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Elucidation of stress tensor inside cell and tissue by kinetic analysis using femtosecond laser impulse

Research Project

Project/Area Number 24360027
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Applied optics/Quantum optical engineering
Research InstitutionNara Institute of Science and Technology

Principal Investigator

Hosokawa Yoichiroh  奈良先端科学技術大学院大学, 物質創成科学研究科, 准教授 (20448088)

Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2015: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Keywordsフェムト秒レーザー / 原子間力顕微鏡 / 生体計測 / 衝撃波 / 力学作用 / フェムト秒レーザー
Outline of Final Research Achievements

When an intense femtosecond laser is focused on a water medium under microscope, an explosive phenomenon is induced at the laser focal point, and then shock and stress waves due to the explosion propagate and act to small object near the laser focal point as an impulsive force. We developed a new method to elucidate stress tensor inside cell and tissue by utilizing the impulsive force. In this method, vibrational deformation of small biological object, such as zebrafish, cultured cell layer, and their phantom, was induced by the impulsive force and detected by atomic force microscope (AFM) as time course of the bending movement of the AFM cantilever. It was possible to detect even the deformation of single cell. Furthermore, the experimental results were compared with numerical simulation using finite element method (FEM) and the origin of the vibrational deformation was analyzed. We succeeded in evaluation of shape and elasticity of the small sample based on the vibration behavior.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (64 results)

All 2016 2015 2014 2013 2012 Other

All Journal Article (9 results) (of which Peer Reviewed: 8 results,  Acknowledgement Compliant: 3 results) Presentation (55 results) (of which Int'l Joint Research: 6 results,  Invited: 3 results)

  • [Journal Article] Mechanical response of single nerve cells estimated by femtosecond laser-induced impulsive force2015

    • Author(s)
      Takanori Iino, Tadahide Furuno, Man Hagiyama, Akihiko Ito, Yoichiroh Hosokawa
    • Journal Title

      Proceeding of SPIE

      Volume: 9355 Pages: 93550B-93550B

    • DOI

      10.1117/12.2078664

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nanoscale bending movement of biological micro-object induced by femtosecond laser impulse and its detection by AFM2014

    • Author(s)
      Masanobu Takenaka, Takanori Iino, Akira Nagatani, Yoichiroh Hosokawa
    • Journal Title

      Appl. Phys. Express

      Volume: 7 Issue: 8 Pages: 087002-087002

    • DOI

      10.7567/apex.7.087002

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Contribution of Stress Wave and Cavitation Bubble in Evaluation of Cell-Cell Adhesion by Femtosecond Laser-Induced Impulse2014

    • Author(s)
      Takanori Iino, Po-Lin Lin, Wen-Zhe Wang, Jia-Huei Deng, Yun-Chang Lu, Fu-Jen Kao, and Yoichiroh Hosokawa
    • Journal Title

      App. Phys. A

      Volume: 117 Issue: 1 Pages: 389-393

    • DOI

      10.1007/s00339-014-8498-9

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] フェムト秒レーザ誘起衝撃力の細胞への作用の力学モデル2014

    • Author(s)
      細川陽一郎,上段寛久,飯野敬矩
    • Journal Title

      レーザー加工学会誌

      Volume: 21 Pages: 163-169

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] On Fundamental Cellular Processes for Emergence of Collective Epitheli al Movement2013

    • Author(s)
      T. Hirashima, Y. Hosokawa, T. Iino, M. Nagayama
    • Journal Title

      Biology Open

      Volume: 0 Issue: 7 Pages: 1-7

    • DOI

      10.1242/bio.20134523

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Photomechanical ablation of biological tissue induced by focused femtosecond laser and its application for acupuncture2013

    • Author(s)
      Yoichiroh Hosokawa, Mika Ohta, Akihiko Ito, and Yutaka Takaoka
    • Journal Title

      Appl. Phys. A

      Volume: Vol.110 No.3 Issue: 3 Pages: 613-616

    • DOI

      10.1007/s00339-012-7138-5

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the distance between adherent mesenchymal stem cell and the focus of irradiation of femtosecond laser on cell replication capacity2012

