| Project/Area Number |
23659992
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HANADA Nobuhiro 鶴見大学, 歯学部, 教授 (70180916)
NOMURA Yoshiaki 鶴見大学, 歯学部, 准教授 (90350587)
IMAI Susumu 鶴見大学, 歯学部, 講師 (80072958)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 石灰化 / 口腔細菌 / 歯石 / コリネバクテリウム / グラム陽性桿菌 / 界面活性剤 / ナノバクテリア / 唾液 |
|---|
| Research Abstract |
Corynebacterium matruchotii plays an important role in calcification of the biofilm. However, there are few epidemiological survey and clinical data in the association between C. matruchotii and carculus deposition.Because, a simple immunological detection method of C. matruchotii has not been developed.In this study, we aimed to find a specific antigen of C. matruchotii. The antigen will work for development of an immunological detection method.Twenty types of calcium-binding membrane proteins of C. matruchotii were isolated in this study. Those membrane proteins can be classified into acid proteins.
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