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Development of regulating the human circadian rhythm by physical exercise

Research Project

Project/Area Number 23700770
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Sports science
Research InstitutionHokkaido University

Principal Investigator

YAMANAKA Yujiro  北海道大学, 大学院・医学研究科, 助教 (20528343)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsスポーツ生理学 / 生体リズム / 身体運動 / 高照度光 / 時差シミュレーション / ヒト / メラトニン / 睡眠脳波
Research Abstract

In the present study, we examined whether timed physical exercise accelerated phase shift of circadian melatonin rhythms under bright light conditions. Fifteen male subjects spent 14 days in an isolation unit without knowing the time of day. On the last day of advanced sleep schedule, the mean peak phase of plasma melatonin rhythm in the exercise group significantly phase advanced on the first day of free-run, whereas it did not in the control group. In conclusion, timed physical exercise accelerates re-entrainment of plasma melatonin rhythm to an 8-h phase advance of sleep schedule.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (18 results)

All 2013 2012 2011

All Journal Article (2 results) (of which Peer Reviewed: 1 results) Presentation (15 results) Book (1 results)

  • [Journal Article] Daily exposure to cold phase-shifts circadian clock ofneonatal rat in vivo2013

    • Author(s)
      Yoshikawa T, Matsuno A, Yamanaka Y, Nishide S, Honma S, Honma K
    • Journal Title

      Eur J Neurosci

      Volume: 37(3) Pages: 491-497

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 生物リズムに関わる神経系. 脳とこころのプライマリケア2012

    • Author(s)
      山仲勇二郎、本間さと、本間研一
    • Journal Title

      シナジー

      Volume: 5巻 Pages: 308-31

    • Related Report
      2012 Final Research Report
  • [Presentation] 高照度光での身体運動がヒト概日リズムの位相調節に与える影響2013

    • Author(s)
      山仲勇二郎、橋本聡子、増渕悟、夏堀晃世、西出真也、本間さと、本間研一
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京都、タワーホール船堀
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 高照度光下での身体運動がヒト概日リズムの位相調節に与える影響2013

    • Author(s)
      山仲勇二郎
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京都、タワーホール船堀
    • Related Report
      2012 Annual Research Report
  • [Presentation] 高照度光下での身体運動は8時間位相前進シフトした生活スケジュールへの血中メラトニンリズムの再同調を促進する2013

    • Author(s)
      山仲勇二郎
    • Organizer
      第38回日本睡眠学会定期学術集会
    • Place of Presentation
      秋田市、秋田県民会館他
    • Related Report
      2012 Annual Research Report
  • [Presentation] 明暗周期位相変位後のマウス行動リズムを制御する視交叉上核領域振動体の探2012

    • Author(s)
      山仲勇二郎、本間さと、本間研一
    • Organizer
      第19回日本時間生物学会学術大会
    • Place of Presentation
      札幌市、北海道大学学術交流会館
    • Year and Date
      2012-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 母子同調因子としての環境温: in vivoにおける視交叉上核の温度感受性2012

    • Author(s)
      吉川朋子、松野亜美、山仲勇二郎、西出真也、本間さと、本間研一
    • Organizer
      第19回日本時間生物学会学術大会
    • Place of Presentation
      札幌市、北海道大学学術交流会館
    • Year and Date
      2012-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 1日1食の制限食事がヒトに給餌性リズムを発現させるか2012

    • Author(s)
      本間研一、山仲勇二郎、橋本聡子、本間さと
    • Organizer
      第19回日本時間生物学会学術大会
    • Place of Presentation
      札幌市、北海道大学学術交流会館
    • Year and Date
      2012-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 腕時計型行動計により計測されたヒト行動リズムから内的脱同調の有無を判断する2012

    • Author(s)
      橋本聡子、本間研一、山仲勇二郎、本間さと
    • Organizer
      第19回日本時間生物学会学術大会
    • Place of Presentation
      札幌市、北海道大学学術交流会館
    • Year and Date
      2012-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 時間隔離実験室を使用したヒト生物時計の非光同調機構の解析2012

