| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
Plants have evolved specialized storage organelles to enable the stable accumulation of massive amounts of disulfide-rich reserve proteins in seeds. In this study, we aimed at unravelling the molecular mechanism for controlling the formation of protein disulfide bonds in plant cells. Using the rice endosperm as a model system, we identified thiol-disulfide oxidoreductases showing the high catalytic efficiency in disulfide bond formation and reduction and regulating the development of storage organelles.
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