Production of the super catalytic antibody inhibiting the pandemic of influenza virus
| Project/Area Number |
24350085
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemistry related to living body
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| Research Institution | Oita University |
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Principal Investigator |
HIFUMI EMI 大分大学, 全学研究推進機構, 教授 (90254606)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2015: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Keywords | 抗体酵素 / インフルエンザウィルス / 抗体軽鎖 / 構造多様性 / 抗体 / インフルエンザウイルス / 核酸分解 / 軽鎖定常領域 / 感染抑制 |
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| Outline of Final Research Achievements |
We have carried out to develop several items such as production method, purification method, enzymatic function, anti influenza activity of super catalytic antibody in accordance with the schedule planned in the application form. We have made a huge development in the production method as well as the anti influenza function of human catalytic antibody. Regarding the structural diversity of catalytic antibody, we have discovered the novel method to solve the difficult and long-term issue on diversity.
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Report
(5 results)
Research Products
(26 results)
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[Presentation] 抗体酵素の構造多様性を解決する一方法2015
Author(s)
一二三 恵美, 松本 真吾, 中島 弘貴, 糸永 省吾, 宇田 泰三
Organizer
第２５回バイオ高分子シンポジウム
Place of Presentation
東工大・大岡山キャンパス（東京都・目黒区）
Year and Date
2015-07-23
Related Report
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[Presentation] スーパー抗体酵素の発見と展開2014
Author(s)
一二三恵美
Organizer
第24回バイオ・高分子シンポジウム
Place of Presentation
東京工業大学大岡山キャンパス（東京都・目黒区）
Year and Date
2014-07-23 – 2014-07-24
Related Report
Invited
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