| Budget Amount *help |
¥43,940,000 (Direct Cost: ¥33,800,000、Indirect Cost: ¥10,140,000)
Fiscal Year 2015: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥24,570,000 (Direct Cost: ¥18,900,000、Indirect Cost: ¥5,670,000)
Fiscal Year 2012: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
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| Outline of Final Research Achievements |
The aims of this study are to prepare suitable nanoparticles for surface-assisted desorption ionization mass spectroscopy and to understand the ionization mechanism by laser irradiation. Lager nanoparticles showed better soft-ionization ability. Therefore, milder increasing of the nanoparticle temperature is important for soft ionization. Also, sodium ion doped TiO2 nanoparticles showed a very high SALDI ability. This result strongly suggest that desorption of molecules by laser irradiation is quite effective and increasing of ionization ability of nanoparticles is an important key to obtain higher sensing ability of SALDI-MS systems.
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