| Project/Area Number |
23700913
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Kyoto Prefectural University |
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Principal Investigator |
WADA Sayori 京都府立大学, 大学院・生命環境科学研究科, 講師 (60420709)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 特殊栄養食品 / 炎症性腸疾患 / 機能性ペプチド / 発酵食品 / 腸内細菌 / 抗炎症 / ペプチド / 日本酒 / 食品因子 / 生体内活性 / Autofocusing |
|---|
| Research Abstract |
The number of Inflammatory bowel disease (IBD) patients is increasing and the change in eating habit is one of the factor of these increasing. It has been reported that several fermented foods have improving effect of IBD. We determined the anti-inflammatory effect of Japanese rice wine-derived peptide on dextran sulfate sodium (DSS)-induced acute colitis in mice. Some peptide derived from Japanese rice wine showed the colitis improving effect at the concentration of few mg/kg/day. This result indicates that Japanese sake-derived components have a potent of therapeutic agent on IBD.
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