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Study of compounds that influence facultative symbiosis between coral and seagrass

Research Project

Project/Area Number 23710258
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Living organism molecular science
Research InstitutionUniversity of the Ryukyus

Principal Investigator

TERUYA TOSHIAKI  琉球大学, 教育学部, 准教授 (90375428)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsリュウキュウスガモ / エダコモンサンゴ / 混合群落 / コユビミドリイシ / エダコモンサンゴ幼生 / カフェ酸 / 褐虫藻 / 相利関係
Research Abstract

In this study, we examined compounds that influence facultative symbiosis between coral Montipora digitata and seagrass Thalassa hemprichii, which can be seen near Bise on the west coast of Okinawa Island. Acropora sp.1 was used as a control. We evaluated the influence of a crude extract of seagrass T. hemprichii against coral larvae. The seagrass T. hemprichii was directly harvested in Okinawa Prefecture. A crude organic extract of this material was subjected to bioassay-guided (toxicity against coral larvae) fractionation by solvent partition, ODS-HPLC, to yield caffeic acid. Morphological changes of lavae of Acropora sp.1 were induced by exposure to 0.0018 mg/ml-0.18 mg/ml caffeic acid. On the other hand, no morphological changes of lavae of M. digitata were induced at same concentration.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (48 results)

All 2014 2013 2012 2011 Other

All Journal Article (23 results) (of which Peer Reviewed: 20 results) Presentation (23 results) Book (2 results)

  • [Journal Article] Fargesin, a component of Flos Magnoliae, stimulates glucose uptake in L6 myotubes2013

    • Author(s)
      Choi, S-S.; Cha, B-Y.; Choi, B-K.; Lee, Y-S.; Yonezawa, T.; Teruya, T.; Nagai, K.; Woo, J-T.
    • Journal Title

      Journal of Natural Medicines

      Volume: 67 Pages: 320-326

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bisebromoamide, an extract from Lyngbya species, induces apoptosis through ERK and mTOR inhibitions in renal cancer cells2013

    • Author(s)
      Suzuki, K.; Mizuno, R.; Suenaga, K.; Teruya, T.; Tanaka, N.; Kosaka, T.; Oya, M.
    • Journal Title

      Cancer Medicine

      Volume: 2 Pages: 32-39

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Apoptosis-inducing activity of the actin-depolymerizing agent aplyronine A and its side-chain derivatives2013

    • Author(s)
      Ohno, O.; Morita, M.; Kitamura, K.; Teruya, T.; Yoneda, K.; Kita, M.; Kigoshi, H.; Suenaga, K.
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 23 Pages: 1467-1471

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nobiletin improves obesity and insulin resistance in high-fat diet-induced obese mice2013

    • Author(s)
      Lee, Y-S.; Cha, B-Y.; Choi, S-S.; Choi, B-K.; Yonezawa, T.; Teruya, T.; Nagai, K.; Woo, J-T.
    • Journal Title

      Journal of Nutritional Biochemistry

      Volume: 24 Pages: 156-162

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Honokiol and magnolol stimulate glucose uptake by activating PI3K-dependent Akt in L6 myotubes2012

    • Author(s)
      Choi, S-S.; Cha, B-Y.; Lee, Y.-S.; Yonezawa, T.; Teruya, T.; Nagai, K.; Woo, J-T.
    • Journal Title

      Bio Factors

      Volume: 38 Pages: 372-377

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice2012

    • Author(s)
      Lee, Y-S.; Cha, B-Y.; Choi, S-S.; Harada, Y.; Choi, B-K.; Yonezawa, T.; Teruya, T.; Nagai, K.; Woo, J-T.
    • Journal Title

      Bio Factors

      Volume: 38 Pages: 300-308

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of veraguensin and galgravin on osteoclast differentiation and function2012

    • Author(s)
      Asai, M.; Lee, J-W.; Itakura, Y.; Choi, B-K.; Yonezawa, T.; Teruya, T.; Cha, B-Y.; Ohnishi, M.; Yamaguchi, A.; Woo, J-T.
    • Journal Title

      Cytotechnology

      Volume: 64 Pages: 315-322

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Isolation and structures of biselyngbyasides B, C, and D from the marine cyanobacterium Lyngbya sp., and the biological activities of biselyngbyasides2012

    • Author(s)
      Morita, M.; Ohno, O.; Teruya, T.; Yamori, T.; Inuzuka, T.; Suenaga, K.
    • Journal Title

      Tetrahedron

      Volume: 68 Pages: 5984-5990

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Biselyngbyaside, isolated from marine cyanobacteria, inhibits osteoclastogenesis and induces apoptosis in mature osteoclasts2012

