Neuroprotective effect of lutein against light-induced damage

• Project/Area Number: 23792004
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Ophthalmology
• Research Institution: Keio University
• Principal Investigator: MABUCHI Haruna 慶應義塾大学, 医学部, 研究員 (70465011)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 網膜 / 光障害 / 酸化ストレス / 細胞死 / 視細胞

Research Abstract

Although retinitis pigmentosa is one of the leading causes of blindness worldwide, currently, no effective treatment is established. Light exposure is the traditionally known risk factor to exacerbate this disease through the photoreceptor death. But the