Development oftransplanted cell-tracking system usinMgRI
| Project/Area Number |
23659025
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Physical pharmacy
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| Research Institution | Sojo University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HIRAI Toshinori 熊本大学, 大学院・生命科学研究部, 准教授 (40274724)
TERASAWA Hiroaki 熊本大学, 大学院・生命科学研究部, 教授 (10300956)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 非侵襲性イメージング / 細胞移植 / 細胞トラッキング / MRI / 再生医学 / 13C / 再生医療 |
|---|
| Research Abstract |
Stable isotope13C-labeled human glioma cells were prepared by adding essential amino acid 13C-methionine in cell culture media. After subcutaneous transplantation of the cellsin mouse, we use a magnetic resonance imaging at 7T and obtained a chemical sift imaging of the13C-labeled cell cluster1.H/13C-CryoProbe in place of 1tHh/e13C-surface coil enablesus to reduce the scanning time significantly.metThoids may beuseful assaafe celltracking technique in postoperative management of cell transplant therapy.
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Report
(3 results)
Research Products
(14 results)
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[Journal Article] Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus.2013
Author(s)
Koga Y, Inazato M, Nakamura T, Hashikawa C, Chirifu M, Michi A, Yamashita T, Toma S, Kuniyasu A, Ikemizu S, Nakabeppu Y, Yamagata Y.
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Journal Title
Acta Crystallogr Sect F Struct Biol Cryst Commun
Volume: 69(Pt 1)
Issue: 1
Pages: 45-48
DOI
Related Report
Peer Reviewed
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