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A study on food component(s) enhancing zinc absorption for preventing zinc deficiency

Research Project

Project/Area Number 23658112
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Food science
Research InstitutionKyoto University

Principal Investigator

KAMBE Taiho  京都大学, 生命科学研究科, 准教授 (90303875)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords亜鉛欠乏 / 高齢者 / 亜鉛トランスポーター / ZIP4 / 大豆抽出物 / 消化管吸収 / 食品因子 / ソヤサポニン / 予防
Research Abstract

Zinc is an essential nutrient for human health. Recently, people with marginal zinc deficiency have been detected. Thus, strategies for increasing zinc absorption is important, because its efficiency is estimated to be about 30%. In the intestinal epithelial cells, zinc transporter ZIP4 functions as an essential molecule for zinc absorption. Exogenous expression of ZIP4 results in zinc uptake into the cells, suggesting that food factor(s) increasing ZIP4 expression should be a potential enhancer of zinc absorption. In this study, we screened for suitable food components with the ability to increase the abundance of this zinc transporter. Soybean extracts were identified and their effect was attributed to specifically decreased endocytosis of ZIP4 triggered by zinc, and soyasaponin was identified as an active component that increased both ZIP4 protein abundance and zinc levels from one extract. Our results suggest that soybean extracts may be useful to improve zinc absorption in humans.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (78 results)

All 2014 2013 2012 2011 Other

All Journal Article (31 results) (of which Peer Reviewed: 5 results) Presentation (47 results) (of which Invited: 6 results)

  • [Journal Article] Methods to Evaluate Zinc Transport into and out of the Secretory and Endosomal-Lysosomal Compartments in DT40 Cells2014

    • Author(s)
      Kambe T
    • Journal Title

      Methods Enzymol

      Volume: 534 Pages: 77-92

    • NAID

      120005359197

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] 「有害物質の膜輸送とトランスポーター」, 毒性の科学-分子・細胞から人間集団まで2014

    • Author(s)
      神戸大朋(熊谷嘉人, 姫野誠一郎, 渡辺知保 編)
    • Journal Title

      東京大学出版会

      Pages: 24-27

    • Related Report
      2013 Final Research Report
  • [Journal Article] 有害物質の膜輸送とトランスポーター2014

    • Author(s)
      神戸大朋
    • Journal Title

      毒性の科学-分子・細胞から人間集団まで

      Volume: なし Pages: 24-27

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Cooperative functions of ZnT1, metallothionein and ZnT4 in the cytoplasm are required for full activation of TNAP in the early secretory pathway2013

    • Author(s)
      Fujimoto S, Itsumura N, Tsuji T, Anan Y, Tsuji N, Ogra Y, Kimura T, Miyamae Y, Masuda S, Nagao M and Kambe T
    • Journal Title

      PLoS One

      Volume: 8

    • NAID

      120005343924

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] Identification of 6-octadecynoic acid from a methanol extract of Marrubium vulgare L. as a peroxisome proliferator-activated receptor γ agonist2013

    • Author(s)
      Ohtera A, Miyamae Y, Nakai N, Kawachi A, Kawada K, Han J, Isoda H, Neffati M, Akita T, Maejima K, Masuda S, Kambe T, Mori N, Irie K, and Nagao M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 440 Pages: 204-209

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] Regulation of zinc transport2013

    • Author(s)
      Kambe T(Edited by V. Culotta and R.A. Scott.)
    • Journal Title

      Encyclopedia of Inorganic and Bioinorganic Chemistry

      Volume: (John Wiley & Sons, Ltd: Chichester, UK) Pages: 301-309

    • Related Report
      2013 Final Research Report
  • [Journal Article] Compound heterozygous mutations in SLC30A2/ZnT2 results in low milk zinc concentrations : a novel mechanism for zinc deficiency in a breast-fed infant2013

    • Author(s)
      Itsumura N, Inamo Y, Okazaki F, Teranishi F, Narita H, Kambe T and Kodama H
    • Journal Title

      PLoS One

      Volume: 8

    • NAID

      120005289848

    • Related Report
      2013 Final Research Report
  • [Journal Article] 亜鉛代謝の必須分子として機能する亜鉛トランスポーター2013

