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Genetic and molecular mechanism for information processing in the brain of the silkworm, Bombyx mori

Research Project

Project/Area Number 24248011
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied entomology
Research InstitutionThe University of Tokyo

Principal Investigator

SHIMADA Toru  東京大学, 農学生命科学研究科, 教授 (20202111)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥45,110,000 (Direct Cost: ¥34,700,000、Indirect Cost: ¥10,410,000)
Fiscal Year 2014: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2013: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
Fiscal Year 2012: ¥20,800,000 (Direct Cost: ¥16,000,000、Indirect Cost: ¥4,800,000)
Keywords鱗翅目 / 産卵行動 / 吐糸・営繭行動 / 光周反応 / 休眠 / 遺伝子ノックアウト / RNA-seq / 営繭行動 / 配偶行動 / 脳機能 / 腹部神経節 / 連鎖解析 / 摂食行動
Outline of Final Research Achievements

To understand the brain function in lepidopteran insects, the silkworm mutants for the brain responses to environment or situation are invaluable genetic resources. In this project, strain "u80", which shows abnormal oviposition behavior without copulation, the mutant "Fl", which makes malformed cocoons because of abnormal spinning behavior, and the variant "Lm(e)", which shows photoperiodism in larval stages for diapause properties in the next generation, were utilized for genetic analyses, i.e. trials for positional clonings. As the results, the responsible regions for u80, Fl, and Lm(e) were localized on limited regions on chromosomes 10, 7, and 1, respectively.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (9 results)

All 2015 2014 2013

All Journal Article (5 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) (of which Invited: 1 results)

  • [Journal Article] A novel sucrose hydrolase from the bombycoid silkworms Bombyx mori, Trilocha varians, and Samia cynthia ricini with a substrate specificity for sucrose2015

    • Author(s)
      Huabing Wang, Takashi Kiuchi, Susumu Katsuma, and Toru Shimada
    • Journal Title

      Insect Biochemistry and Molecular Biology

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 昆虫の食性の進化を遺伝子で説明できるか?(特集「ゲノムで進化の謎を解く」).2015

    • Author(s)
      嶋田 透
    • Journal Title

      細胞工学

      Volume: 34(2) Pages: 202-207

    • Related Report
      2014 Annual Research Report
  • [Journal Article] カイコの遺伝資源とゲノム情報を利用した新たな研究展開.[特集:昆虫のゲノム研究と新産業への応用]2014

    • Author(s)
      嶋田 透
    • Journal Title

      JATAFFジャーナル

      Volume: 2(7) Pages: 15-23

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Mutation of a novel ABC transporter gene is responsible for the failure to incorporate uric acid in the epidermis of ok mutants of the silkworm, Bombyx mori2013

    • Author(s)
      Lingyan Wang, Takashi Kiuchi, Tsuguru Fujii, Takaaki Daimon, Muwang Lia, Yutaka Banno, Shingo Kikuta, Takahiro Kikawada, Susumu Katsuma, Toru Shimada
    • Journal Title

      Insect Biochemistry and Molecular Biology

      Volume: 43 Issue: 7 Pages: 562-571

    • DOI

      10.1016/j.ibmb.2013.03.011

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced expression of the dysbindin-like gene in the Bombyx mori ov mutant exhibiting mottled translucency of the larval skin. Genome 56(2): 101-108.2013

    • Author(s)
      Lingyan Wang, Takashi Kiuchi, Tsuguru Fujii, Takaaki Daimon, Muwang Li, Yutaka Banno, Susumu Katsuma, and Toru Shimada
    • Journal Title

      Genome

      Volume: 56(2) Issue: 2 Pages: 101-108

    • DOI

      10.1139/gen-2012-0127

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Genetic linkage analysis of female sexual behavior mutant in the silkmoth, Bombyx mori2015

    • Author(s)
      Masashi Yuasa, Takashi Kiuchi, Susumu Katsuma, Toru Shimada
    • Organizer
      The 4th Asia-Pacific Congress of Sericulture and Insect Biotechnology
    • Place of Presentation
      韓国・釜山
    • Year and Date
      2015-04-22 – 2015-04-25
    • Related Report
      2014 Annual Research Report
  • [Presentation] トランスクリプトーム解析が解き明かす昆虫の食性進化の機構2014

    • Author(s)
      嶋田透
    • Organizer
      新学術領域研究「ゲノム支援」公開シンポジウム「次世代ゲノム科学の最前線」
    • Place of Presentation
      東京国際フォーラム(東京都千代田区丸の内3-5-1)
    • Year and Date
      2014-01-21
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 油蚕遺伝子「B8斑油」(obt)のポジショナ ルクローニング2013

    • Author(s)
      湯浅 正志, 木内 隆史, 伴野 豊, 勝間 進, 嶋田 透
    • Organizer
      日本蚕糸学会第83回大会
    • Place of Presentation
      農林水産技術会議事務局筑波事務所本館
    • Related Report
      2012 Annual Research Report
  • [Presentation] コンジェニック系統を用いた休眠制御遺伝子同定の試み2013

    • Author(s)
      木内 隆史, 勝間 進, 嶋田 透
    • Organizer
      日本蚕糸学会第83回大会
    • Place of Presentation
      農林水産技術会議事務局筑波事務所本館
    • Related Report
      2012 Annual Research Report

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Published: 2013-05-15   Modified: 2019-07-29  

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