Exploration of bioactive natural products which induce selective apoptosis in tumor cells from Kampo formulas
| Project/Area Number |
23710249
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Living organism molecular science
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| Research Institution | Chiba University |
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Principal Investigator |
TOUME Kazufumi 千葉大学, 大学院・薬学研究院, 助教 (80563981)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 天然物化学 / TRAIL / アポトーシス / 生物活性天然物 / がん / 生薬 / DR5 |
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| Research Abstract |
In this study, we examined extracts of natural resources including Kampo formulas for bioactive natural products which induce selective apoptosis in tumor cells. As a result of this screening study we have isolated several active compounds. The mode of action for isolated compounds was also investigated.
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Report
(3 results)
Research Products
(60 results)