    • Author(s)
      Yonezawa, T.; Mase, N.; Sasaki, H.; Teruya, T.; Hasegawa, S-. Cha, B-Y. Yagasaki, K. Suenaga, K. Nagai, K. Woo, J-T.
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: 113 Pages: 440-448

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Nobiletin improves obesity and insulin resistance in high-fat diet-induced obese mice2012

    • Author(s)
      Young-Sil Lee, Byung-Yoon Cha, Sun-Sil Choi, Bong-Keun Choi, Takayuki Yonezawa, Toshiaki Teruya, Kazuo Nagai, Je-Tae Woo.
    • Journal Title

      Journal of Nutritional Biochemistry

      Volume: 24 Issue: 1 Pages: 156-162

    • DOI

      10.1016/j.jnutbio.2012.03.014

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice2012

    • Author(s)
      Young-Sil Lee, Byung-Yoon Cha, Sun-Sil Choi, Yumiko Harada, Bong-Keun Choi, Takayuki Yonezawa, Toshiaki Teruya, Kazuo Nagai, Je-Tae Woo.
    • Journal Title

      BioFactors

      Volume: 38 Issue: 4 Pages: 1872-8081

    • DOI

      10.1002/biof.1022

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Honokiol and magnolol stimulate glucose uptake by activating PI3K-dependent Akt in L6 myotubes2012

    • Author(s)
      Sun-Sil Choi, Byung-Yoon Cha, Young-Sil Lee, Takayuki Yonezawa, Toshiaki Teruya, Kazuo Nagai, Je-Tae Woo.
    • Journal Title

      BioFactors

      Volume: 38 Issue: 5 Pages: 372-377

    • DOI

      10.1002/biof.1029

    • Related Report
      2012 Research-status Report
  • [Journal Article] Allelopathy of red pine : Isolation and identification of an allelopathic substance in red pine needles2011

    • Author(s)
      Kato-Noguchi, H.; Fushimi, Y.; Tanaka, Y.; Teruya, T.; Suenaga, K.
    • Journal Title

      Plant Growth Regulation

      Volume: 65 Pages: 299-304

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two potent allelopathic substances in cucumber plants2011

    • Author(s)
      Kato-Noguchi, H.; Le, T. H.; Teruya, T.; Suenaga, K.
    • Journal Title

      Scientia Horticulturae (Amsterdam, Netherlands)

      Volume: 129 Pages: 894-897

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Honokiol enhances adipocyte differentiation by potentiating insulin signaling in 3T3-L1 preadipocytes2011

    • Author(s)
      Choi, S.; Cha, B-Y.; Iida, K.; Sato, M.; Lee, Y-S.; Teruya, T.; Yonezawa, T.; Nagai, K.; Woo, J-T.
    • Journal Title

      Journal of Natural Medicines

      Volume: 65 Pages: 424-430

    • NAID

      10029461740

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling2011

    • Author(s)
      Yonezawa, T.; Lee, J-W.; Hibino, A.; Asai, M.; Hojo, H.; Cha, B-Y.; Teruya, T.; Nagai, K.; Chung, U-l; Yagasaki, K.; Woo, Je-Tae.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 409 Pages: 260-265

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] N,N'-diphenethylurea isolated from Okinawan ascidian Didemnum molle enhances adipocyte differentiation in 3T3-L1 cells2011

    • Author(s)
      Choi, S-S.; Cha, B-Y.; Kagami, I.; Lee, Y-S.; Sasaki, H.; Suenaga, K.; Teruya, T.; Yonezawa, T.; Nagai, K.; Woo, J-T.
    • Journal Title

      Journal of Antibiotics

      Volume: 64 Pages: 277-280

    • NAID

      10030638432

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Artepillin C, as a PPARγ ligand, enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells2011

    • Author(s)
      Choi, S-S.; Cha, B-Y.; Iida, K.; Lee, Y-S.; Yonezawa, T.; Teruya, T.; Nagai, K.; Woo, J-T.
    • Journal Title

      Biochemical Pharmacology

      Volume: 81 Pages: 925-933

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Revised structure and structure-activity relationship of bisebromoamide and structure of norbisebromoamide from the marine cyanobacterium Lyngbya sp2011

    • Author(s)
      Sasaki, H.; Teruya, T.; Fukazawa, H.; Suenaga, K.
    • Journal Title