    • Author(s)
      神戸大朋
    • Journal Title

      日本衛生学雑誌

      Volume: 68 Pages: 92-102

    • NAID

      120005477688

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] 消化管における亜鉛吸収のメカニズム2013

    • Author(s)
      神戸大朋(日本栄養・食糧学会監修, 駒井三千夫・神戸大朋 責任編集, 建帛社)
    • Journal Title

      亜鉛の機能と健康-新たにわかった多彩な機能

      Pages: 151-168

    • Related Report
      2013 Final Research Report
  • [Journal Article] Essential role of the zinc transporter ZIP9/SLC39A9 in regulating the activations of Akt and Erk in B-cell receptor signaling pathway in DT40 cells2013

    • Author(s)
      Taniguchi M, Fukunaka A, Hagihara M, Watanabe K, Kamino S, Kambe T, Enomoto S, and Hiromura M
    • Journal Title

      PLoS One

      Volume: 8

    • Related Report
      2013 Final Research Report
  • [Journal Article] Regulation of zinc transport2013

    • Author(s)
      Kambe T
    • Journal Title

      Encyclopedia of Inorganic and Bioinorganic Chemistry

      Volume: なし Pages: 301-309

    • Related Report
      2013 Annual Research Report 2012 Research-status Report
  • [Journal Article] Compound heterozygous mutations in SLC30A2/ZnT2 results in low milk zinc concentrations: a novel mechanism for zinc deficiency in a breast-fed infant2013

    • Author(s)
      Itsumura N, Inamo Y, Okazaki F, Teranishi F, Narita H, Kambe T* and Kodama H
    • Journal Title

      PLoS One

      Volume: 8 Issue: 5 Pages: e64045-e64045

    • DOI

      10.1371/journal.pone.0064045

    • NAID

      120005289848

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ZnT亜鉛トランスポーターの早期分泌経路における役割2013

    • Author(s)
      神戸大朋
    • Journal Title

      Biomed. Res. Trace Elements-日本微量元素学会誌

      Volume: 24 Pages: 110-116

    • NAID

      10031202789

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 消化管における亜鉛吸収のメカニズム2013

    • Author(s)
      神戸大朋
    • Journal Title

      亜鉛の機能と健康-新たにわかった多彩な機能

      Volume: なし Pages: 151-168

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Essential role of the zinc transporter ZIP9/SLC39A9 in regulating the activations of Akt and Erk in B-cell receptor signaling pathway in DT40 cells2013

    • Author(s)
      Taniguchi M, Fukunaka A, Hagihara M, Watanabe K, Kamino S, Kambe T, Enomoto S, Hiromura M
    • Journal Title

      PLOS ONE

      Volume: 8 Issue: 3 Pages: e58022-e58022

    • DOI

      10.1371/journal.pone.0058022

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Molecular Architecture and Function of ZnT transporters2012

    • Author(s)
      Kambe T(S. Lutsenko & J. M. Argüello (Eds.))
    • Journal Title

      Current Topics in Membranes-Metal Transporters

      Volume: 69(Elsevier Inc.: Academic Press) Pages: 199-220

    • NAID

      120004874008

    • Related Report
      2013 Final Research Report
  • [Journal Article] Establishment of a monitoring system to detect inhibition of mRNA processing2012

    • Author(s)
      Fujita K, Okamura M, Nishimoto S, Kurihara T, Momma K, Miyamae Y, Kambe T, Nagao M, Narita H, and Masuda S
    • Journal Title

      Biosci Biotechnol Biochem

      Volume: 76 Pages: 1248-1251

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] 亜鉛吸収を向上させる食品因子の探索-亜鉛栄養研究の現状と今後の展望を含めて-2012

    • Author(s)
      橋本彩子, 神戸大朋
    • Journal Title

      日本醸造協会誌

      Volume: 107 Pages: 836-841

    • NAID

      10031130348

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] Molecular Architecture and Function of ZnT transporters2012

    • Author(s)
      Kambe T
    • Journal Title

      Current Topics in Membranes

      Volume: 69 Pages: 199-220

    • DOI

      10.1016/b978-0-12-394390-3.00008-2

    • NAID

      120004874008

    • ISBN
      9780123943903
    • Related Report
      2012 Research-status Report
  • [Journal Article] Tissue non-specific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway2011

