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Biological functions of male mice songs平成 25年 4月 25 日現在

Research Project

Project/Area Number 23657062
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Animal physiology/Animal behavior
Research InstitutionAzabu University

Principal Investigator

KIKUSUI Takefumi  麻布大学, 獣医学部, 教授 (90302596)

Co-Investigator(Kenkyū-buntansha) 茂木 一孝  麻布大学, 獣医学部, 准教授 (50347308)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords行動生理 / 求愛歌 / フェロモン / 性行動 / 繁殖効率 / 嗜好性 / マウス / GnRH / アンドロゲン
Research Abstract

In this study, we demonstrated that 1) we used the two-choice test to determine the song preference of female mice by assessing the time engaged in searching behavior towards played-back songs. We determined that female mice can discriminate among male song characteristics and that females innately prefer songs from strains that are different from their parents. 2) this preference was reversed by cross-fostering and disappeared by fatherless rearing conditions, indicating that the preference was learned or could be modified by social experience with their fathers. 3) this preference was controlled under estrogens. 4) there was a positive correlation between emission number of songs of males and giving birth of females in pairs. 5) the preference identified in this study was observed when females were exposed to soiled male bedding or the male mouse pheromone ESP1, which we previously reported enhanced female sexual receptivity (Nature 2010). This result suggests that cross-modal information processing from both acoustic and olfactory signals may influence mate preference in mice.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (24 results)

All 2012 2011 Other

All Journal Article (4 results) (of which Peer Reviewed: 3 results) Presentation (18 results) (of which Invited: 1 results) Remarks (2 results)

  • [Journal Article] A role for strain differences in waveforms of ultrasonic vocalizations during male-female interaction2011

    • Author(s)
      Sugimoto H., et al
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 7 Pages: 22093-22093

    • DOI

      10.1371/journal.pone.0022093

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cross fostering experiments suggest that mice songs are innate2011

    • Author(s)
      Kikusui T, Nakanishi K, Nakagawa R, Nagasawa M, Mogi K, Okanoya K
    • Journal Title

      PLoS One

      Volume: 9;6(3)

    • Related Report
      2012 Final Research Report
  • [Journal Article] Cross fostering experiments suggest that mice songs are innate2011

    • Author(s)
      Kikusui T, Nakanishi K, Nakagawa R, Nagasawa M, Mogi K, Okanoya K.
    • Journal Title

      PLoS One

      Volume: 6(3)

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] A role for strain differences in waveforms of ultrasonic vocalizations during male-female interaction2011

    • Author(s)
      Sugimoto H, Okabe S, Kato M, Koshida N, Shiroishi T, Mogi T, Kikusui T, Koide T.
    • Journal Title

      PLoS One

      Volume: 6(7)

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Little evidence showing song learningin mice - Sexual attractiveness of male love songs2012

    • Author(s)
      Takefumi Kikusui, Akari Asaba
    • Organizer
      Workshop for Mouse Ultrasonic Communication
    • Place of Presentation
      Pasteur Institute, Paris
    • Related Report
      2012 Final Research Report
  • [Presentation] オスマウス求愛歌がメスの性行動・神経内分泌・繁殖効率に及ぼす影響2012

    • Author(s)
      浅場明莉、岡部祥太、永澤美保、茂木一孝、菊水健史
    • Organizer
      第17回日本行動神経内分泌研究会関西セミナーハウス
    • Related Report
      2012 Final Research Report
  • [Presentation] 雄マウス求愛歌の生物学的意義の解明2012

    • Author(s)
      浅場明莉、岡部祥太、永澤美保、茂木一孝、菊水健史
    • Organizer
      第154回日本獣医学会岩手大学
    • Related Report
      2012 Final Research Report
  • [Presentation] Little evidence showing song learning in mice - Sexual attractiveness of male love songs2012

    • Author(s)
      Takefumi Kikusui, Akari Asaba
    • Organizer
      Workshop for Mouse Ultrasonic Communication
    • Place of Presentation
      Pasteur Institute, Paris
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 雄マウス求愛歌の生物学的意義の解明2012

    • Author(s)
      10. 浅場明莉、岡部祥太、永澤美保、茂木一孝、菊水健史
    • Organizer
      第154回日本獣医学会
    • Place of Presentation
      岩手大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] オスマウス求愛歌がメスの性行動・神経内分泌・繁殖効率に及ぼす影響2012

