The molecular epidemiologic analysis of the mechanism of calculus formation: Role of the bacteria exist in saliva
| Project/Area Number |
23659992
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HANADA Nobuhiro 鶴見大学, 歯学部, 教授 (70180916)
NOMURA Yoshiaki 鶴見大学, 歯学部, 准教授 (90350587)
IMAI Susumu 鶴見大学, 歯学部, 講師 (80072958)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 石灰化 / 口腔細菌 / 歯石 / コリネバクテリウム / グラム陽性桿菌 / 界面活性剤 / ナノバクテリア / 唾液 |
|---|
| Research Abstract |
Corynebacterium matruchotii plays an important role in calcification of the biofilm. However, there are few epidemiological survey and clinical data in the association between C. matruchotii and carculus deposition.Because, a simple immunological detection method of C. matruchotii has not been developed.In this study, we aimed to find a specific antigen of C. matruchotii. The antigen will work for development of an immunological detection method.Twenty types of calcium-binding membrane proteins of C. matruchotii were isolated in this study. Those membrane proteins can be classified into acid proteins.
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Report
(4 results)
Research Products
(23 results)
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[Journal Article] Salivary biomarkers for predicting the progression of chronic periodontitis.2012
Author(s)
Nomura Y, Shimada Y, Hanada N, Numabe Y, Kamoi K, Sato T, Gomi K, Arai T, Inagaki K, Fukuda M, Noguchi T, Yoshie H
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Journal Title
Arch Oral Biol.
Volume: 57(4)
Pages: 413-442
Related Report
Peer Reviewed
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[Presentation] 唾液検査の標準化に関する検討2012
Author(s)
花田 信弘, 野村 義明, 今井 奬, 村田 貴俊, 山田 秀則, 角田 衣理加, 宮之原 真由, 岡田 彩子, 阿保 備子, 福田 雄
Organizer
第61回日口腔衛生学会
Place of Presentation
神奈川歯科大学 (神奈川)
Related Report
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[Presentation] チンパンジー口腔由来のミュータンスレンサ球菌様細菌に関する研究2011
Author(s)
阿保備子, 宮之原真由, 今井奬, 岡本公彰, 斉藤渉, 山口貴央, 井川知子, 小川匠, 野村義明, 宮部貴子, 桃井保子, 花田信弘
Organizer
鶴見大学歯学会第37回総会および第73回例会
Place of Presentation
鶴見大学会館メインホール (神奈川県)
Related Report
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[Presentation] iPS細胞の安全性に関する検討2011
Author(s)
野村義明, 石川美佐緒, 新井千博, 八城祐一, 野田晃司, 山口貴央, 阿保備子, 角田衣理加, 山田秀則, 今井奨, 中村芳樹, 花田信弘
Organizer
第60回日本口腔衛生学会
Place of Presentation
日本大学松戸歯学部 (千葉県)
Related Report
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