Origin of the polarity during mouse development
| Project/Area Number |
23657148
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Developmental biology
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 極性 / 着床前胚 / 転写 / エピジェネティクス / インプリンティング / 卵割 / 受精 |
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| Research Abstract |
It is thought that human and mouse embryos acquire the first polarity of body axes during early development. In this study, a new knowledge will be acquired during early mouse embryo development, and be showed the detail of the mechanism. As a results, I showedthat (1) Ac
(1) Activity of LFE were shown in some blastomeres of 4-16 cell stage embryos.
(2) LFE positive cells contributed to extra-embryonic tissues.
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Report
(3 results)
Research Products
(21 results)
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[Journal Article] Fluid flow and interlinked feedback loops establish left-right asymmetric decay of Cerl2 mRNA in the mouse embryo2012
Author(s)
Nakamura, T., Saito, D., Kawasumi, A., Shinohara, K., Asai, Y., Takaoka, K., Dong, F., Takamatsu, A., Belo, J.A., Mochizuki, A., and Hamada, H.
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Journal Title
Nat.Communic
Volume: 3
Issue: 1
Pages: 1322-1322
DOI
Related Report
Peer Reviewed
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