magnetic field of guinea-pig stomach muscle preparation using pico-Tesla resolution amorphous wire magneto-impedance sensor (2011)
  • Author(s): T. Uchiyama, K. Mohri, S. Nakayama
  • Journal Title: IEEE Trans. Magn Volume: 47 Pages: 3070-3073
  • Peer Reviewed
• [Journal Article] Pulse-Driven Magnetoimpedance Sensor Detection of Cardiac Magnetic Activity (2011)
  • Author(s): S. Nakayama, K. Sawamura, K. Mohri, T. Uchiyama
  • Journal Title: PLoS ONE Volume: 16
  • Peer Reviewed
• [Journal Article] Pulse-driven magnetoimpedance sensor detection of biomagnetic fields in musculatures with spontaneous electric activity (2011)
  • Author(s): S. Nakayama, S. Atsuta, T. Shinmi, T. Uchiyama
  • Journal Title: Biosensors and Bioelectronics Volume: 27 Pages: 34-39
  • Peer Reviewed
• [Journal Article] On the state-of-the-art in magnetic micro wires and expected trends for scientific and technological studies (2011)
  • Author(s): Va´zquez M, Chiriac H, Zhukov A, Panina L, Uchiyama T
  • Journal Title: Phys. Stat. Solid. A Volume: 208 Pages: 493-501
  • Peer Reviewed
• [Journal Article] Arousal Effect of Physiological Magnetic Stimulation on Elder Person's Spine for Prevention of Drowsiness During Car Driving (2011)
  • Author(s): Mohri K, Uchiyama T, Yamada M, Watanabe T, Inden Y, Kato T, Iwata S
  • Journal Title: IEEE Trans. Magn. Volume: 47 Pages: 3066-3069
  • Peer Reviewed
• [Journal Article] Measurement of spontaneous oscillatory magnetic field of guinea-pig stomach muscle preparation using pico-Tesla resolution amorphous wire magneto-impedance sensor (2011)
  • Author(s): Uchiyama T, Mohri K, Nakayama S
  • Journal Title: IEEE Trans. Magn. Volume: 47 Pages: 3070-3073
  • Peer Reviewed
• [Journal Article] Pulse-Driven Magneto impedance Sensor Detection of Cardiac Magnetic Activity (2011)
  • Author(s): Nakayama S, Sawamura K, Mohri K, Uchiyama T
  • Journal Title: PLoS ONE Volume: 6
  • Peer Reviewed
• [Journal Article] Pulse-driven magneto impedance sensor detection of biomagnetic fields in musculatures with spontaneous electric activity (2011)
  • Author(s): Nakayama S, Atsuta S, Shinmi T, Uchiyama T
  • Journal Title: Biosensors and Bioelectronics Volume: 27 Pages: 34-39
  • Peer Reviewed
• [Presentation] 高感度 MI センサ回路の小型化に関する研究 (2013)
  • Author(s): 奥田有記浩,内山 剛,田島真吾
  • Organizer: 電気学会全国大会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2013-03-22
• [Presentation] パルス駆動型 MI センサのコイル検出電圧モデルの検討 (2013)
  • Author(s): 山田斉哉,内山 剛,河原真二,山本峻也
  • Organizer: 電気学会全国大会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2013-03-22
• [Presentation] 高感度 MI センサを用いた脳波計測の基礎検討 (2013)
  • Author(s): 藤波駿一朗,田島真吾,田中綾子,内山剛
  • Organizer: 電気学会全国大会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2013-03-22
• [Presentation] MI センサを利用した簡易型スマートトラフィックカウンタによる車両通行計測 (2013)
  • Author(s): 梶浦恭裕,後藤宏明,今川由加, 内山 剛
  • Organizer: 電気学会全国大会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2013-03-22
• [Presentation] MI 素子を利用した高精度グラジオメーターによる摘出細胞組織の活動磁気計測 (2013)
  • Author(s): 内山 剛,中山晋介
  • Organizer: 電気学会マグネティクス研究会
  • Place of Presentation: 電力研究所
  • Year and Date: 2013-02-28
• [Presentation] Multi Amorphous Wire Assembly GMI Sensor for Stable pico-Tesla Resolution (2013)
  • Author(s): T. Uchiyama , N. Hamada , C.M. Cai
  • Organizer: 12th Joint MMM/INTERMAG Conference
