Involvement of signal pathway and apoptosis of cardioprotection by regular ethanol consumption
| Project/Area Number |
23792395
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
KANEDA Kazuhiro 大阪歯科大学, 歯学部, 講師(非常勤) (90533886)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 虚血心筋 / 心筋保護 / エタノール / シグナル伝達 / アポトーシス |
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| Research Abstract |
Bradykinin has been implicated in ischemic preconditioning and has been shown to induce mitochondrial reactive oxygen species generation through nitric oxide (NO). I investigated the involvement of the bradykinin B2 receptor (BKB2R) and measured NO production in chronic ethanol-induced cardioprotection.
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Report
(3 results)
Research Products
(29 results)
