A surrogate virus for researches on foot-and-mouth disease
| Project/Area Number |
23658252
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied veterinary science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | ウイルス / レセプター / インテグリン / 口蹄疫 / 獣医学 |
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| Outline of Final Research Achievements |
To examine whether wildlife may be responsible for spread of foot-and-mouth disease (FMD), I searched cell receptor molecules for FMD virus (FMDV) on the organs of Japanese wild deer. I identified integrin alpha V, beta 6, and beta 8, which are supposed to be the main receptor molecules for FMDV, suggesting that such deer are susceptible to FMDV, although I have not authenticated their functional roles using bovine rhinovirus 2 as a surrogate of FMDV.
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Report
(5 results)
Research Products
(5 results)
