The gene expression analysis in kidney-like structure compared to Embryonic kidney and adult kidney
| Project/Area Number |
23700537
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 腎臓 / 再生 / 臓器構築 / 遺伝子発現 / 臓器再生 / 幹細胞 |
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| Research Abstract |
We have succeeded to reconstitute the renal structure from renal stem/ progenitor cells in Vitro. However, it is unknown whether the gene expression in kidney-like structure from renal stem/progenitor cells, in embryonic kidney and in adult kidney is close or not. Here we performed to elucidate the concordance rate between the gene expression in kidney-like structure and the gene expression in embryonic kidney and adult kidney by DNA analysis. The gene expression of kidney-like structure was very close to the embryonic kidney, and was on the time course of kidney development. However, it should be analyze more detail.
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Report
(3 results)
Research Products
(28 results)
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[Journal Article] Right hypoplastic kidney2012
Author(s)
Ayu Ogawa, Shinji Kitamura,Kazunori Nakayama, Hitoshi Sugiyama, Naoya Morisada
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Journal Title
Kazumoto Iijima and Hirofumi Makino. Kidney In
Volume: 82(9)
Pages: 1037-1037
Related Report
Peer Reviewed
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[Journal Article] The frequency of Fabry disease with the E66Q variant in the α-galactosidase A gene in Japanese dialysis patients: a case report and a literature review2012
Author(s)
Kikumoto Y, Sugiyama H, Morinaga H, Inoue T, Takiue K, Kitagawa M, Saito D, Takatori Y, Kinomura M, Kitamura S, Akagi S, Sada K, Nakao K, Maeshima Y, Kitayama H, Makino H
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Journal Title
Clin Nephrol
Volume: 78(3)
Pages: 224-9
Related Report
Peer Reviewed
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[Journal Article] Acatalasemic mice are mildly susceptible to adriamycin nephropathy and exhibit increased albuminuria and glomerulosclerosis2012
Author(s)
Takiue K, Sugiyama H, Inoue T, Morinaga H, Kikumoto Y, Kitagawa M, Kitamura S, Maeshima Y, Wang DH, Masuoka N, Ogino K, Makino H
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Journal Title
BMC Nephrol
Volume: 13(1)
Pages: 14-14
Related Report
Peer Reviewed
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[Journal Article] Acatalasemic mice are mildly susceptible to adriamycin nephropathy and exhibit increased albuminuria and glomerulosclerosis.2012
Author(s)
Takiue K, Sugiyama H, Inoue T, Morinaga H, Kikumoto Y, Kitagawa M, Kitamura S, Maeshima Y, Wang DH, Masuoka N, Ogino K, Makino H.
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Journal Title
BMC Nephrol.
Volume: 13(1)
Issue: 1
Pages: 14-14
DOI
Related Report
Peer Reviewed
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