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Development of Three-dimensional Micro- Rapid Prototyping Technique using Highspeed Confocal Scanner and Flow Measurement of Micro- Multiphase Flow

Research Project

Project/Area Number 23760144
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Fluid engineering
Research InstitutionThe University of Tokyo

Principal Investigator

OISHI Masamichi  東京大学, 生産技術研究所, 技術専門職員 (70396901)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywordsマイクロ光造形 / 共焦点スキャナ / デジタルミラーデバイス / マイクロ混相流 / マイクロ流
Research Abstract

In this study, we develop a rapid prototyping technique of a complex three-dimensional shape in a microchannel that in mind for use in the model experiment for the behavior elucidation of the red blood cells. We have proposed a three-dimensional lithography using DMD (digital mirror device) in combination with high-speed confocal scanner. The optical design to eliminate the illumination non-uniformity is particularly concerned by introducing a beam homogenizer and spatial filter, and it reduces to 10% the difference in brightness over the entire region. Since the curing spot of confocal effect is tend to be thicker than the theoretical confocal depths, the possibility of thinner polymerization is indicated by decreasing the intensity of the laser and a longer exposure time.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (18 results)

All 2013 2012 2011 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (10 results) Remarks (2 results)

  • [Journal Article] Continuous and Simultaneous Measurement of the Tank-Treading Motion of Red Blood Cells and Surrounding Flow Using Translational Confocal Micro-Particle Image Velocimetry (Micro-PIV) with Sub-Micron Resolution2012

    • Author(s)
      M. Oishi, K. Utsubo, H. Kinoshita, T. Fujii, M. Oshima
    • Journal Title

      Measurement Science and Technology

      Volume: Vol.23

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Study on the mechanism of droplet formation in T-junction microchannel2012

    • Author(s)
      Xiao-Bin Li, Feng-Chen Li, Juan-Cheng Yang, Haruyuki Kinoshita, Masamichi Oishi and Marie Oshima
    • Journal Title

      Chemical Engineering Science

      Volume: 69 Issue: 1 Pages: 340-351

    • DOI

      10.1016/j.ces.2011.10.048

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Continuous and Simultaneous Measurement of the Tank-Treading Motion of Red Blood Cells and Surrounding Flow Using Translational Confocal Micro-Particle Image Velocimetry (Micro-PIV) with Sub-Micron Resolution2012

    • Author(s)
      Masamichi Oishi, Koji Utsubo, Haruyuki Kinoshita, Teruo Fujii, Marie Oshima
    • Journal Title

      Measurement Science and Technology

      Volume: 23 Issue: 3 Pages: 1-18

    • DOI

      10.1088/0957-0233/23/3/035301

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Study on the mechanism of droplet formation in T-junction microchannel2011

    • Author(s)
      X-B. Li, F-C. Li, J-C. Yang, H. Kinoshita, M. Oishi and M. Oshima
    • Journal Title

      Chemical Engineering Science

      Volume: Vol.22

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneous Measurement of Internal and Surrounding Flows of a Moving Droplet Using Multicolour Confocal Micro-Particle Image Velocimetry (micro-PIV)2011

    • Author(s)
      M. Oishi, H. Kinoshita, T. Fujii, M. Oshima
    • Journal Title

      Measurement Science and Technology

      Volume: Vol.22

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneous measurement of internal and surrounding flow of a moving droplet using multicolour confocal micro-particle image velocimetry2011

    • Author(s)
      M.Ohishi, H.Kinoshita, T.Fujii, M.Oshima
    • Journal Title

      Measurement Science and Technology

      Volume: Vol.22 Issue: 10 Pages: 1-13

    • DOI

      10.1088/0957-0233/22/10/105401

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] MEASUREMENT OF THREE DIMENSIONAL FLOW STRUCTURE DURING MICRODROPLET FORMATION USING PHASE-LOCKED MULTICOLOR CONFOCAL MICRO-PIV2013

    • Author(s)
      M. Oishi, H. Kinoshita, T. Fujii and M. Oshima
    • Organizer
      The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013)
    • Place of Presentation
      Freiburg, Germany
    • Year and Date
      2013-01-29
    • Related Report
      2013 Final Research Report
  • [Presentation] MEASUREMENT OF THREE DIMENSIONAL FLOW STRUCTURE DURING MICRODROPLET FORMATION USING PHASE-LOCKED MULTICOLOR CONFOCAL MICRO-PIV2013