    • Author(s)
      Jun Sakai, Daniel Roldan, Kosei Ueno, Hiroaki Misawa, Yoichiroh Hosokawa, Takanori Iino, Shigeyuki Wakitani, and Mutsumi Takagi
    • Journal Title

      Cytotechnology

      Volume: Vol.64 No.3 Issue: 3 Pages: 323-329

    • DOI

      10.1007/s10616-012-9437-2

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Novel application for pseudopodia proteomics using excimer laser ablation and two-dimensional difference gel electrophoresis2012

    • Author(s)
      Akihiko Ito, Takahiro Mimae, Ying-Shan-Zhu Yamamoto, Man Hagiyama, Jun Nakanishi, Masaoki Ito, Yoichiroh Hosokawa, Morihito Okada, Yoshinori Murakami and Tadashi Kondo
    • Journal Title

      Lab Invest.

      Volume: Vol.92 No.9 Pages: 1374-1385

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] フェムト秒レーザー誘起衝撃力によるAFM探針のねじれ運動の解析2012

    • Author(s)
      竹中将信,飯野敬矩,細川陽一郎
    • Journal Title

      電気学会光・量子デバイス研究会 資料

      Volume: OQD-12 Pages: 22-26

    • NAID

      10031118922

    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力とAFMによるゼブラフィッシュ胚の硬さ評価2016

    • Author(s)
      南野 大樹、宮本 敏男、山田 壮平、別所 康全、松井 貴輝、飯野 敬矩、細川 陽一郎
    • Organizer
      第63回応用物理学会春季学術講演会
    • Place of Presentation
      東京工業大学大岡山キャンパス(東京都目黒区)
    • Year and Date
      2016-03-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力による植物細胞膜の機械特性評価2016

    • Author(s)
      吹田啓介、片桐大輔、米田新、出村拓、 飯野敬矩、細川陽一郎
    • Organizer
      光・量子デバイス研究会
    • Place of Presentation
      石垣市民会館(沖縄県石垣市)
    • Year and Date
      2016-03-11
    • Related Report
      2015 Annual Research Report
  • [Presentation] Analysis of nm Vibrationof Micro-Biological Tissue Induced by Femtosecond Laser Impulse2016

    • Author(s)
      D. Minamino, T. Miyamoto, R. Fukushima, S. Yamada, T. Matsui, Y. Bessho, T. Iino, Y. Hosokawa
    • Organizer
      The 3rd NCTU-NAIST Joint Workshop on Laser Bio/Nano Science
    • Place of Presentation
      Hsinchu, Taiwan
    • Year and Date
      2016-01-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] AFM Detection of nm Vibration of Micro-Biological Object Induced by Femtosecond Laser Impulse 1: Vibration of Monolayer Cultured Cell2016

    • Author(s)
      T. Miyamoto, D.i Minamino, R. Fukushima, T. Iino, H. Yabu, Y. Hosokawa
    • Organizer
      Annual Meeting of the Physical Society of the Republic of China 2016
    • Place of Presentation
      Kaohsiung, Taiwan
    • Year and Date
      2016-01-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] AFM Detection of nm Vibration of Micro-Biological Object Induced by Femtosecond Laser Impulse 2: Vibration Zebrafish Embryo2016

    • Author(s)
      D. Minamino, T. Miyamoto, R. Fukushima, S. Yamada, T. Matsui, Y. Bessho, T. Iino, Y. Hosokawa
    • Organizer
      Annual Meeting of the Physical Society of the Republic of China 2016
    • Place of Presentation
      Kaohsiung, Taiwan
    • Year and Date
      2016-01-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] レーザー誘起衝撃力による細胞組織の力学応答解析2015