  • Place of Presentation: Chicago, USA
  • Year and Date: 2013-01-18
• [Presentation] Development of built-in multifunctional traffic counter using MI sensor located roadside (2013)
  • Author(s): H. Gotho, T. Uchiyama
  • Organizer: 12th Joint MMM/INTERMAG Conference
  • Place of Presentation: Chicago, USA
  • Year and Date: 2013-01-18
• [Presentation] Highly sensitive amorphouse wire CMOS magneto-impedance sensor with coplanar line filter for avoiding interference noise (2013)
  • Author(s): S. Kawahara, T. Uchiyama, S.Yamamoto
  • Organizer: 12thJoint MMM/INTERMAG Conference
  • Place of Presentation: Chicago, USA
  • Year and Date: 2013-01-18
• [Presentation] Highly sensitive amorphous wire CMOS magneto-impedance sensor with coplanar line filter for avoiding interference nose (2013)
  • Author(s): S.Kawahara
  • Organizer: 12th Joint MMM Intermag Conference
  • Place of Presentation: Chikago, USA
• [Presentation] Multi Amorphous Wire assembly GMI Sensor for Stable pico-Tesla Resolution (2013)
  • Author(s): T.Uchiyama
  • Organizer: 12th Joint MMM Intermag Conference
  • Place of Presentation: Chikago, USA
• [Presentation] Make biomagnetic field realistic: Application of pulse-driven magnetoimpedance sensor to physiology (2013)
  • Author(s): 中山晋介
  • Organizer: 日本生理学会大会
  • Place of Presentation: 東京
• [Presentation] A MEG measurement using pico-tesla resolution amorphous wire magneto-impedance sensor with Simultaneously recorded EEG (2012)
  • Author(s): S. Tajima, K. Oho, T. Uchiyama, K. Mohri, M. Yamada
  • Organizer: ICAUMS2012
  • Place of Presentation: Nara.
  • Year and Date: 2012-10-05
• [Presentation] MI センサを利用した道路脇設置型スマートトラフィックカウンタによる車両通行計測 (2012)
  • Author(s): 梶浦恭裕,後藤宏明,今川由加, 内山 剛
  • Organizer: 電気学会マグネティクス研究会
  • Place of Presentation: 電磁材料研究所,仙台
  • Year and Date: 2012-09-25
• [Presentation] アモルファスワイヤ MI 素子の高周波特性と磁気センサ応用 (2012)
  • Author(s): 山田斉哉,内山 剛,河原真二,山本峻也
  • Organizer: 電気学会マグネティクス研究会
  • Place of Presentation: 電磁材料研究所,仙台
  • Year and Date: 2012-09-25
• [Presentation] MI マイクロ磁気センサを用いた組み込み型多機能トラフィックカウンタの開発 (2012)
  • Author(s): 後藤宏明,梶浦恭裕,今川由加, 内山 剛
  • Organizer: 電気学会 A 部門大会
  • Place of Presentation: 秋田大学
  • Year and Date: 2012-09-21
• [Presentation] コプレーナラインフィルタを利用した高感度・広帯域なパルス駆動型 MI センサの開発 (2012)
  • Author(s): 河原真二, 内山 剛
  • Organizer: 電気学会A 部門大会
  • Place of Presentation: 秋田大学
  • Year and Date: 2012-09-21
• [Presentation] コルピッツ発振回路を利用した高感度 MI センサの開発 (2012)
  • Author(s): 山本峻也, 内山 剛
  • Organizer: 電気学会 A 部門大会
  • Place of Presentation: 秋田大学
  • Year and Date: 2012-09-21
• [Presentation] A MEG measurement using pico-Tesla Sensitivity amorphous wire magento-impedance sensor for brain activity evaluation (2012)
  • Author(s): T. Uchiyama , K. Mohri S. Nakayama
  • Organizer: Invited ,PIERS
  • Place of Presentation: Moscow.
  • Year and Date: 2012-08-23
• [Presentation] 磁気インピーダンスセンサーによる平滑筋細胞組織計測と最近の高精度化 (2012)
  • Author(s): 中山晋介,熱田諭志, 内山 剛
  • Organizer: 第54回日本平滑筋学会
  • Place of Presentation: 東京慈恵会医科大学
  • Year and Date: 2012-08-03
• [Presentation] Physiological Magnetic Stimulation for Arousal of Elder Car Driver Evaluated with Electro-encephalogram and Spine Magnetic Field (2012)
  • Author(s): K. Mohri, M. Yamada, K. Endo, T. Suzuki, Y. Mohr and T. Uchiyama
  • Organizer: Intermag DE-04
  • Place of Presentation: Vancouver.