    • Author(s)
      Fukunaka A, Kurokawa Y, Teranishi F, Sekler I, Oda K, Ackland M. L, Faundez V, Hiromura M, Masuda S, Nagao M, Enomoto S and Kambe T
    • Journal Title

      J. Biol. Chem

      Volume: 286 Pages: 16363-16373

    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Journal Article] Molecular and genetic features of zinc transporters in physiology and pathogenesis2011

    • Author(s)
      Fukada T and Kambe T
    • Journal Title

      Metallomics

      Volume: 3 Pages: 662-674

    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Journal Article] An Overview of a Wide Range of Functions of ZnT and Zip Zinc Transporters in the Secretory Pathway2011

    • Author(s)
      Kambe T
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 75 Pages: 1036-1043

    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Journal Article] Enhancing recombinant protein production in human cell lines with a constitutive transport element and mRNA export proteins2011

    • Author(s)
      Aihara Y, Fujiwara N, Yamazaki T, Kambe T, Nagao M, Hirose Y, and Masuda S
    • Journal Title

      J Biotechnol

      Volume: 153 Pages: 86-91

    • Related Report
      2013 Final Research Report
  • [Journal Article] 消化管における必須微量金属の吸収-トランスポーターによる制御機構-2011

    • Author(s)
      橋本彩子, 辻徳治, 逸村直也, 神戸大朋
    • Journal Title

      Trace Nutrients Research-微量栄養素研究-

      Volume: 28 Pages: 89-94

    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Journal Article] 早期分泌経路における亜鉛酵素の活性化機構-ZnT 複合体による2-step mechanism を介したTNAP の活性化-2011

    • Author(s)
      神戸大朋
    • Journal Title

      Biomed. Res. Trace Elements-日本微量元素学会誌

      Volume: 22 Pages: 66-72

    • NAID

      10030442557

    • Related Report
      2013 Final Research Report
  • [Journal Article] 生体機能における亜鉛トランスポーターの重要性, -亜鉛トランスポーターをめぐる最近の知見-2011

    • Author(s)
      神戸大朋
    • Journal Title

      亜鉛栄養治療

      Volume: 1 Pages: 54-64

    • Related Report
      2013 Final Research Report
  • [Journal Article] Enhancing recombinant protein production in human cell lines with a constitutive transport element and mRNA export proteins2011

    • Author(s)
      Aihara Y, Fujiwara N, Yamazaki T, Kambe T, Nagao M, Hirose Y, Masuda S
    • Journal Title

      J Biotechnol

      Volume: 153 Issue: 3-4 Pages: 86-91

    • DOI

      10.1016/j.jbiotec.2011.03.024

    • NAID

      120003072129

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 早期分泌経路における亜鉛酵素の活性化機構 -ZnT複合体による2-step mechanismを介したTNAPの活性化-2011

    • Author(s)
      神戸大朋
    • Journal Title

      Biomed. Res. Trace Elements-日本微量元素学会誌

      Volume: 22 Pages: 66-72

    • NAID

      10030442557

    • Related Report
      2011 Research-status Report
  • [Journal Article] 生体機能における亜鉛トランスポーターの重要性-亜鉛トランスポーターをめぐる最近の知見-2011

    • Author(s)
      神戸大朋
    • Journal Title

      亜鉛栄養治療

      Volume: 1 Pages: 54-64

    • Related Report
      2011 Research-status Report
  • [Journal Article] 味噌など大豆発酵食品による亜鉛栄養改善の可能性-亜鉛吸収に機能するトランスポーターの発現に及ぼす効果-2011

    • Author(s)
      橋本彩子、神戸大朋
    • Journal Title

      日本醸造協会誌

      Volume: 106 Pages: 811-817

    • NAID

      10030301284

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] ZnT 亜鉛トランスポーターの早期分泌経路における役割

    • Author(s)
      神戸大朋
    • Journal Title

      Biomed. Res. Trace Elements-日本微量元素学会誌

      Volume: 24 Pages: 110-116

    • NAID

      10031202789

    • Related Report
      2013 Final Research Report
  • [Presentation] 亜鉛トランスポーターの機能 : 亜鉛欠乏症の観点から2014