    • Author(s)
      M. Oishi, H. Kinoshita, T. Fujii and M. Oshima
    • Organizer
      The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences
    • Place of Presentation
      Freiburg, Germany
    • Related Report
      2013 Annual Research Report
  • [Presentation] 混相流断層画像を基にした液滴の3次元形状の再構築2013

    • Author(s)
      松浦佑樹,大石正道,向井信彦,大島まり,張英夏
    • Organizer
      映像表現&コンピュータグラフィックス研究会
    • Place of Presentation
      久留米
    • Related Report
      2013 Annual Research Report
  • [Presentation] マイクロT字ジャンクションにおける液滴生成現象のマイクロPIV計測2013

    • Author(s)
      大石正道,木下晴之,藤井輝夫,大島まり
    • Organizer
      日本機械学会2013年度年次大会講演論文集
    • Place of Presentation
      岡山
    • Related Report
      2013 Annual Research Report
  • [Presentation] Phase-locked confocal micro-PIV measurement of three dimensional flow structure of transient droplet formation mechanism in T-shaped micro junction2012

    • Author(s)
      M. Oishi, H. Kinoshita, T. Fujii, M. Oshima
    • Organizer
      65th Annual Meeting of the APS Division of Fluid Dynamics (APS-DFD 2012)
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2012-11-20
    • Related Report
      2013 Final Research Report
  • [Presentation] Visualization and Measurement of Flow-Induced Dynamic Motion of Red Blood Cells Using Tracking Confocal Micro-PIV System2012

    • Author(s)
      M. Oshima, M. Oishi, H. Kinoshita, T. Fujii
    • Organizer
      ASME 2012 Summer Bioengineering Conference (SBC2012)
    • Place of Presentation
      Puerto Rico, USA
    • Year and Date
      2012-06-22
    • Related Report
      2013 Final Research Report
  • [Presentation] Phase-locked confocal micro-PIV measurement of three dimensional flow structure of transient droplet formation mechanism in T-shaped micro junction2012

    • Author(s)
      Masamichi Oishi, Haruyuki Kinoshita, Teruo Fujii, Marie Oshima
    • Organizer
      65th Annual Meeting of the APS Division of Fluid Dynamics
    • Place of Presentation
      San Diego, CA, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Simultaneous Measurement of Tank-Treading Motion of Red Blood Cell and Surrounding Flow using Target-Tracking Confocal Micro-PIV2011

    • Author(s)
      M. Oishi, K. Utsubo, H. Kinoshita, T. Fujii, M. Oshima
    • Organizer
      The 11th Asian Symposium on Visualization (ASV-11)
    • Place of Presentation
      Niigata, Japan
    • Year and Date
      2011-06-06
    • Related Report
      2013 Final Research Report
  • [Presentation] Simultaneous Measurement of Tank-Treading Motion of Red Blood Cell and Surrounding Flow using Target-Tracking Confocal Micro-PIV2011

    • Author(s)
      Masamichi Oishi, Koji Utsubo, Haruyuki Kinoshita, Teruo Fujii, Marie Oshima
    • Organizer
      The 11th Asian Symposium on Visualization
    • Place of Presentation
      Toki Messe, Niigata, Japan
    • Related Report
      2011 Research-status Report
  • [Presentation] Visualization and Measurement of Flow-Induced Dynamic Motion of Red Blood Cells Using Tracking Confocal Micro-PIV System

    • Author(s)
      Marie Oshima, Masamichi Oishi, Haruyuki Kinoshita, Teruo Fujii
    • Organizer
      ASME 2012 Summer Bioengineering Conference (SBC2012)
    • Place of Presentation
      Puerto Rico, USA
    • Related Report
      2012 Research-status Report
  • [Remarks]

    • URL

      http://www.oshimalab.iis.u-tokyo.ac.jp/english/

    • Related Report
      2013 Final Research Report
  • [Remarks] Hemodynamics, Microfluidics in Micro-TAS

    • URL

      http://www.oshimalab.iis.u-tokyo.ac.jp

    • Related Report
      2012 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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