    • Author(s)
      宮本敏男、福嶋亮介、南野大樹、飯野敬矩、細川陽一郎
    • Organizer
      COMSOL CONFERENCE TOKYO 2015
    • Place of Presentation
      秋葉原UDXカンファレンス(東京都千代田区)
    • Year and Date
      2015-12-03
    • Related Report
      2015 Annual Research Report
  • [Presentation] Quantification of calcium ion response of single animal cells revealed by femtosecond laser-induced impulsive force2015

    • Author(s)
      Y. Hosokawa
    • Organizer
      The 26th CDB Meeting ”Mechanistic Perspectives of Multicellular Organization”
    • Place of Presentation
      理化学研究所多細胞システム形成研究センター(兵庫県神戸市)
    • Year and Date
      2015-09-08
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] AFM Detection of Vibration of Cellular Tissue induced by Femtosecond Laser Impulse2015

    • Author(s)
      T. Miyamoto, T. Iino, D. Minamino, R. Fukushima, N. Saito, Y. Hosokawa
    • Organizer
      The 26th CDB Meeting ”Mechanistic Perspectives of Multicellular Organization”
    • Place of Presentation
      理化学研究所多細胞システム形成研究センター(兵庫県神戸市)
    • Year and Date
      2015-09-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Experimental and theoretical analysis of femtosecond laser impulse and its application for plant cell physiology2015

    • Author(s)
      Y. Hosokawa
    • Organizer
      国立交通大學応用化學系103年 尖端生物分子探測
    • Place of Presentation
      Hsinchu, Taiwan
    • Year and Date
      2015-06-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Femtosecond Laser Processing and Manipulation of Plant Cells for Investigation of Plant Physiology2015

    • Author(s)
      Y. Hosokawa, T. Iino, A. Shigemasa, K. Oikawa, J. Kobayashi, M. Nishimura, A. Nagatani
    • Organizer
      The 7th International Congress on Laser Advanced Materials Processing
    • Place of Presentation
      北九州国際会議場(福岡県北九州市)
    • Year and Date
      2015-05-26
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Mechanical response of single nerve cells estimated by femtosecond laser-induced impulsive force2015

    • Author(s)
      Takanori Iino, Tadahide Furuno, Man Hagiyama, Akihiko Ito, Yoichiroh Hosokawa
    • Organizer
      SPIE Photonics West 2015
    • Place of Presentation
      The Moscone Center, San Francisco, USA
    • Year and Date
      2015-02-07 – 2015-02-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Freezing process of plant extract solution by femtosecond laser impulse2015

    • Author(s)
      Tatsuya Kono, Takanori Iino, Yushi Miki, Daisuke Takahashi, Yukio Kawamura, Matsuo Uemura, Yoichiroh Hosokawa
    • Organizer
      PSROC 2015 Annual Meeting
    • Place of Presentation
      National Tsing Hua University, Hsinchu, Taiwan
    • Year and Date
      2015-01-28 – 2015-01-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] Development of a New Atomic Force Microscopic Method to Estimate Mechanical Properties of Biological Micro-object Combined with Femtosecond Laser-induced Impulse2015

    • Author(s)
      Ryosuke Fukushima, Toshio Miyamoto, Takanori Iino, Yoichiroh Hosokawa
    • Organizer
      PSROC 2015 Annual Meeting
    • Place of Presentation
      National Tsing Hua University, Hsinchu, Taiwan
    • Year and Date
      2015-01-28 – 2015-01-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] Adhesive strength between a streptavidin microsphere and a biotin substrate evaluated by femtosecond laser impulse2015

    • Author(s)
      Akihiro Maruyama, Takeshi Yamakawa, Hirohisa Uedan, Takanori Iino, Yoichiroh Hosokawa
    • Organizer
      PSROC 2015 Annual Meeting
    • Place of Presentation
      National Tsing Hua University, Hsinchu, Taiwan
    • Year and Date
      2015-01-28 – 2015-01-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] Vibration Analysis of Pseudo-Cellular Tissue by Femtosecond Laser Impulse and Atomic Force Microscope2015

