Development of a multimodal ULF-MRI system with a highly sensitive atomic magnetometer
Project/Area Number |
24240081
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Research Category |
Grant-in-Aid for Scientific Research (A)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Medical systems
|
Research Institution | Kyoto University |
Principal Investigator |
KOBAYASHI Tetsuo 京都大学, 工学(系)研究科(研究院), 教授 (40175336)
|
Co-Investigator(Renkei-kenkyūsha) |
OIDA Takenori 京都大学, 大学院工学研究科, 助教 (70447910)
ITO Yosuke 京都大学, 大学院工学研究科, 助教 (20589189)
|
Project Period (FY) |
2012-10-31 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥27,430,000 (Direct Cost: ¥21,100,000、Indirect Cost: ¥6,330,000)
Fiscal Year 2014: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
Fiscal Year 2012: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
|
Keywords | 超低磁場 / MRI / 原子磁気センサ / EEG / MEG / 眼球運動 / 光ポンピング / 脳磁図 / 脳波 / 磁気センサ |
Outline of Final Research Achievements |
In this study, we investigated on a multimodal ultra-low field MRI (ULF-MRI) system with optically pumped atomic magnetometers (OPAMs) as magnetic sensors to measure biomagnetic fields and MR signals. First, we carried out theoretical and experimental experiments on a K-Rb hybrid-type OPAM and demonstrate that the hybrid OPAM enabled to increase spatial homogeneity. In addition, we proposed a new method enabling simultaneous multi-location measurements by using the hybrid OPAM. Meanwhile, we proposed a new method for directly detecting magnetic resonance (MR) signals using a module-type OPAM in ULF-MRI. For the direct detection, we newly designed an actively shielded bias-field tuning coil to match the resonant frequencies between MR signals and OPAM. The results of numerical analyses indicate that actively shielded bias-field tuning coil can be designed to match the resonant frequencies of MR signals indicating its feasibility as an MR sensor toward a multimodal ULF-MRI.
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Report
(4 results)
Research Products
(76 results)