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Studies on Homeo-dynamics with Embodied cultured and Artificial Neural Circuits

Research Project

Project/Area Number 24300080
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Perception information processing/Intelligent robotics
Research InstitutionThe University of Tokyo

Principal Investigator

IKEGAMI Takashi  東京大学, 総合文化研究科, 教授 (10211715)

Co-Investigator(Kenkyū-buntansha) TAKAHASHI Hirokazu  東京大学, 先端科学技術研究センター, 講師 (90361518)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2014: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2013: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2012: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Keywords自律ロボット / 培養神経回路 / 学習 / 可塑性 / スパイクニューロン / シミュレーション / 培養神経細胞 / 自律運動ロボット / ヘッブ学習 / ホメオスタシス / サイバネティクス / 同期 / 神経発火 / CMOS電極アレイ / 移送エントロピー / izhikevich神経細胞
Outline of Final Research Achievements

We designed a feedback loop system between a robot and a neural circuit, where a (either cultured or artificial) neural circuit controls the robot's behavior and the information from the environment will be feedback onto the neural circuit. By studying this iteration of stimulus and behavior of the feedback loop system, i) we characterized the development of cultured neural circuit by the transfer entropy, and we discovered that ii) a cultured neural circuit can create a structure by this feedback looping and iii) this pattern obeys a new principle of "learning by avoiding stimulus" at the network level.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (30 results)

All 2015 2014 2013 2012

All Journal Article (11 results) (of which Peer Reviewed: 11 results,  Open Access: 1 results,  Acknowledgement Compliant: 3 results) Presentation (19 results) (of which Invited: 1 results)

  • [Journal Article] Spike-Timing Dependent Plasticity Induces Learning by Stimulation Avoidance in Spiking Neural Networks2015

    • Author(s)
      Lana Sinapayen, Atsushi Masumori, Nathaniel Virgo, and Takashi Ikegami
    • Journal Title

      the proceedings of ECAL2015

      Volume: -

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Learning by Stimulation-Avoidance Principle on Embodied Cultured Neuronal Cells.2015

    • Author(s)
      Atsushi Masumori, Norihiro Maruyama, Julien Hubert, Takeshi Mita, Douglas Bakkum, Hirokazu Takahashi and Takashi Ikegami
    • Journal Title

      the proceedings of ECAL2015

      Volume: -

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A Robotic Approach to Understanding the Role and the Mechanism of Vicarious Trial-And-Error in a T-Maze Task2014

    • Author(s)
      Eiko Matsuda, Julien Hubart and Takashi Ikegami
    • Journal Title

      PLoS ONE

      Volume: 9 Issue: 7 Pages: 0102708-0102708

    • DOI

      10.1371/journal.pone.0102708

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Investigating Extended Embodiment Using a Computational Model and Human Experimentation2013

    • Author(s)
      Sato, Y., Iizuka, H., Ikegami, T.
    • Journal Title

      Constructivist Foundations

      Volume: 9(1) Pages: 73-84

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Self-moving Oil Droplet as a Homeostat2013

    • Author(s)
      Ikegami, T.
    • Journal Title

      Constructivist Foundations

      Volume: 9(1) Pages: 114-114

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of neuronal cells of dissociated primary culture on high-density CMOS electrode array2013

    • Author(s)
      Matsuda, E., Mita, T., Hubert, J., Bakkum, Frey, D,U., Hierlemann, A., Takahashi, H., Ikegami, T.
    • Journal Title

      Proceedings of 35th International Conference of the IEEE Engineering in Medicine and Biology Society

      Volume: - Pages: 1045-1048

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hebbian Learning in a Multimodal Environment", In Liò, P. et a(l. eds.)2013

    • Author(s)
      Hubert, J., Matsuda, E., Ikegami, T.
    • Journal Title

      Advances in Artificial Life, ECAL 2013: Proceedings of the Twelfth European Conference on the Synthesis and Simulation of Living Systems