    • Author(s)
      Toshio Miyammoto, Ryosuke Fukushima, Takanori Iino, Hiroshi Yabu, Yoichiroh Hosokawa
    • Organizer
      PSROC 2015 Annual Meeting
    • Place of Presentation
      National Tsing Hua University, Hsinchu, Taiwan
    • Year and Date
      2015-01-28 – 2015-01-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] Motion Analysis of Biological Cell Induced by Femtosecond Laser Impulse2014

    • Author(s)
      H. Uedan, A. Maruyama, T. Iino, Y. Hosokawa
    • Organizer
      The 9th International Conference on Photo-Excited Processes and Applications (ICPEPA-9)
    • Place of Presentation
      くにびきメッセ(島根県松江市)
    • Year and Date
      2014-09-29 – 2014-10-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力による微小球状生体試料の振動応答解析2014

    • Author(s)
      福嶋亮介, 山田壮平, 宮本敏男, 飯野敬矩, 別所康全, 松井貴輝, 細川陽一郎
    • Organizer
      2014年 第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2014-09-17 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 生体分子添加水溶液にみられる集光フェムト秒レーザー誘起氷結晶成長2―結晶形状と成長速度の添加分子依存性―2014

    • Author(s)
      河野達也,澤田晃佑,飯野敬矩,三木雄史,高橋大輔,河村幸男,上村松生,細川陽一郎
    • Organizer
      2014年 第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2014-09-17 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力によるビオチン修飾基板 - アビジン修飾微小球間の接着力評価2014

    • Author(s)
      丸山彰大,山川 健,上段寛久,飯野敬矩,細川陽一郎
    • Organizer
      2014年 第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2014-09-17 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Analysis of Vibration of Micro-spherical Bio-object Induced by Femtosecond Laser Impulse2014

    • Author(s)
      Ryosuke Fukushima, Toshio Miyamoto, Takanori Iino, Yoichiroh Hosokawa
    • Organizer
      The 3rd International Summer Course and Workshop on Single Molecule/Nanoparticle Spectroscopy and Imaging
    • Place of Presentation
      National Chiao Tung University, Hsinchu, Taiwan
    • Year and Date
      2014-07-07 – 2014-07-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] How organ size is determined in zebrafish Kupffer’s vesicle?2014

    • Author(s)
      Hiroshi Ishikawa, Sohei Yamada, Naoyuki Tahara, Tatsuro Matta, Eri Sumino, Yasumasa Bessho1Yoichiro Hosokawa, and Takaaki Matsui
    • Organizer
      47th Annual Meeting for the Japanese Society of Developmental Biologists
    • Place of Presentation
      愛知県産業労働センター(愛知名古屋市)
    • Year and Date
      2014-05-27 – 2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 生体分子添加水溶液にみられる集光フェムト秒レーザー誘起氷結晶成長2014

    • Author(s)
      河野達也, 澤田晃佑, 飯野敬矩, 上村松生, 細川陽一郎
    • Organizer
      2014年第61回応用物理学会春季学術講演会
    • Place of Presentation
      青山学院大学(神奈川)
    • Related Report
      2013 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力と原子間力顕微鏡を用いた微小な植物試料の堅さ評価2014

    • Author(s)
      細川 陽一郎
    • Organizer
      第55回日本植物生理学会年会
    • Place of Presentation
      富山大学(富山)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Motion Analysis of Biological Cells and Micro-beads by Femtosecond Laser Impulse2014

    • Author(s)
      Hirohisa Uedan, Takanori Iino, F.C.Chang, R.H.Hung, C.H.Yu, F.J. Kao, Yoichiroh Hosokawa
    • Organizer
      The Physical Society of Republic of China (Taiwan) Annual Meeting 2014
    • Place of Presentation
      Taichung, Taiwan
    • Related Report
      2013 Annual Research Report
  • [Presentation] AFM detection of vibration of biological micro-object induced by femtosecond laser impulse2014

