Development of metallic micro-porous surface modification techniques for promoting neointimal endothelium

Research Project

Project/Area Number	23700538
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Biomedical engineering/Biological material science
Research Institution	The University of Tokushima
Principal Investigator	SEKINE Kazumitsu 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (50447182)
Project Period (FY)	2011 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords	人工臓器工学 / 再生医工学 / 複合生体材料 / 人工臓器 / 血液接触表面 / 表面改質 / 国際情報交流 / 多孔体
Research Abstract	We have developed and fabricated the titanium(Ti) micro-porous specimens with the several variation of the shape, the size and the thickness, by sintering the Ti micro powder and their binder. These specimens were evaluated their characteristics of porous, several mechanical strength, and cell compatibility and morphology. These results indicated that the Ti micro-porous could show the good performance of porous character, mechanical strength and neointhimal growth as the scaffold.