Project/Area Number |
23700537
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Biomedical engineering/Biological material science
|
Research Institution | Okayama University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 腎臓 / 再生 / 臓器構築 / 遺伝子発現 / 臓器再生 / 幹細胞 |
Research Abstract |
We have succeeded to reconstitute the renal structure from renal stem/ progenitor cells in Vitro. However, it is unknown whether the gene expression in kidney-like structure from renal stem/progenitor cells, in embryonic kidney and in adult kidney is close or not. Here we performed to elucidate the concordance rate between the gene expression in kidney-like structure and the gene expression in embryonic kidney and adult kidney by DNA analysis. The gene expression of kidney-like structure was very close to the embryonic kidney, and was on the time course of kidney development. However, it should be analyze more detail.
|