    • Author(s)
      神戸大朋
    • Organizer
      日本農芸化学会2014年度大会
    • Place of Presentation
      東京
    • Year and Date
      2014-03-30
    • Related Report
      2013 Final Research Report
  • [Presentation] Zinc deficiency and dermatitis : From the standpoint of zinc transporter functions2014

    • Author(s)
      Taiho Kambe
    • Organizer
      The 91st Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-03-16
    • Related Report
      2013 Final Research Report
  • [Presentation] Cooperative functions of ZnT1, metallothionein and ZnT4 in the cytoplasm are required forfull activation of tissue non-specific alkaline phosphatase in the early secretory pathway2014

    • Author(s)
      Shigeyuki Fujimoto, Naoya Itsumura, Tokuji Tsuji and Taiho Kambe
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      米国(ロードアイランド)
    • Related Report
      2013 Final Research Report
  • [Presentation] Zinc transporters and Aging : Closing Remarks2013

    • Author(s)
      Taiho Kambe
    • Organizer
      X ISTERH CONFERENCE, TRACE ELEMENT RESEARCH, ON HEALTH AND DISEASES
    • Place of Presentation
      東京
    • Year and Date
      2013-11-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular mechanism of intestinal absorption of essential trace metals2013

    • Author(s)
      神戸大朋
    • Organizer
      石川県立大学腸内細菌共生機構学講座 開設記念シンポジウム
    • Place of Presentation
      金沢
    • Year and Date
      2013-10-04
    • Related Report
      2013 Final Research Report
  • [Presentation] Future direction of Zinc Biology in Signaling, Homeostasis and Diseases : Closing Remarks2013

    • Author(s)
      Taiho Kambe
    • Organizer
      The 86th Annual Meeting of the Japanese Biochemical Society 2013
    • Place of Presentation
      横浜
    • Year and Date
      2013-09-11
    • Related Report
      2013 Final Research Report
  • [Presentation] 消化管からの亜鉛吸収を促進する亜鉛トランスポーターを標的にした亜鉛栄養改善2013

    • Author(s)
      神戸大朋
    • Organizer
      JAACT 福井大会
    • Place of Presentation
      福井
    • Year and Date
      2013-07-19
    • Related Report
      2013 Final Research Report
  • [Presentation] 亜鉛欠乏予防と発酵食品2013

    • Author(s)
      神戸大朋
    • Organizer
      第99回 醸造調味食品セミナー
    • Place of Presentation
      東京
    • Year and Date
      2013-07-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 分泌経路に局在する亜鉛トランスポーターの機能に関する分子遺伝学的研究2013

    • Author(s)
      神戸大朋
    • Organizer
      第24回日本微量元素学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2013-06-30
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] 細胞内の亜鉛輸送機構 -trafficking, trasnfer, mobilization2013

    • Author(s)
      神戸大朋
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-30
    • Related Report
      2013 Final Research Report
  • [Presentation] Cooperative functions of ZnT1, metallothionein and ZnT4 in the cytoplasm are required fo2013

    • Author(s)
      Taiho Kambe
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      米国(ロードアイランド)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Evidence for facilitated transfer mechanism of cytosolic zinc to zinc transporters for expressing biological activity of zinc2012

    • Author(s)
      Taiho Kambe
    • Organizer
      The 85th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Related Report
      2013 Final Research Report
  • [Presentation] 味噌による亜鉛欠乏予防の可能性2012

    • Author(s)
      神戸大朋
    • Organizer
      みそ健康セミナー
    • Place of Presentation
      東京
    • Year and Date
      2012-11-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 消化管における亜鉛吸収のメカニズム2012

    • Author(s)
      神戸大朋
    • Organizer
      第1回最先端有機光機能材料シンポジウム
    • Place of Presentation
      長野
    • Year and Date
      2012-09-05
    • Related Report
      2013 Final Research Report
  • [Presentation] 亜鉛要求性酵素アルカリフォスファターゼ活性化の分子機構2012

    • Author(s)
      神戸大朋
    • Organizer
      第23回日本微量元素学会リサーチシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2012-07-05
    • Related Report
      2013 Final Research Report
  • [Presentation] 基礎研究から見た亜鉛バイオロジー2012