      Tetrahedron

      Volume: 67 Pages: 990-994

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo2011

    • Author(s)
      Yonezawa, T.; Hasegawa, S.; Asai, M.; Ninomiya, T.; Sasaki, T.; Cha, B-Y.; Teruya, T.; Ozawa, H.; Yagasaki, K.; Nagai, K.; Woo, J.-T.
    • Journal Title

      European Journal of Pharmacology

      Volume: 650 Pages: 511-518

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Revised structure and structure-activity relationship of bisebromoamide and structure of norbisebromoamide from the marine cyanobacterium Lyngbya sp.2011

    • Author(s)
      Sasaki Hiroaki, Teruya Toshiaki, Fukazawa Hidesuke, and Suenaga Kiyotake.
    • Journal Title

      Tetrahedron

      Volume: 67 Issue: 5 Pages: 990-994

    • DOI

      10.1016/j.tet.2010.11.106

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Two potent allelopathic substances in cucumber plants2011

    • Author(s)
      Kato-Noguchi Hisashi, Le Thi Ho, Teruya Toshiaki, and Suenaga Kiyotake.
    • Journal Title

      Scientia Horticulturae

      Volume: 129 Issue: 4 Pages: 894-897

    • DOI

      10.1016/j.scienta.2011.04.031

    • Related Report
      2011 Research-status Report
  • [Journal Article] Allelopathy of red pine: isolation and identification of an allelopathic substance in red pine needles2011

    • Author(s)
      Kato-Noguchi Hisashi, Fushimi Yoshiko, Tanaka Yukitoshi, Teruya Toshiaki, and Suenaga Kiyotake.
    • Journal Title

      Plant Growth Regulation

      Volume: 65 Issue: 2 Pages: 299-304

    • DOI

      10.1007/s10725-011-9601-2

    • Related Report
      2011 Research-status Report
  • [Presentation] 高脂肪食誘導肥満マウスにおけるシークワーサーエキスの抗肥満効果2014

    • Author(s)
      車炳允、浅井みどり、照屋俊明、米澤貴之、金靜、永井和夫、禹済泰
    • Organizer
      日本農芸学会2014年度大会
    • Place of Presentation
      川崎
    • Year and Date
      2014-03-28
    • Related Report
      2013 Final Research Report
  • [Presentation] 高脂肪食誘導肥満マウスにおけるシークワーサーエキスの抗肥満効果2014

    • Author(s)
      車炳允・浅井みどり・照屋俊明・米澤 貴之・金孝靜・永井和夫・禹済泰
    • Organizer
      日本農芸学会2014年度大会
    • Place of Presentation
      明治大学生田キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] 破骨細胞の機能に対するBiselymgbyasideの作用2013

    • Author(s)
      照屋俊明、米澤貴之、間瀬直美、佐々木宏明、末永聖武、車炳允、禹済泰、永井和夫
    • Organizer
      第15回マリンバイオテクノロジー学会大会
    • Place of Presentation
      那覇
    • Year and Date
      2013-06-01
    • Related Report
      2013 Final Research Report
  • [Presentation] 海洋微細藻類由来新規チアゾール化合物tomurulineの構造と生物活性2013

    • Author(s)
      大野修、佐名恭平、照屋俊明、清水史郎、末永聖武
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 海洋産マクロリド Biselyngbyaside類の構造と生物活性2013

    • Author(s)
      森田真布、大野修、照屋俊明、佐々木宏明、末永聖武
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 海洋シアノバクテリア由来のマクロリド biselyngbyolide Bの単離と構造2013

    • Author(s)
      森田真布、大野修、照屋俊明、佐々木宏明、末永聖武
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-25
    • Related Report
      2013 Final Research Report
  • [Presentation] アクチン脱重合活性物質レイジスポンジオリド Aの合成研究2013

    • Author(s)
      鈴木一司、秋山、聡史、鳥居原英輔、照屋俊明、大野修、末永聖武
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 破骨細胞の機能に対するBiselyngbyasideの作用2013

    • Author(s)
      照屋俊明・米澤貴之・間瀬直美・佐々木宏明・末永聖武・車炳允・禹済泰・永井和夫
    • Organizer
      第15回マリンバイオテクノロジー学会
    • Place of Presentation
      沖縄県市町村自治会館
    • Related Report
      2013 Annual Research Report
  • [Presentation] アクチン脱重合活性物質Reidispongiolide Aの合成研究2012

    • Author(s)
      鈴木一司、秋山、聡史、鳥居原英輔、深澤英吾、照屋俊明、大野修、末永聖武
    • Organizer
      第54回天然有機化合物討論会
    • Place of Presentation
      世田谷
    • Year and Date
      2012-09-18
    • Related Report
      2013 Final Research Report
  • [Presentation] 海洋シアノバクテリア由来の新規マクロリドLeptolyngbyolide類の生物活性2012

