Mechanism regulating germline sex determination in Drosophila
| Project/Area Number |
24247011
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Morphology/Structure
|
|---|
| Research Institution | University of Tsukuba (2015)
Okazaki Research Facilities, National Institutes of Natural Sciences |
|---|
Principal Investigator |
KOBAYASHI Satoru 筑波大学, 生命領域学際研究センター, 教授 (90225508)
|
|---|
| Project Period (FY) |
2012-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥45,500,000 (Direct Cost: ¥35,000,000、Indirect Cost: ¥10,500,000)
Fiscal Year 2015: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2014: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
Fiscal Year 2013: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2012: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
|
|---|
| Keywords | 生殖細胞 / 性決定 / ショウジョウバエ / ヒドラ / 始原生殖細胞 |
|---|
| Outline of Final Research Achievements |
In this study, we have been trying to clarify the mechanism regulating sex determination of the germline. Here, we report the identification of the candidate genes downstream of Sxl, which can autonomously initiate female development in primordial germ cells. Furthermore, we have performed a genomewide identification of the genes differentially expressed between male and female germline in Drosophila and Hydra. These results provide the basis for clarifying the conserved mechanism of germline sex determination in animals.
|
Report
(5 results)
Research Products
(20 results)
-
-
-
-
-
-
-
[Journal Article] Analysis of a novel gene, Sdgc, reveals sex chromosome-dependent differences of medaka germ cells prior to gonad formation.2014
Author(s)
Nishimura, T., Herpin, A., Kimura, T., Hara, I., Kawasaki, T., Nakamura, S., Yamamoto, Y., Saito, T.L., Yoshimura, J., Morishita, S., Tsukahara, T., Kobayashi, S., Naruse, K., Shigenobu, S., Sakai, N., Schartl, M. and Tanaka, M.
-
Journal Title
Development
Volume: 141
Issue: 17
Pages: 3363-3369
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
[Journal Article] Pri peptides are mediators of ecdysone for the temporal control of development2014
Author(s)
H. Chanut-Delalande, Y. Hashimoto, A. Pelissier-Monier, R. Spokony, A. Dib, T. Kondo, J. Bohere, K. Niimi, Y. Latapie, S. Inagaki, L. Dubois, P. Valenti, C. Polesello, S. Kobayashi, B. Moussian, K. White, S. Plaza, Y. Kageyama, and F. Payre
-
Journal Title
Nature Cell Biol.
Volume: 16
Issue: 11
Pages: 1035-1044
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
