Isolation of the skin progenitor cells in canine allergic dermatitis and their application for the pathogenesis
| Project/Area Number |
23780330
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical veterinary science
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| Research Institution | Azabu University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 皮膚前駆細胞 / アレルギー性皮膚炎 / 犬 / 創傷治癒 / 骨髄造血幹細胞 / CD34 |
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| Research Abstract |
Role of the skin progenitor cells in the pathogenesis of allergic dermatitis (AD) was evaluated by using dogs, known to spontaneously develop the disease. We found CD34-positive skin progenitor cells were localized in the skin lesion of canine AD. An isolation method of CD34-positive hematopoietic progenitor cells was developed for the in vitro studies. Our results and established methods could be useful for the further research of the mechanisms of skin progenitor cells in the allergic inflammation.
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Report
(3 results)
Research Products
(26 results)
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[Journal Article] A case of cutaneous sterile pyogranuloma/ granuloma syndrome in a Maltese2013
Author(s)
Kawarai, S., Matsuura, S., Yamamoto, S., Kiuchi, A., Kanemaki, N., Madarame, H., Shirota, K
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Journal Title
J Am Anim Hosp Assoc
Volume: (in press)
Related Report
Peer Reviewed
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