    • Author(s)
      森田真布、大野修、照屋俊明、末永聖武
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2012-03-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 海洋シアノバクテリア由来のマクロリドBiselyngbyaside類の単離と構造2012

    • Author(s)
      森田真布、大野修、照屋俊明、末永聖武
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2012-03-27
    • Related Report
      2013 Final Research Report
  • [Presentation] アクチン脱重合活性物質レイジスポンジオリドAの合成研究2012

    • Author(s)
      鈴木一司、鳥居原英輔、秋山、聡史、照屋俊明、大野修、末永聖武
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2012-03-27
    • Related Report
      2013 Final Research Report
  • [Presentation] リュウキュウスガモ抽出物が付着生物幼生に与える影響について2012

    • Author(s)
      末吉康佑、中野義勝、井口亮、照屋俊明
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2012-03-26
    • Related Report
      2013 Final Research Report
  • [Presentation] 海洋シアノバクテリア由来新規環状デプシペプチドの単離と構 造決定2012

    • Author(s)
      梶山雄司・大野修・照屋俊明・末永聖武
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス
    • Related Report
      2011 Research-status Report
  • [Presentation] リュウキュウスガモ抽出物が付着生物幼生に与える影響につ いて2012

    • Author(s)
      末吉康佑・中野義勝・井口亮・照屋俊明
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス
    • Related Report
      2011 Research-status Report
  • [Presentation] 海洋シアノバクテリア由来の新規マクロリドLeptolyngbyolide 類の生物活性2012

    • Author(s)
      森田真布・大野修・照屋俊明・末永聖 武
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス
    • Related Report
      2011 Research-status Report
  • [Presentation] 海洋シアノバクテリア由来のマクロリドBiselyngbyaside類の単 離と構造2012

    • Author(s)
      森田真布・大野修・照屋俊明・末永聖武
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス
    • Related Report
      2011 Research-status Report
  • [Presentation] アクチン脱重合活性物質レイジスポンジオリドA の合成研究2012

    • Author(s)
      鈴木一司・鳥居原英輔・秋山聡史・照屋俊明・大野 修・末永聖武
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス
    • Related Report
      2011 Research-status Report
  • [Presentation] 海洋シアノバクテリア由来の新規マクロリド Biselyngbyaside類の構造と生物活性2011

    • Author(s)
      森田真布、大野修、照屋俊明、北将樹、木越英夫、北村和大、平田邦生、末永聖武
    • Organizer
      第53回天然有機化合物討論会
    • Place of Presentation
      大阪
    • Year and Date
      2011-09-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 海洋産マクロリドBiselyngbyaside類の構造と生物活性

    • Author(s)
      森田真布・大野修・照屋俊明・佐々木宏明・末永聖武
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学 びわこ・くさつキャンパス(BKC)
    • Related Report
      2012 Research-status Report
  • [Presentation] 海洋シアノバクテリア由来のマクロリドbiselyngbyolide Bの単離と構造

    • Author(s)
      渡邊絢音・森田真布・大野修・照屋俊明・末永聖武
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学 びわこ・くさつキャンパス(BKC)
    • Related Report
      2012 Research-status Report
  • [Presentation] アクチン脱重合活性物質レイジスポンジオリドAの合成研究

    • Author(s)
      鈴木一司・秋山聡史・鳥居原英輔・照屋俊明・大野修・末永聖武
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学 びわこ・くさつキャンパス(BKC)
    • Related Report
      2012 Research-status Report
  • [Presentation] 海洋微細藻類由来新規チアゾール化合物tomurulineの構造と生物活性

    • Author(s)
      大野修・佐名恭平・照屋俊明・清水史郎・末永聖武
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学 びわこ・くさつキャンパス(BKC)
    • Related Report
      2012 Research-status Report
  • [Book] Marine Pharmacognosy2013

    • Author(s)
      Toshiaki Teruya, Osamu Ohno, Kiyotake Suenaga.
    • Publisher
      CRC Press (Taylor and Francis Group)
    • Related Report
      2013 Annual Research Report
  • [Book] Bioactive Compounds from Okinawan Marine Cyanobacteria. Se-Kwon Kim (Ed.), Marine Pharmacognosy:Trends and Applications2012

    • Author(s)
      Toshiaki Teruya, Osamu Ohno, Kiyotake Suenaga
    • Publisher
      CRC Press
    • Related Report
      2013 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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