    • Author(s)
      浅場明莉、岡部祥太、永澤美保、茂木一孝、菊水健史
    • Organizer
      第17回日本行動神経内分泌研究会
    • Place of Presentation
      関西セミナーハウス
    • Related Report
      2012 Annual Research Report
  • [Presentation] 性シグナル伝達を司る神経回路の性差構築機構の解明2011

    • Author(s)
      菊水健史
    • Organizer
      新学術領域研究「性差機構の分子基盤」の第2回領域会議
    • Place of Presentation
      佐賀県唐津市
    • Year and Date
      2011-08-31
    • Related Report
      2012 Final Research Report
  • [Presentation] マウス求愛歌の生物学的意義と発声の性差の解明2011

    • Author(s)
      浅場明莉、永澤美保、茂木一孝、菊水健史
    • Organizer
      新学術領域研究「性差機構の分子基盤」の第2回領域会議
    • Place of Presentation
      佐賀県唐津市
    • Year and Date
      2011-08-31
    • Related Report
      2012 Final Research Report
  • [Presentation] メスマウスのオス求愛歌嗜好性と繁殖機能に関する研究2011

    • Author(s)
      浅場明莉、永澤美保、茂木一孝、菊水健史
    • Organizer
      新学術領域研究「性差機構の分子基盤」の第2回領域会議
    • Place of Presentation
      佐賀県唐津市
    • Year and Date
      2011-08-31
    • Related Report
      2012 Final Research Report
  • [Presentation] 小出剛マウス交配行動時の超音波発声の役割2011

    • Author(s)
      杉本大樹、菊水健史、城石俊彦
    • Organizer
      第58回実験動物学会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 雌マウスの雄マウス求愛歌に対する嗜好性には嗅覚刺激が必要である2011

    • Author(s)
      浅場明莉、永澤美保、茂木一孝、菊水健史
    • Organizer
      第15回行動神経内研究会・第15回鋤鼻研究会との合同大会
    • Place of Presentation
      八王子セミナーハウス
    • Related Report
      2012 Final Research Report
  • [Presentation] Social cues and neural mechanisms in mother-pup interactions2011

    • Author(s)
      Takefumi Kikusui
    • Organizer
      日本学術振興会中国NSFCとの2国間共同セミナー及 び FirstAsia-Pacific Conference on Integrative Behavioral Scienceの共催大会
    • Place of Presentation
      中国西安市
    • Related Report
      2012 Final Research Report
  • [Presentation] 雌マウスの雄マウス求愛歌に対する嗜好性は幼少期に獲得される2011

    • Author(s)
      浅場明莉、岡部祥太、永澤美保、茂木一孝、菊水健史
    • Organizer
      4学会合同大会「Animal2011」
    • Place of Presentation
      慶應義塾大学三田キャンパス
    • Related Report
      2012 Final Research Report
  • [Presentation] マウス求愛歌の行動学的解析(Ultrasound communication inmice)2011

    • Author(s)
      菊水健史、小出剛
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Vocal development under hetero-specific environment, Producing and Perceiving Complex Acoustic Signals: Songbirds and Mice as Model Systems2011

    • Author(s)
      Okanoya, K., Nakanishi, K., Takahasi, M., Nakagawa, R., Kikusui, T.
    • Organizer
      Howard Hughes Janelia Conference(招待講演)
    • Place of Presentation
      Chevy Chase, MD
    • Related Report
      2011 Research-status Report
  • [Presentation] マウス交配行動時の超音波発声の役割2011

    • Author(s)
      杉本大樹、菊水健史、城石俊彦、小出剛
    • Organizer
      第58回実験動物学会
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] Male song communication in mice2011

    • Author(s)
      Kikusui T.
    • Organizer
      First Asia-Pacific Conference on Integrative Behavioral Science(招待講演)
    • Place of Presentation
      Shaanxi Normal University
    • Related Report
      2011 Research-status Report
  • [Presentation] Ultrasound communication in mice2011

    • Author(s)
      Kikusui T.
    • Organizer
      第34回日本神経科学会(招待講演)
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2011 Research-status Report
  • [Remarks]

    • URL

      https://sites.google.com/a/carazabu.com/car/

    • Related Report
      2012 Final Research Report
  • [Remarks] 伴侶動物学研究室

    • URL

      https://sites.google.com/a/carazabu.com/car/

    • Related Report
      2012 Annual Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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