    • Author(s)
      Ryosuke Fukushima, Takanori Iino, Yoichiroh Hosokawa
    • Organizer
      The Physical Society of Republic of China (Taiwan) Annual Meeting 2014
    • Place of Presentation
      Taichung, Taiwan
    • Related Report
      2013 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力による細胞接着剥離の力学メカニズム(1)-数値解析による現象予測-2013

    • Author(s)
      細川陽一郎, 上段寛久, 飯野敬矩
    • Organizer
      2013年 第60回応用物理学会春季学術講演会
    • Place of Presentation
      神奈川工科大学(神奈川)
    • Year and Date
      2013-03-30
    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力による細胞間接着剥離の力学メカニズム(2)-モデル実験系による評価-2013

    • Author(s)
      上段寛久, 飯野敬矩, 細川陽一郎
    • Organizer
      2013年 第60回応用物理学会春季学術講演会
    • Place of Presentation
      神奈川工科大学(神奈川)
    • Year and Date
      2013-03-30
    • Related Report
      2012 Annual Research Report
  • [Presentation] 超短パルスレーザーによる微粒化処理を行ったZnS蛍光体の作製2013

    • Author(s)
      鍋坂恭平, 石河泰明, 土江貴洋, 田口信義, 細川陽一郎, 浦岡行治
    • Organizer
      2013年 第60回応用物理学会春季学術講演会
    • Place of Presentation
      神奈川工科大学(神奈川)
    • Year and Date
      2013-03-29
    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザー衝撃力により誘導される微小生物組織の力学応答のAFMによる検出2013

    • Author(s)
      竹中将信, 飯野敬矩, 細川陽一郎
    • Organizer
      レーザー学会学術講演会第33回年次大会
    • Place of Presentation
      姫路商工会議所(兵庫)
    • Year and Date
      2013-01-29
    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起 衝撃力による筋芽細胞の力学応答の個別解析2013

    • Author(s)
      細川 陽一郎, 坂口 さや香, 飯野 敬矩
    • Organizer
      2013年光化学討論会
    • Place of Presentation
      愛媛大学(愛媛)
    • Related Report
      2013 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力による細胞間接着剥離の力学メカニズム(3) ―擬似細胞の接着力の制御と運動の解析―2013

    • Author(s)
      上段寛久,飯野敬矩,細川陽一郎
    • Organizer
      2013年 第74回応用物理学会秋季学術講演会
    • Place of Presentation
      同志社大学(京都)
    • Related Report
      2013 Annual Research Report
  • [Presentation] バイオ分野におけるレーザープロセシング2013

    • Author(s)
      細川陽一郎
    • Organizer
      2013年 第74回応用物理学会秋季学術講演会
    • Place of Presentation
      同志社大学(京都)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 超短パルスレーザーを照射した無機ELディスプレイ用ZnS蛍光体の作製2013

    • Author(s)
      鍋坂恭平,石河泰明,土江貴洋,田口信義,細川陽一郎,浦岡行治
    • Organizer
      2013年 第74回応用物理学会秋季学術講演会
    • Place of Presentation
      同志社大学(京都)
    • Related Report
      2013 Annual Research Report
  • [Presentation] レーザー誘起衝撃力による細胞のインパルス力場応答解析2013

    • Author(s)
      細川陽一郎
    • Organizer
      応用物理学会 量子エレクトロニクス研究会 「バイオ・メディカルフォトニクス:基礎と応用の最前線」
    • Place of Presentation
      上智大学軽井沢セミナーハウス(長野)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Femtosecond Laser Irradiation to ZnS Phosphor for Inorganic Electroluminescent Displays2013

    • Author(s)
      Kyohei Nabesaka, Yasuaki Ishikawa, Takahiro Doe, Nobuyoshi Taguchi, Yoichiroh Hosokawa, and Yukiharu Uraoka
    • Organizer
      The 2013 International Meeting for Future of Electron Devices, Kansai
    • Place of Presentation
      Osaka, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Laser-Assisted Control of Protein Adsorption for Dynamically Arranging Viable Cells2013