  • Year and Date: 2012-05-11
• [Presentation] Recent Advances of pico-Tesla Resolution Micro Magnetic Sensors Based on Amorphous Wireand CMOS IC MI Sensor (2012)
  • Author(s): T. Uchiyama, K. Mohri, Y. Honkura, L>Panina
  • Organizer: Invited, Intermag2012
  • Place of Presentation: Vancouver.
  • Year and Date: 2012-05-11
• [Presentation] 2012,パルス駆動磁気インピーダンスセンサーによる筋層標本での生体磁気計測 (2012)
  • Author(s): 中山晋介,熱田諭志,内山 剛
  • Organizer: 第89回日本生理学会松
  • Place of Presentation: 本文化会館
  • Year and Date: 2012-03-30
• [Presentation] 磁気利用センシングシステムの現状と将来展望 (2012)
  • Author(s): 内山 剛
  • Organizer: 電気学会全国大会
  • Place of Presentation: 広島工業大学
  • Year and Date: 2012-03-23
• [Presentation] ドライバへの脊柱磁気刺激による覚醒効果の実験的検証 (2012)
  • Author(s): 坂井孝太,川澄未来子,中野倫明,山田宗男,毛利佳之,毛利佳年雄, 内山 剛
  • Organizer: DIA2012 in はこだて
  • Place of Presentation: はこだて大学
  • Year and Date: 2012-03-09
• [Presentation] Recent Advances of pico-Tesla Resolution Micro Magnetic Sensors Based on Amorphous Wire and CMOS IC MI sensor (2012)
  • Author(s): T.Uchiyama
  • Organizer: Intermag
  • Place of Presentation: Vaccouver, Canada
  • Invited
• [Presentation] A MEG measurement using pico-Tesla sensitivity amorphous wire magneto-impedance sensor for brain activity measurement (2012)
  • Author(s): T.Uchiyama
  • Organizer: PIERS
  • Place of Presentation: Moscow,Russia
  • Invited
• [Presentation] A MEG measurement using pico-Tesla sensitivity amorphous wire magneto-impedance sensor with simultaneously recorded EEG (2012)
  • Author(s): S.Tajima
  • Organizer: ICAUMS
  • Place of Presentation: 奈良
• [Presentation] 磁気インピーダンスセンサーによる平滑筋細胞組織計測と最近の高精度化 (2012)
  • Author(s): 中山晋介
  • Organizer: 日本平滑筋学会総会
  • Place of Presentation: 東京
• [Presentation] Mi素子による高性能グラジオメーターの開発と細胞組織活動計測への応用 (2012)
  • Author(s): 内山 剛，中山晋介，熱田諭志
  • Organizer: 電気学会会マグネティックス/リニアドライブ合同研究会
  • Place of Presentation: 金沢大学
• [Presentation] 磁気利用センシングシステムの現状と将来展望 (2012)
  • Author(s): 内山 剛
  • Organizer: 電気学会全国大会(招待講演)
  • Place of Presentation: 広島工業大学
• [Presentation] パルス駆動磁気インピーダンスセンサーによる筋層標本での生体磁気計測 (2012)
  • Author(s): 中山晋介，熱田諭志，内山 剛
  • Organizer: 第89回日本生理学会
  • Place of Presentation: 松本文化会館
• [Presentation] アモルファスワイヤ磁気インピーダンス素子を用いた高精度グラジオメータの開発と細胞組織機能評価への応用 (2011)
  • Author(s): 内山 剛, 中山晋介,熱田諭志
  • Organizer: 日本磁気学会,朱鷺メッセ
  • Place of Presentation: 新潟
  • Year and Date: 2011-09-28
• [Presentation] MI マイクロ磁気センサを用いた組み込み型多機能トラフィックカウンタの開発 (2011)
  • Author(s): 後藤宏明, 大宮祥吾, 今川由加, 内山 剛
  • Organizer: 電気学会マグネティックス研究会
  • Place of Presentation: 鳥羽
  • Year and Date: 2011-09-20
• [Presentation] パルス励起型磁気センサによる平滑筋組織発生磁気活動計測 (2011)
  • Author(s): 熱田諭志,新見孝夫,内山 剛,中山晋介
  • Organizer: 第53回日本平滑筋学会
  • Place of Presentation: 東京
  • Year and Date: 2011-08-04
• [Presentation] 道路脇設置可能な磁気式小型トラフィックカウンタの開発 (2011)