    • Author(s)
      山仲勇二郎、橋本聡子、高須奈々、棚橋祐典、西出真也、本間さと、本間研一
    • Organizer
      第37回日本睡眠学会定期学術集会
    • Place of Presentation
      横浜市、パシフィコ横浜
    • Year and Date
      2012-06-28
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] 運動と生体リズム2012

    • Author(s)
      山仲勇二郎、橋本聡子、増渕悟、夏堀晃世、西出真也、本間さと、本間研一
    • Organizer
      第37回日本睡眠学会定期学術集会
    • Place of Presentation
      横浜市、パシフィコ横浜
    • Year and Date
      2012-06-28
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] 高照度光下での身体運動がヒト概日リズムの位相調節に与える影響2012

    • Author(s)
      山仲勇二郎、橋本聡子、増渕悟、夏堀晃世、西出真也、本間さと、本間研一
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本市、松本文化会館
    • Year and Date
      2012-03-31
    • Related Report
      2012 Final Research Report
  • [Presentation] 高照度光下での身体運動がヒト概日リズムの位相調節に与える影響.2012

    • Author(s)
      山仲勇二郎, 橋本聡子, 増渕悟, 亀山晃世, 西出真也, 本間さと, 本間研一.
    • Organizer
      第89回日本生理学会
    • Place of Presentation
      長野県松本文化会館(松本市)
    • Related Report
      2011 Research-status Report
  • [Presentation] Effect of physical exercise on re-entrainment of human circadian rhythms to an 8 h advanced sleep schedule under bright light coditions2011

    • Author(s)
      Yujiro Yamanaka, Satoko Hashimoto, Satoru Masubuchi, Akiyo Kameyama, Shin-ya Nishide, Sato Honma, Ken-ichi Honma
    • Organizer
      International Symposium on Photic Bioimaging Satellite Symposium of Worldsleep 2011 on Human Circadian Clock- the 50th anniversary oftemporal isolation study- (Sapporo, Japan.
    • Place of Presentation
      (Kyoto, Japan.Keio plaza hotel
    • Year and Date
      2011-01-23
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of scheduled physical exercise on re-entrainment of human circadian rhythms to an 8 h advanced sleep schedule in isolation facility2011

    • Author(s)
      Yujiro Yamanaka, Satoko Hashimoto, Satoru Masubuchi, Akiyo Kameyama, Shin-ya Nishide, Sato Honma, Ken-ichi Honma
    • Organizer
      Abstract Symosium. Translational research of lighting effects on biological rhythm and sleep. WorldSleep 2011 (Kyoto, Japan.
    • Place of Presentation
      Kyoto InternationalConference Hall
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of scheduled physical exercise on re-entrainment of human circadian rhythms to an 8 h advanced sleep schedule in isolation facility.2011

    • Author(s)
      Yujiro Yamanaka, Satoko Hashimoto, Satoru Masubuchi, Akiyo Kameyama, Shin-ya Nishide, Sato Honma, Ken-ichi Honma
    • Organizer
      WorldSleep 2011
    • Place of Presentation
      京都国際会館(京都市)
    • Related Report
      2011 Research-status Report
  • [Presentation] Effect of physical exercise on re-entrainment of human circadian rhythms to an 8 h advanced sleep schedule under bright light coditions.2011

    • Author(s)
      Yujiro Yamanaka, Satoko Hashimoto, Satoru Masubuchi, Akiyo Kameyama, Shin-ya Nishide, Sato Honma, Ken-ichi Honma
    • Organizer
      International Symposium on Photic Bioimaging Satellite Symposium of Worldsleep 2011 on Human Circadian Clock- the 50th anniversary of temporal isolation study-
    • Place of Presentation
      京王プラザホテル札幌(札幌市)
    • Related Report
      2011 Research-status Report
  • [Book] 体内時計の生理機能. 体内時計の科学と産業応用2011

    • Author(s)
      山仲勇二郎、本間さと
    • Publisher
      シーエムシー出版
    • Related Report
      2012 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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