Study on the formation of two polymorphs of cellulose I in Oikopleura
Project/Area Number |
23780191
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Wood science
|
Research Institution | 沖縄科学技術大学院大学 |
Principal Investigator |
NAKASHIMA Keisuke 沖縄科学技術大学院大学, マリンゲノミックスユニット, 研究員 (10422924)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
Keywords | セルロース / セルロース合成酵素 / 結晶多形 / アロモルフ / 単位胞 / オタマボヤ / ワカレオタマボヤ / 被嚢動物 |
Research Abstract |
To understand molecular mechanisms behind crystallization processes in cellulose biosynthesis, we analyzed the two cellulose synthases in the marine chordate Oikopleura dioica, those are proposed to be involved in the formation of two polymorphs of cellulose I. With negative results in assessing the embryos injected with mRNAs encoding mutated cellulose synthases, we challenged to express native forms using heterologous system with bacterial, yeast, and insect cell hosts.
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Report
(3 results)
Research Products
(10 results)