  • Author(s): 大宮祥吾,後藤宏明,今川由加, 内山 剛
  • Organizer: 電気学会センサ・マイクロマシン部門
  • Place of Presentation: 東京工業大学
  • Year and Date: 2011-07-01
• [Presentation] の非接触励磁型MI センサの開発 (2011)
  • Author(s): 川原彰悟,内山 剛
  • Organizer: 電気学会センサ・マイクロマシン部門
  • Place of Presentation: 東京工業大学
  • Year and Date: 2011-07-01
• [Presentation] Recent Advances of Amorphous Wire & CMOS IC Magneto-Impedance Sensor for Super MI Sensor (2011)
  • Author(s): K. Mohri, Y. Honkura, L. Panina, T. Uchiyama
  • Organizer: Invited
  • Place of Presentation: Ordizia, Spain
  • Year and Date: 2011-06-03
• [Presentation] Arousal Effect of Physiological Magnetic Stimulation on Elder Person's Spine for Prevention of Drowsiness During Car Driving Magnetic Field (2011)
  • Author(s): K. Mohri, T. Uchiyama, M. Yamada, T. Watanabe, Y. Inden, T. Kato, S. Iwata
  • Organizer: Intermag2011
  • Place of Presentation: Taipei.
  • Year and Date: 2011-04-29
• [Presentation] Measurement of spontaneous oscillatory magnetic field of guinea-pig stomachmuscle preparation using pico-Tesla resolution amorphous wire magneto-impedance sensorA (2011)
  • Author(s): T. Uchiyama, K. Mohri, S. Nakayama
  • Organizer: Intermag2011
  • Place of Presentation: Taipei.
  • Year and Date: 2011-04-29
• [Presentation] 非接触励磁型MIセンサの開発 (2011)
  • Author(s): 川原彰悟、内山 剛
  • Organizer: 電気学会センサ・マイクロマシン部門
  • Place of Presentation: 東京工業大学
• [Presentation] Recent Advances of Amorphous Wire & CMOS IC Magneto-Impedance Sensor for Super MI Sensor (2011)
  • Author(s): Mohri K, Honkura Y, L.V.Panina, Uchiyama T
  • Organizer: RTNSA 2011(招待講演)
  • Place of Presentation: Ordizia
• [Presentation] Measurement of spontaneous oscillatory magnetic field of guinea-pig stomachmuscle preparation using pico-Tesla resolution amorphous wire magneto-impedance sensor (2011)
  • Author(s): Uchiyama T, Mohri K, Nakayama S
  • Organizer: Intermag2011
  • Place of Presentation: Taipei
• [Presentation] Arousal Effect of Physiological Magnetic Stimulation on Elder Person's Spine for Prevention of Drowsiness During Car Driving (2011)
  • Author(s): Mohri K, Uchiyama T, Yamada M, Watanabe T, Inden Y, Kato T, Iwata S
  • Organizer: Intermag2011
  • Place of Presentation: Taipei
• [Presentation] パルス励起型磁気センサによる平滑筋組織発生磁気活動計測 (2011)
  • Author(s): 熱田諭志，新見孝夫，内山 剛，中山晋介
  • Organizer: 第５３回日本平滑筋学会
  • Place of Presentation: ゆうぽうと
• [Presentation] アモルファスワイヤ磁気インピーダンス素子を用いた高精度グラジオメータの開発と細胞組織機能評価への応用 (2011)
  • Author(s): 内山 剛，中山晋介，熱田諭志
  • Organizer: 日本磁気学会
  • Place of Presentation: 朱鷺メッセ
• [Remarks]
  • URL: http://www.nuee.nagoya-u.ac.jp/labs/uchiyamalab/index.html
• [Remarks] 名古屋大学 電子情報システム専攻 電子工学部分野 知能デバイスグループ
  • URL: http://www.nuee.nagoya-u.ac.jp/labs/uchiyamalab/
• [Remarks]
  • URL: http://www.nuee.nagoya-u.ac.jp/labs/uchiyamalab/