Identification of responsible gene(s) for congenital heart defect using the model mice of Down syndrome
| Project/Area Number |
23791194
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pediatrics
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| Research Institution | Keio University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ダウン症 / 心奇形 / ノックアウトマウス / Zfp295 / ヒト人工染色体 / 遺伝子量効果 |
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| Research Abstract |
In this study, we focused on the congenital heart defect that is observed with relatively high frequency in the patients with Down syndrome, and attempted to generate the knockout mice of Zfp295 that is one of the candidate genes for Down syndrome congeni
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Report
(3 results)
Research Products
(2 results)