    • Author(s)
      神戸大朋
    • Organizer
      第23回日本微量元素学会 教育セミナー
    • Place of Presentation
      東京
    • Year and Date
      2012-07-05
    • Related Report
      2013 Final Research Report
  • [Presentation] 亜鉛バイオロジーを彩る亜鉛トランスポーターの科学2012

    • Author(s)
      神戸大朋
    • Organizer
      第4回岡山大&理研ジョイントシンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2012-06-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 消化管における亜鉛吸収のメカニズム2012

    • Author(s)
      神戸大朋
    • Organizer
      第66回日本栄養・食糧学会大会シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2012-05-20
    • Related Report
      2013 Final Research Report
  • [Presentation] 分泌経路の恒常性維持に機能する亜鉛トランスポーターの同定と解析2012

    • Author(s)
      神戸大朋
    • Organizer
      第26回JAACT シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2012-01-23
    • Related Report
      2013 Final Research Report
  • [Presentation] Mechanism for the activation of zinc-requiring enzymes by ZnT transporters in the early secretory pathway2012

    • Author(s)
      Taiho Kambe
    • Organizer
      International Society od Zinc Biology
    • Place of Presentation
      Australia (Melbourne)
    • Year and Date
      2012-01-16
    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Presentation] 亜鉛バイオロジーをめぐる最近の話題-亜鉛トランスポーター研究を中心に2012

    • Author(s)
      神戸大朋
    • Organizer
      福山大学グリーンサイエンス研究センター第2回公開講演会「食環境と健康」
    • Place of Presentation
      福山
    • Year and Date
      2012-01-06
    • Related Report
      2013 Final Research Report
  • [Presentation] 亜鉛と亜鉛トランスポーター2011

    • Author(s)
      神戸大朋
    • Organizer
      メタロチオネインおよびメタルバイオサイエンス研究会2011
    • Place of Presentation
      名古屋
    • Year and Date
      2011-12-08
    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Presentation] ニワトリDT40 細胞を活用した金属輸送体研究の新たな展開2011

    • Author(s)
      神戸大朋
    • Organizer
      フォーラム2011 : 衛生薬学・環境トキシコロジー
    • Place of Presentation
      金沢
    • Year and Date
      2011-10-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 早期分泌経路における亜鉛トランスポーターの役割2011

    • Author(s)
      神戸大朋
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Presentation] Mechanism for the activation of zinc-requiring enzymes by zinc transport complexes in the early secretory pathway2011

    • Author(s)
      Taiho Kambe
    • Organizer
      The 5th International Conference on Metals and Genetics, ICMG2011
    • Place of Presentation
      Kobe
    • Year and Date
      2011-09-05
    • Related Report
      2013 Final Research Report
  • [Presentation] 早期分泌経路における亜鉛要求性酵素の活性化機構2011

    • Author(s)
      神戸大朋
    • Organizer
      22回日本微量元素学会
    • Place of Presentation
      京都
    • Year and Date
      2011-07-01
    • Related Report
      2013 Final Research Report
  • [Presentation] 早期分泌経路における亜鉛要求性酵素の活性化機構2011

    • Author(s)
      神戸大朋
    • Organizer
      第22回日本微量元素学会
    • Place of Presentation
      京都
    • Related Report
      2011 Research-status Report
  • [Presentation] ニワトリDT40細胞を活用した金属輸送体研究の新たな展開2011

    • Author(s)
      神戸大朋
    • Organizer
      フォーラム2011:衛生薬学・環境トキシコロジー(招待講演)
    • Place of Presentation
      金沢
    • Related Report
      2011 Research-status Report
  • [Presentation] Mechanism for the activation of zinc-requiring enzymes by zinc transport complexes in the early secretory pathway2011

    • Author(s)
      Taiho Kambe
    • Organizer
      The 5th International Conference on Metals and Genetics, ICMG2011(招待講演)
    • Place of Presentation
      Kobe
    • Related Report
      2011 Research-status Report
  • [Presentation] 亜鉛トランスポーターの機能:亜鉛欠乏症の観点から

    • Author(s)
      神戸大朋
    • Organizer
      日本農芸化学会2014年度大会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Zinc deficiency and dermatitis:

    • Author(s)
      Taiho Kambe
    • Organizer
      The 91st Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      鹿児島
    • Related Report
      2013 Annual Research Report
  • [Presentation] Zinc transporters and Aging:

    • Author(s)
      Taiho Kambe
    • Organizer
      X ISTERH CONFERENCE TRACE ELEMENT RESEARCH ON HEALTH AND DISEASES
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Molecular mechanism of intestinal absorption of essential trace metals

    • Author(s)
      Taiho Kambe
    • Organizer
      石川県立大学腸内細菌共生機構学講座 開設記念シンポジウム
    • Place of Presentation
      金沢
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 消化管からの亜鉛吸収を促進する

    • Author(s)
      神戸大朋、橋本彩子、高橋正和
    • Organizer
      JAACTシンポジウム
    • Place of Presentation
      福井
    • Related Report
      2013 Annual Research Report
  • [Presentation] 亜鉛欠乏予防と発酵食品

    • Author(s)
      神戸大朋
    • Organizer
      第99回 醸造調味食品セミナー
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Future direction of Zinc Biology in Signaling, Homeostasis and Diseases

    • Author(s)
      Taiho Kambe
    • Organizer
      The 86th Annual Meeting of the Japanese Biochemical Society 2012
    • Place of Presentation
      横浜
    • Related Report
      2013 Annual Research Report
  • [Presentation] 消化管における亜鉛吸収のメカニズム

    • Author(s)
      神戸大朋
    • Organizer
      第66回日本栄養・食糧学会大会 シンポジウム
    • Place of Presentation
      東北大学(仙台)
    • Related Report
      2012 Research-status Report
  • [Presentation] 亜鉛バイオロジーを彩る亜鉛トランスポーターの科学

    • Author(s)
      神戸大朋
    • Organizer
      第4回岡山大&理研ジョイントシンポジウム
    • Place of Presentation
      岡山大学(岡山)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 亜鉛要求性酵素アルカリフォスファターゼ活性化の分子機構

    • Author(s)
      神戸大朋
    • Organizer
      第23回日本微量元素学会 リサーチシンポジウム
    • Place of Presentation
      砂防会館(東京)
    • Related Report
      2012 Research-status Report
  • [Presentation] 基礎研究から見た亜鉛バイオロジー

    • Author(s)
      神戸大朋
    • Organizer
      第23回日本微量元素学会 教育セミナー
    • Place of Presentation
      砂防会館(東京)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 消化管における亜鉛吸収のメカニズム

    • Author(s)
      神戸大朋
    • Organizer
      第1回 最先端有機光機能材料シンポジウム
    • Place of Presentation
      蓼科ホテル(長野)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 味噌による亜鉛欠乏予防の可能性

    • Author(s)
      神戸大朋
    • Organizer
      みそ健康セミナー
    • Place of Presentation
      パレスホテル東京(東京)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Evidence for facilitated transfer mechanism of cytosolic zinc to zinc transporters for expressing biological activity of zinc

    • Author(s)
      Taiho Kambe
    • Organizer
      The 85th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      マリンメッセ福岡(福岡)
    • Related Report
      2012 Research-status Report
  • [Presentation] 細胞内の亜鉛輸送機構- trafficking, trasnfer, mobilization

    • Author(s)
      神戸大朋
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Related Report
      2012 Research-status Report
  • [Presentation] 亜鉛バイオロジーをめぐる最近の話題 -亜鉛トランスポーター研究を中心に-

    • Author(s)
      神戸大朋
    • Organizer
      福山大学グリーンサイエンス研究センター 第2回 公開講演会「食環境と健康」(招待講演)
    • Place of Presentation
      福山
    • Related Report
      2011 Research-status Report
  • [Presentation] 分泌経路の恒常性維持に機能する亜鉛トランスポーターの同定と解析

    • Author(s)
      神戸大朋
    • Organizer
      第26回JAACTシンポジウム(招待講演)
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] 亜鉛トランスポーター複合体による亜鉛要求性酵素の活性化機構

    • Author(s)
      福中彩子, 黒川弥生, 永尾雅哉, 榎本秀一, 神戸大朋
    • Organizer
      日本動物細胞工学会2011 年度大会
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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