Study of mechanism of a rapid and profound transition in glucose concentration during the Pringle maneuver
Project/Area Number |
23791709
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Anesthesiology/Resuscitation studies
|
Research Institution | Kochi University |
Principal Investigator |
FUKUNAGA Kayo 高知大学, 教育研究部医療学系, 助教 (00571035)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 肝虚血再潅流 / 人工膵臓 / 血糖変動 / 周術期血糖管理 |
Research Abstract |
The Pringle maneuver is performed in hepatectomy due to reduce hemorrhage. Our previous study using a continuous blood glucose monitoring revealed that liver ischemia/reperfusion causes a rapid and profound transition in glucose concentration. Our study showed that glucose release from the hepatic vein and sinusoid leads to a rapid elevation in systemic blood glucose levels after liver ischemia/reperfusion. Furthermore, we investigated whether iatrogenic blood glucose variation cause inflammation.
|
Report
(3 results)
Research Products
(2 results)