    • Author(s)
      Kazunori Okano, Ai. Matsui, Yasuyo Maezawa, Mie Matsubara, Yoichiroh Hosokawa, Hiroshi Tsubokawa, FuJen Kao, Yaw-Kuen Li, and Hiroshi Masuhara
    • Organizer
      The 10th Conference on Lasers and Electro-Optics Pacific Rim(CLEO-PR 2013)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Nanoscale Bending Movement of Biological Micro-Object Induced by Femtosecond Laser Impulse and Its Detection by AFM2013

    • Author(s)
      Yoichiroh Hosokawa, Masanobu Takenaka, Takanori Iino
    • Organizer
      The 12th International Conference on Laser Ablation (COLA 2013)
    • Place of Presentation
      Ischia, Italy
    • Related Report
      2013 Annual Research Report
  • [Presentation] Motion Analysis of Micro-Beads activated by Femtosecond Laser Impulse2013

    • Author(s)
      Hirohisa Uedan, Takanori Iino, Yoichiroh Hosokawa
    • Organizer
      2013 GIST-NAIST-NCTU International Joint Symposium
    • Place of Presentation
      Nara, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] System Dsigning to Estimate Internal Stress of Micro-Biological Material Utilizing Femtosecond Laser Impulse and AFM2012

    • Author(s)
      Masanobu Takenaka, Takanori Iino, and Yoichiroh Hosokawa
    • Organizer
      GIST-NAIST-NCTU Joint Symposium
    • Place of Presentation
      Hsinchu, Taiwan
    • Year and Date
      2012-11-20
    • Related Report
      2012 Annual Research Report
  • [Presentation] Photo-Dynamc Conversion Of Solid Surface From Protein-Phobic to - Philic By Femtosecond Laser For In Situ Microfabrication2012

    • Author(s)
      Kazunori Okano, Yoichiroh Hosokawa, Hiroshi Tsubokawa, Hiroshi Masuhara, and Fu-Jen Kao
    • Organizer
      The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2012)
    • Place of Presentation
      Okinawa, Japan
    • Year and Date
      2012-10-31
    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力によるAFM探針のねじれ運動の解析2012

    • Author(s)
      竹中将信, 飯野敬矩, 細川陽一郎
    • Organizer
      電気学会光・量子デバイス研究会「バイオメディカルフォトニクス応用」
    • Place of Presentation
      東北大学東京分室(東京)
    • Year and Date
      2012-09-24
    • Related Report
      2012 Annual Research Report
  • [Presentation] Larger Intercellular Adhesion Strength Generates More Coherent and Directional Multicellular Movement-Measurement and Simulation2012

    • Author(s)
      Tsuyoshi Hiroshima, Takanori Iino, Yoichiroh Hosokawa, Masaharu Nagayama,
    • Organizer
      第50回日本生物物理学会年会
    • Place of Presentation
      名古屋大学(名古屋)
    • Year and Date
      2012-09-22
    • Related Report
      2012 Annual Research Report
  • [Presentation] 原子間力顕微鏡を用いたフェムト秒レーザー誘起衝撃力の時間変化の解析2012

    • Author(s)
      細川陽一郎, 飯野敬矩
    • Organizer
      第73回応用物理学会学術講演会
    • Place of Presentation
      愛媛大学・松山大学(愛媛)
    • Year and Date
      2012-09-12
    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力によるAFM探針のねじれ運動の誘導と応用2012

    • Author(s)
      竹中将信, 飯野敬矩, 細川陽一郎
    • Organizer
      第73回応用物理学会学術講演会
    • Place of Presentation
      愛媛大学・松山大学(愛媛)
    • Year and Date
      2012-09-12
    • Related Report
      2012 Annual Research Report
  • [Presentation] エネルギーと力と力積 : 物理パラメーターからみる細胞の接着2012