      Volume: - Pages: 698-705

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple time scales observed in spontaneously evolved neurons on high-density cmos electrode array2013

    • Author(s)
      Matsuda, E., Mita, T., Hubert, J., Oka, M., Bakkum, D., Frey, D,U., Takahashi, H., Ikegami, T.
    • Journal Title

      Proceedings of the Twelfth European Conference on the Synthesis and Simulation of Living Systems

      Volume: - Pages: 1075-1082

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 神経工学の潮流2013

    • Author(s)
      高橋宏知, 神保泰彦
    • Journal Title

      電気学会論文誌C電子情報システム部門誌

      Volume: 133(3) Pages: 544-549

    • NAID

      10031155345

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dissociated neuronal culture expressing ionotropic odorant receptors as a hybrid odorant biosensor -proof-of-concept study-2012

    • Author(s)
      Norio Tanada, Takeshi Sakurai, Hidefumi Mitsuno, Douglas J. Bakkum, Ryohei Kanzaki, Hirokazu Takahashi
    • Journal Title

      Analyst

      Volume: 137(15) Pages: 3452-3458

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] "Capabilities of a High-Density CMOS Microelectrode Array to Identify, Record, and Stimulate Individual Neurons in Cultured Networks.2012

    • Author(s)
      Douglas J Bakkum, Urs Frey, Jan Mueller, Michele Fiscella, Branka Roscic, Hirokazu Takahashi, Andreas Hierlemann
    • Journal Title

      Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays

      Pages: 206-207

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Multiple Time Scales Observed in Spontaneously Evolved Neurons on High-density CMOS Electrode Array2015

    • Author(s)
      Eiko Matsuda
    • Organizer
      2nd NeuroCMOS Workshop
    • Place of Presentation
      兵庫県神戸市、RIKEN Kobe Institute
    • Year and Date
      2015-01-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Spatio-Temporal Analysis of Activity in an Embodied Cultured Neural Network2015

    • Author(s)
      Atsushi Masumori
    • Organizer
      2nd NeuroCMOS Workshop
    • Place of Presentation
      兵庫県神戸市、RIKEN Kobe Institute
    • Year and Date
      2015-01-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] IIT as a Measure for a Pseudo-Conscious State of a Cultured Neural Network2015

    • Author(s)
      Takashi Ikegami
    • Organizer
      2nd NeuroCMOS Workshop
    • Place of Presentation
      兵庫県神戸市、RIKEN Kobe Institute
    • Year and Date
      2015-01-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Towards Computation with Neuronal Culture2015

    • Author(s)
      Hirokazu Takahashi
    • Organizer
      2nd NeuroCMOS Workshop
    • Place of Presentation
      兵庫県神戸市、RIKEN Kobe Institute
    • Year and Date
      2015-01-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Designing a Robotic Platform Controlled by Cultured Neural Cells.2014

    • Author(s)
      Maruyama, N., Masumori, A., Hubert, J., Mita, T., Bakkum, D., Takahashi, H. and Ikegami, T
    • Organizer
      ALIFE14
    • Place of Presentation
      NewYork, USA
    • Year and Date
      2014-07-30 – 2014-08-02
    • Related Report
      2014 Annual Research Report
  • [Presentation] 身体化された培養神経回路網䛾活動䛾時空間解析2014

    • Author(s)
      升森敦士 丸山典宏 三田毅 Urs Frey Douglas Bakkum 高橋宏知 池上高志
    • Organizer
      日本人工知能学会
    • Place of Presentation
      愛媛県松山市、ひめぎんホール
    • Year and Date
      2014-05-12 – 2014-05-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] 高密度電極アレイを用いた培養神経細胞による実環境ロボットの 構築2014

    • Author(s)
      丸山典宏 升森敦士 池上高志
    • Organizer
      日本人工知能学会
    • Place of Presentation
      愛媛県松山市、ひめぎんホール
    • Year and Date
      2014-05-12 – 2014-05-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] VTE and consciousness2013

