Physical therapy to promote the recovery from muscle injury in rat
| Project/Area Number |
24300191
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Nagoya University |
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Principal Investigator |
KAWAAKAMI Keisuke 名古屋大学, 医学(系)研究科(研究院), 准教授 (60195047)
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| Co-Investigator(Kenkyū-buntansha) |
SOKABE Masahiro 名古屋大学, 医学系研究科, 教授 (10093428)
曽我 浩之 近大姫路大学, 看護学部, 教授 (20282121)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2014: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2012: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
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| Keywords | 骨格筋 / 筋損傷 / 機械刺激 / 超音波 / ラット / リハビリテーション |
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| Outline of Final Research Achievements |
To evaluate the effect of ultrasound and stretching on recovery from muscle injury, changes in muscle force production and myogenic gene expressions were investigated in an LC-induced muscle injury mode of rat. We established the LC-induced muscle injury model, whose injury was histologically confirmed to be equivalent. The results show that ultrasonic stimulation and stretching added once after muscle injury on the TA effectively promotes recovery from muscle injury according to histological and physiological evaluation. Additionally, during recovery from muscle injury the activation of muscle satellite cells early after muscle injury is suggested to be involved.
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Report
(4 results)
Research Products
(15 results)
