Project/Area Number |
23659978
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Periodontal dentistry
|
Research Institution | Hiroshima University |
Principal Investigator |
KURIHARA Hidemi 広島大学, 大学院・医歯薬保健学研究院, 教授 (40161765)
|
Co-Investigator(Kenkyū-buntansha) |
MIZUNO Noriyoshi 広島大学, 大学院・医歯薬保健学研究院, 助教 (60325181)
KAWAKAMI Hideshi 広島大学, 原爆放射線医科学研究所, 教授 (70253060)
IWATA Tomoyuki 広島大学, 病院, 助教 (30418793)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 侵襲性歯周炎 / 劣性遺伝 / 関連遺伝子 |
Research Abstract |
We detected the four mutations (ARHGF16, SLC2A7, SLC2A5, CASZ1) in patients with aggressive periodontitis by using homozygosity mapping and exome sequence. However, these mutations were not detected in our sporadic and control exomes. More samples are needed to be examined
|