    • Author(s)
      池上高志
    • Organizer
      Workshop on Language and Cognition in Embodied Agents
    • Place of Presentation
      Institute of Cognitive Sciences and Technologies, Roma, Italy
    • Related Report
      2013 Annual Research Report
  • [Presentation] homunculus (workshop title)2013

    • Author(s)
      池上高志
    • Organizer
      ICT&ART CONNECT 2013
    • Place of Presentation
      Center for Digital Technology, Brussels, Belgium
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Massive Data Flows2013

    • Author(s)
      池上高志
    • Organizer
      MDFワークショップ
    • Place of Presentation
      Institute of Complex Systems, Paris, France
    • Related Report
      2013 Annual Research Report
  • [Presentation] Analysis of Neuronal Cells by Dissociated Primary Culture on High-Density CMOS Electrode Array2013

    • Author(s)
      池上高志
    • Organizer
      35th Annual International IEEE EMBS Conference
    • Place of Presentation
      大阪国際コンベンションセンター, 大阪市, 大阪府
    • Related Report
      2013 Annual Research Report
  • [Presentation] Frequency Conversion using Sub-Threshold Dynamics in Artificial Spiking Neurons2013

    • Author(s)
      Julien Hubert and Takashi Ikegami
    • Organizer
      7th International Workshop on Natural Computing, IWNC 20-22
    • Place of Presentation
      東京大学(東京)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Capability of an 11,011-electrode CMOS array to study action potential propagation plasticity2012

    • Author(s)
      Douglas J Bakkum, Urs Frey, Jan Mueller, Michele Fiscella, Branka Roscic, Hirokazu Takahashi, Andreas Hierlemann
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2012-10-13
    • Related Report
      2012 Annual Research Report
  • [Presentation] 高密度CMOSアレイ上培養神経細胞の細胞体位置の推定2012

    • Author(s)
      三田毅, 石原裕也, Douglas Bakkum, Urs Frey, Andreas Hierlemann, 神崎亮平, 高橋宏知
    • Organizer
      第27回生体生理工学シンポジウム講演
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2012-09-18
    • Related Report
      2012 Annual Research Report
  • [Presentation] 高密度CMOSアレイの観測電位と神経細胞の生理学的特性2012

    • Author(s)
      三田毅, D. Bakkum, 棚田法男, U. Frey, A. Hierlemann, 神崎亮平, 高橋宏知
    • Organizer
      平成24年電気学会電子・情報・システム部門人会
    • Place of Presentation
      弘前大学(弘前市)
    • Year and Date
      2012-09-05
    • Related Report
      2012 Annual Research Report
  • [Presentation] ロボット実験による vicarious trial-and-error (VTE)の役割の解析2012

    • Author(s)
      松田英子, Hubert, J., 池上高志
    • Organizer
      2012年度人工知能学会全国大会(第26回)
    • Place of Presentation
      山口教育会館(山口市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] A Robotic Approach to Understand the Mechanism and the Role of Vicarious Trial-and-Error in a T-Maze Task2012

    • Author(s)
      Eiko Matsuda, Hubert Julien, Takashi Ikegami
    • Organizer
      Summer School in Cognitive Sciences 2012,
    • Place of Presentation
      Montreal, Canada
    • Related Report
      2012 Annual Research Report
  • [Presentation] Information integration of multimodal systems2012

    • Author(s)
      松田英子
    • Organizer
      Ikegami Lab. Summer Workshop 2012 - Artificial Minds and Real Brains
    • Place of Presentation
      北海道大学(札幌)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 理系の学生に見られる共感覚者の割合とその内容2012

    • Author(s)
      松田英子, Tom Froese, 北村英哉, 開一夫
    • Organizer
      日本認知科学会第9回大会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2012 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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