    • Author(s)
      細川陽一郎
    • Organizer
      第52回生物物理若手の会夏の学校
    • Place of Presentation
      支笏湖ユースホステル(北海道)(Invited)
    • Year and Date
      2012-09-02
    • Related Report
      2012 Annual Research Report
  • [Presentation] Evaluation of controllability of femtosecond laser-induced impulse in water utilizing atomic force microscopy2012

    • Author(s)
      Takanori Iino and Yoichiroh Hosokawa
    • Organizer
      8th International Conference on Photo-Excited Processes and Applications (ICPEPA-8)
    • Place of Presentation
      Rochester, USA,
    • Year and Date
      2012-08-13
    • Related Report
      2012 Annual Research Report
  • [Presentation] Time Resolved Analysis of Femtosecond Laser Impulse Induced in Water and Cell Culture Medium2012

    • Author(s)
      Yoichiroh Hosokawa and Takanori Iino
    • Organizer
      8th International Conference on Photo-Excited Processes and Applications (ICPEPA-8)
    • Place of Presentation
      Rochester, USA,(Invited)
    • Year and Date
      2012-08-12
    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力による細胞間接着と細胞内応力の評価の試み2012

    • Author(s)
      竹中将信, 飯野敬矩, 細川陽一郎
    • Organizer
      数理生物学サマーレクチャー「数理モデリングの基礎と応用」
    • Place of Presentation
      理化学研究所発生・再生科学総合研究センター(兵庫)
    • Year and Date
      2012-07-09
    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザ誘起衝撃力が拓くバイオテクノロジー2012

    • Author(s)
      細川陽一郎
    • Organizer
      第77回レーザ加工学会講演会
    • Place of Presentation
      大阪大学(大阪)(Invited)
    • Year and Date
      2012-05-24
    • Related Report
      2012 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力が基板に接着した微小物体にもたらす力学的作用

    • Author(s)
      丸山彰大、上段寛久、飯野敬矩、細川陽一郎
    • Organizer
      応用物理学会関西支部講演会
    • Place of Presentation
      奈良先端科学技術大学院大学(奈良)
    • Related Report
      2013 Annual Research Report
  • [Presentation] フェムト秒レーザーアブレーションと原子間力顕微鏡による生体微小試料の弾性変形の解析

    • Author(s)
      福嶋亮介、飯野敬矩、細川陽一郎
    • Organizer
      応用物理学会関西支部講演会
    • Place of Presentation
      奈良先端科学技術大学院大学(奈良)
    • Related Report
      2013 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力と原子間力顕微鏡による微小生体試料の力学的性質の解析

    • Author(s)
      福嶋亮介, 細川陽一郎, 飯野敬矩
    • Organizer
      電気学会 光・量子デバイス研究会
    • Place of Presentation
      東北大学東京分室(東京)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 細胞接着メカニズム解明のためのフェムト秒レーザー衝撃力によって引き剥がした微小物体の運動解析

    • Author(s)
      丸山彰大, 上段寛久, 坂口さや香, 飯野敬矩, 細川陽一郎
    • Organizer
      (社)レーザー学会第459回研究会「レーザーマイクロ・ナノプロセシング」
    • Place of Presentation
      宮崎市民プラザ(宮崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Motion Analysis of Biological Cells by Femtosecond Laser Impulse and Its Formulation

    • Author(s)
      Hirohisa Uedan, T. Iino, F.C.Chang, R.H.Hung, C.H.Yu, F.J. Kao, Y. Hosokawa
    • Organizer
      NCTU-NAIST-ITRC Joint Workshop on Laser Bio/Nano Science
    • Place of Presentation
      Hsinchu, Taiwan
    • Related Report
      2013 Annual Research Report
  • [Presentation] AFM detection of nano-meter vibration of plant root intduced by femtosecond laser impulse

    • Author(s)
      Ryosuke Fukushima, Takanori Iino and Yoichiroh Hosokawa
    • Organizer
      NCTU-NAIST-ITRC Joint Workshop on Laser Bio/Nano Science
    • Place of Presentation
      Hsinchu, Taiwan
    • Related Report
      2013 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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