Development of Novel Chip for Isolation of Circulating Tumor Cells Using Size-Selection and Photochemical Reaction
| Project/Area Number |
23790023
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
ARIYASU Shinya 東京理科大学, 総合研究機構, ポストドクトラル研究員 (50586998)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 光切断リンカー / 血中循環癌細胞 / 光分解反応 / シリコン基板 / 抗体 / キノリノール |
|---|
| Research Abstract |
The isolation of circulating tumor cells (CTCs) is expected toearly-diagnosis and tailor-made care of cancer. However, although the detection of CTCs was reported, the collection of living CTCs have been not realized. In this project, we developed microfluidic device composed of size-selection andIgG-coated photoreactive silicon device. This photoreactive IgG-coated silicon device can capture the target cells from cell-mixture and collect the living target cells by photoirradiation.
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Report
(3 results)
Research Products
(33 results)
