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Analysis of the circadian brain network resposible for light entrainment in Drosophila melanogaster

Research Project

Project/Area Number 23870021
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Animal physiology/Animal behavior
Research InstitutionOkayama University

Principal Investigator

YOSHII Taishi  岡山大学, 大学院・自然科学研究科, 助教 (50611357)

Research Collaborator TOMIOKA Kenji  岡山大学, 大学院・自然科学研究科, 教授 (30136163)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords概日時計 / 体内時計 / キイロショウジョウバエ / 時計細胞 / 光受容 / ショウジョウバエ / 神経ネットワーク / 神経ペプチド
Research Abstract

The fruit fly Drosophila melanogasterhas multiple light-input pathways for light entrainment for the circadian clock. Especially, a blue light photo-pigment Cryptochrome (CRY) plays an important role in the pathway. Here, we investigated the brain neural network responsible for the CRY-dependent light entrainment. We found that a subset of pacemaker neurons promotes recovery from 8 h Jetlag in Drosophila, suggesting that there is a neural mechanism involved in the speed of light-entrainment.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • Research Products

    (21 results)

All 2013 2012 2011 Other

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Presentation (6 results) Book (2 results) Remarks (3 results)

  • [Journal Article] Long-term effect of systemic RNA interference on circadian clock genes in hemimetabolous insects2013

    • Author(s)
      Uryu O, Kamae Y, Tomioka K, Yoshii T
    • Journal Title

      Journal of Insect Physiology

      Volume: 59 Pages: 494-499

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Long-term effect of systemic RNA interference on circadian clock genes in hemimetabolous insects.2013

    • Author(s)
      Uryu O, Kamae Y, Tomioka K, Yoshii T
    • Journal Title

      Journal of Insect Physiology

      Volume: 59 Pages: 494-499

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase-shifting the fruit fly clock without Cryptochrome2012

    • Author(s)
      Kistenpfennig C, Hirsh J, Yo shi i T,Helfrich-Forster C
    • Journal Title

      Journal of Biological Rhythms

      Volume: 27 Pages: 117-125

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The dual oscillator system of Drosophila melanogasterunder natural-like temperature cycles2012

    • Author(s)
      Bywalez W, Menegazzi P, Rieger D, Schmid B, Helfrich-Forster C, Yoshii T
    • Journal Title

      Chronobiology International

      Volume: 29 Pages: 395-407

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Laboratory vs Nature: The Two Sides of the DrosophilaCircadian Clock2012

    • Author(s)
      Menegazzi P, Yoshii T, Helfrich-Forster C
    • Journal Title

      Journal of Biological Rhythms

      Volume: 27 Pages: 433-42

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Peripheral circadian rhythms and their regulation mechanism in insects and some other arthropods: a review. Journal of Comparative Physiology B: Biochemical2012

    • Author(s)
      Tomioka K, Uryu O, Kamae Y, Umezaki Y, Yo shi i T
    • Journal Title

      systemic, and environmental physiology

      Volume: 182 (6) Pages: 729-740

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Laboratory vs Nature: The Two Sides of the Drosophila Circadian Clock.2012

    • Author(s)
      Menegazzi P, Yoshii T, Helfrich-Foerster C
    • Journal Title

      Journal of Biological Rhythms

      Volume: 27 Pages: 433-42

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase-shifting the fruit fly clock without Cryptochrome.2012

    • Author(s)
      Kistenpfennig C, Hirsh J, Yoshii T, Helfrich-Foerster C
    • Journal Title

      Journal of Biological Rhythms

      Volume: 27 Pages: 117-125

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Peripheral circadian rhythms and their regulation mechanism in insects and some other arthropods: a review.2012

    • Author(s)
      Tomioka K, Uryu O, Kamae Y, Umezaki Y, Yoshii T
    • Journal Title

      Journal of Comparative Physiology B: Biochemical, systemic, and environmental physiology

      Volume: 182 Pages: 729-740

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The dual oscillator system of Drosophila melanogaster under natural-like temperature cycles.2012

    • Author(s)
      Bywalez W, Menegazzi P, Rieger D, Schmid B, Helfrich-Foerster C, Yoshii T
    • Journal Title

      Chronobiology International

      Volume: 29 Pages: 395-407

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Sexual interaction influences circadian activity pattern in Drosophila melanogaster2012

    • Author(s)
      Yoshii T, Hanafusa S, Umezaki Y, Tomioka K
    • Organizer
      SRBR 2012 Society for Research on Biological rhythms
    • Place of Presentation
      Destin, Florida, U.S.A
    • Related Report
      2012 Final Research Report
  • [Presentation] The neuronal network of the circadian clock and its synchronization to environmental cycles in Drosophila melanogaster2012

    • Author(s)
      Yo shi i T
    • Organizer
      第83回日本動物学会
    • Place of Presentation
      大阪府豊中市大阪大学豊中キャンパス
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] CRYが関与するキイロショウジョウバエ概日時計の磁気受容2012

    • Author(s)
      吉井大志
    • Organizer
      第19回日本時間生物学会学術大会
    • Place of Presentation
      北海道札幌市北海道大学
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Sexual interaction influences circadian activity pattern in Drosophila melanogaster.2012

    • Author(s)
      Taishi Yoshii, Shiho Hanafusa, Yujiro Umezaki, Kenji Tomioka
    • Organizer
      SRBR 2012
    • Place of Presentation
      Florida, U.S.A
    • Related Report
      2012 Annual Research Report
  • [Presentation] 新規の概日リズム解析プログラムActogramJ2011

    • Author(s)
      吉井大志, Schmid B, Helfrich-Forster C
    • Organizer
      第82回日本動物学会
    • Place of Presentation
      北海道旭川市大雪クリスタルホール
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] ショウジョウバエNPF陽性時計細胞は夕方の活動と自由継続周期に関与する2011

    • Author(s)
      吉井大志, Hermann C, Dircksen H, Helfrich-Forster C
    • Organizer
      第18回 日本時間生物学会学術大会
    • Place of Presentation
      愛知県名古屋市名古屋大学
    • Related Report
      2012 Final Research Report
  • [Book] Neurobiology of Circadian Timing. Two clocks in the brain-an update of the Morning and Evening oscillator model in Drosophila. In: Andries Kalsbeek, Martha Merrow, Till Roenneberg and Russell G. Foster, editors: Progress in Brain Research2012

    • Author(s)
      Yo shi i T, Rieger D, Helfrich-Forster C
    • Publisher
      Elsevier
    • Related Report
      2012 Final Research Report
  • [Book] Neurobiology of Circadian Timing2012

    • Author(s)
      Yoshii T, Rieger D, Helfrich-Foerster C
    • Total Pages
      513
    • Publisher
      Elsevier
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.biol.okayama-u.ac.jp/tomioka1/top.html

    • Related Report
      2012 Final Research Report
  • [Remarks]

    • URL

      http://actogramj.neurofly.de/

    • Related Report
      2012 Final Research Report
  • [Remarks] Laboratory of Chronobiology

    • URL

      http://www.biol.okayama-u.ac.jp/tomioka1/top.html

    • Related Report
      2012 Annual Research Report

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Published: 2011-09-05   Modified: 2019-07-29  

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