| Budget Amount *help |
¥45,500,000 (Direct Cost: ¥35,000,000、Indirect Cost: ¥10,500,000)
Fiscal Year 2015: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2014: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
Fiscal Year 2013: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2012: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
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| Outline of Final Research Achievements |
In this study, we have been trying to clarify the mechanism regulating sex determination of the germline. Here, we report the identification of the candidate genes downstream of Sxl, which can autonomously initiate female development in primordial germ cells. Furthermore, we have performed a genomewide identification of the genes differentially expressed between male and female germline in Drosophila and Hydra. These results provide the basis for clarifying the conserved mechanism of germline sex determination in animals.
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