Periodontal regeneration using calcified periodontal ligament cell sheet and artificial peptide
Project/Area Number |
23792465
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Periodontal dentistry
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Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
AKIZUKI Tatsuya 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 (50401378)
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Project Period (FY) |
2011 – 2013
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 歯周組織再生 / 骨補填材 / βリン酸三カルシウム / 歯周病 / 歯周組織 / 再生 / 細胞治療 / beta TCP |
Research Abstract |
The ultimate goal of periodontal treatment is to regenerate lost tissue caused by periodontitis. However, it is still difficult to regenerate lost tissue in case of the lost tissue has less periodontal ligament. The objective of this research was to evaluate the effectiveness of the calcified periodontal ligament on periodontal regeneration. Although we couldn't show the positive result, we explored the noble bone grafting material has unique structure for bone formation. We successfully showed that this material could regenerate periodontal tissue even in large defect model.
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Report
(4 results)
Research Products
(20 results)
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[Journal Article] Current and future periodontal tissue engineering2011
Author(s)
Izumi Y, Aoki A, Yamada Y, Kobayashi H, Iwata T, Akizuki T, Suda T, Nakamura S, Wara-Aswapati N, Ueda M, Ishikawa I
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Journal Title
Periodontology 2000
Volume: 56(1)
Pages: 166-87
Related Report
Peer Reviewed
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[Presentation] β-TCPゼラチンハイドロゲル,歯根膜細胞,rhFGF-2を併用した歯周組織再生-イヌ根分岐部歯周組織欠損-2013
Author(s)
星嵩, 秋月達也, 松浦孝典, 井川貴博, 竹内祥吾, 丸山起一, 小野彌, 小田茂, 松井誠,田畑泰彦, 和泉雄一
Organizer
第56回秋季日本歯周病学会学術大会
Place of Presentation
前橋
Year and Date
20130000
Related Report
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[Presentation] Periodontal tissue regeneration using random tunnel beta-TCP ceramics in dogs2012
Author(s)
Matuura T, Akizuki T, Hoshi S, Kinoshita A, Sunaga M, Ikawa T, Imamura R, Kimura M, Kuboki Y, Izumi Y
Organizer
98th Annual Meeting American Academy of Periodontology
Place of Presentation
Los Angeles, U.S.A.
Year and Date
20120000
Related Report
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[Presentation] β-TCPゼラチンハイドロゲル,歯根膜細胞,rhFGF-2を併用した歯周組織再生-イヌ根分岐部歯周組織欠損-.
Author(s)
星嵩, 秋月達也, 松浦孝典, 井川貴博, 竹内祥吾, 丸山起一, 小野彌, 小田茂, 松井誠, 田畑泰彦, 和泉雄一.
Organizer
第56回秋季日本歯周病学会学術大会
Place of Presentation
前橋
Related Report
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